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Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research Institute, a center jointly promoted by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya.

28 Jun 2022

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

Researchers assessed the in vivo effectiveness of monoclonal antibodies and directly acting antiviral agents against the SARS-CoV-2 Omicron BA.1 and BA.2 sublineages.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Innovative treatment reduces post-traumatic headache related disability, study finds

The first therapy to be developed specifically for post-traumatic headache significantly reduced related disability in veterans following a traumatic brain injury (TBI).

27 Jun 2022

Treatment resistance for deadly form of kidney cancer linked to low mitochondrial content in the cell

Researchers at Karolinska Institutet in Sweden have linked resistance to treatment for a deadly form of kidney cancer to low mitochondrial content in the cell.

27 Jun 2022

Scientists create new fluorophores that could help fight cancer

Scientists from the Ural Federal University and the Ural Branch of the Russian Academy of Sciences have created new fluorescent chemical compounds (fluorophores) for photodynamic therapy of cancerous tumors, the latest method of treating cancer.

27 Jun 2022

Vitamin D supplements show promise to counter the adverse effects of diabetes drug on bone health

Vitamin D supplementation may help offset damaging bone loss that occurs in some people who take canagliflozin, a commonly prescribed diabetes drug.

27 Jun 2022

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.

27 Jun 2022

Does fecal viral excretion provide insights into on GI symptoms of COVID-19?

Researchers discuss the physiopathological mechanisms associated with digestive symptoms associated with COVID-19.

27 Jun 2022

C-reactive protein levels predict ED risk

A recent meta-analysis aimed to describe the relationship between C-reactive protein levels and erectile dysfunction.

27 Jun 2022

Bisphosphonates appear to improve COVID-19 exposure outcomes

A new retrospective study examines the effect of bisphosphonates on COVID-19 outcomes.

27 Jun 2022

LUCID: music, medicine, and machine learning

In this interview, News-Medical speaks to Zoë Thomson, Co-founder and Chief Innovation Officer of LUCID, about how music and machine learning are changing how we approach mental and neuropsychiatric health.

27 Jun 2022

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

AbbVie today announced the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended the approval of upadacitinib (RINVOQ® 15 mg, once daily) for the treatment of active non-radiographic axial spondyloarthritis (nr‑axSpA) in adult patients with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI), who have responded inadequately to nonsteroidal anti-inflammatory drugs (NSAIDs).*

27 Jun 2022

Health care startups turn to ‘coaches’ to help patients cope and monitor treatment

In 2011, Sean Duffy and Adrian James were sitting in San Francisco's Dolores Park debating what to call some workers at the company they founded, Omada Health.

24 Jun 2022

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

24 Jun 2022

COVID-19 rebound risks similar for Paxlovid and Molnupiravir

In a recent article posted to the medRxiv* preprint server, investigators in the United States illustrated that rebound of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can occur in some patients following molnupiravir and Paxlovid SARS-CoV-2 therapy.

23 Jun 2022

Therapy News and Research

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Effectiveness of monoclonal antibodies and directly acting antivirals against SARS-CoV-2 Omicron BA.1 and BA.2 sublineages

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Innovative treatment reduces post-traumatic headache related disability, study finds

Treatment resistance for deadly form of kidney cancer linked to low mitochondrial content in the cell

Scientists create new fluorophores that could help fight cancer

Vitamin D supplements show promise to counter the adverse effects of diabetes drug on bone health

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Does fecal viral excretion provide insights into on GI symptoms of COVID-19?

C-reactive protein levels predict ED risk

Bisphosphonates appear to improve COVID-19 exposure outcomes

LUCID: music, medicine, and machine learning

CHMP recommends approval of upadacitinib (RINVOQ®) for the treatment of adults with active non-radiographic axial spondyloarthritis

Health care startups turn to ‘coaches’ to help patients cope and monitor treatment

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

COVID-19 rebound risks similar for Paxlovid and Molnupiravir

Fragment crystallizable-altered COVID-19 antibodies efficacious across two animal models

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

'Brain bleeds' in infants can affect visual outcomes at the end of their primary school years

Molecular tumor profiling in pediatric cancer patients significantly impacts clinical care

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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