Therapeutics News and Research

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Unlocking neuroglia’s potential to halt neurodegeneration and restore brain homeostasis

In a revealing Genomic Press Interview published today in Brain Medicine, Professor Alexei Verkhratsky dismantles decades of neuroscience orthodoxy with discoveries that position neuroglia as active architects of brain function rather than passive cellular bystanders.

26 Aug 2025

Investigating toxicity of common bisphenol replacements in food packaging

Chemicals used to replace bisphenol A (BPA) in food packaging can trigger potentially harmful effects in human ovarian cells, according to McGill University researchers.

26 Aug 2025

New research reveals why blood clotting malfunctions in inflammatory bowel disease

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD can also be deadly: up to 8% of people with the disease develop blood clots, which can lead to heart attack and stroke.

25 Aug 2025

Mount Sinai researchers develop MARQO to revolutionize cancer tissue analysis

Scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new computational tool that could transform how cancer tissues are analyzed and help pave the way for more personalized treatments.

25 Aug 2025

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

Researchers found that acoustic emission dose-an acoustic signal from microbubbles-could predict how to adjust ultrasound power and open the blood brain barrier for delivering drugs in patients with glioblastoma.

25 Aug 2025

New study reveals long road to seizure control for people with focal epilepsy

Antiseizure medications help the majority of people with focal epilepsy, a common form of the neurological disorder.

25 Aug 2025

Scientists discover molecular brake that halts brain cell repair in multiple sclerosis

A team of scientists led by the Institute for Glial Sciences (IGS) at Case Western Reserve University's School of Medicine has discovered a built-in "brake" that controls when key brain cells mature.

25 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer's disease clinical trials, a new USC study finds.

22 Aug 2025

Combination treatment approach shows promise for hard-to-treat triple-negative breast cancer

A new study led by researchers at the Icahn School of Medicine at Mount Sinai has found that adding the targeted therapy everolimus to standard carboplatin chemotherapy extends the time before disease progression in patients with advanced triple-negative breast cancer (TNBC), one of the most aggressive and hard-to-treat forms of breast cancer.

21 Aug 2025

Nanodroplet array revolutionizes search for new drugs

Until now, the early phase of drug discovery for the development of new therapeutics has been both cost- and time-intensive.

21 Aug 2025

Australian researchers identify GATOR1 complex as key to preventing lymphoma

Australian researchers have used an innovative genome-wide screening approach to identify genes, and their encoded proteins, that play critical roles in the prevention of lymphoma development, revealing new potential treatment targets for these blood cancers.

21 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Elevated TMAO levels linked to higher risk of abdominal aortic aneurysms

Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide) - a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products - and a higher risk of abdominal aortic aneurysms.

20 Aug 2025

Therapeutics News and Research

Unlocking neuroglia’s potential to halt neurodegeneration and restore brain homeostasis

Investigating toxicity of common bisphenol replacements in food packaging

New research reveals why blood clotting malfunctions in inflammatory bowel disease

Mount Sinai researchers develop MARQO to revolutionize cancer tissue analysis

Study identifies key metric for safe blood brain barrier opening in glioblastoma patients

New study reveals long road to seizure control for people with focal epilepsy

Scientists discover molecular brake that halts brain cell repair in multiple sclerosis

Next-gen sequencing reveals the regulatory potential of the non-coding genome

SOX2 drives progression and therapy resistance in advanced prostate cancer

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Combination treatment approach shows promise for hard-to-treat triple-negative breast cancer

Nanodroplet array revolutionizes search for new drugs

Australian researchers identify GATOR1 complex as key to preventing lymphoma

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

Elevated TMAO levels linked to higher risk of abdominal aortic aneurysms

Breakthrough in protein drug delivery could replace lengthy IV infusions

PathoPlex technology maps protein patterns across human organs

Young adults with bipolar disorder show signs of early heart dysfunction

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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