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Study uncovers key mechanism behind HIV latency

An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health report.

18 Nov 2024

Daily tablet shows promise in treating achondroplasia in children

A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study.

18 Nov 2024

Hypertension drug may reduce heart failure risk in people recovering from heart attack

New research found that the medication spironolactone, often prescribed for hypertension (high blood pressure), may reduce the risk of heart failure in people recovering from a heart attack.

18 Nov 2024

Rare variant analysis reveals genetic spectrum of monogenic diabetes genes

This study links rare genetic variants to type 2 diabetes risk, emphasizing their role in monogenic diabetes and potential for precision medicine integration.

18 Nov 2024

Electronic nudges boost flu vaccination rates among heart attack survivors

An electronic letter, or nudge, highlighting the cardiovascular benefits of influenza vaccines improved vaccination rates among more than 2 million adults—with a greater impact on those who have had a heart attack—across three clinical trials spanning the most-recent, two consecutive influenza seasons in Denmark.

18 Nov 2024

AI program enhances echocardiogram interpretation and reduces wait times

Using an artificial intelligence program to read echocardiograms may reduce the wait time for results and help lead to more timely medical care, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Intensive blood pressure treatment reduces cardiovascular risk in people with Type 2 diabetes

An intensive treatment approach to lowering high systolic blood pressure in people with Type 2 diabetes led to a reduced risk of heart attack, stroke, heart failure and death due to cardiovascular disease when compared to a standard treatment approach, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Tirzepatide improves heart health and function in obese HFpEF patients

In the international SUMMIT trial, adults with heart failure preserved ejection fraction (HFpEF) and obesity taking tirzepatide for up to 3 years had a reduced combined risk of worsening heart failure events and cardiovascular death, and improved health status and physical function in comparison to participants taking placebo, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Anticoagulants fail to reduce cognitive decline in younger adults with AFib

Prescribing anti-clotting medications to adults younger than age 65 who have atrial fibrillation (AFib) but no other risk factors for stroke did not reduce the risk of cognitive decline, stroke or transient ischemic attack (TIA), according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Ablation may offer better outcomes than medication for ventricular tachycardia

Ablation, a procedure to treat abnormal electrical short circuits caused by a heart attack and is usually reserved for patients who do not improve with medication, may be a better first-line treatment for heart attack survivors experiencing dangerous rapid heartbeat episodes, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

SGLT2 inhibitor canagliflozin shown to improve kidney oxygenation in diabetes patients

Type 2 diabetes can lead to diabetic kidney disease, but a class of drugs that cause the kidneys to remove glucose through urine has been gaining attention.

18 Nov 2024

NSAIDs raise bleeding risk in patients taking blood thinners

People who take an anticoagulant medicine double their risk of an internal bleed if they take a type of painkiller called a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or naproxen, according to research published in the European Heart Journal [1] today (Monday).

18 Nov 2024

AI algorithm accurately detects early-stage metabolic-associated steatotic liver disease

Liver disease, which is treatable when discovered early, often goes undetected until late stages, but a new study revealed that an algorithm fueled by artificial intelligence can accurately detect early-stage metabolic-associated steatotic liver disease (MASLD) by using electronic health records.

18 Nov 2024

Monash researchers develop model to tackle weight stigma in pregnancy and beyond

People with larger bodies commonly face a pervasive, resilient form of social stigma, often facing discrimination in the workplace as well as in educational and healthcare settings.

18 Nov 2024

New clinical trial offers hope for patients with rare immune disease IgG4-RD

A team led by Mass General Brigham researchers demonstrated that inebilizumab reduced the risk of symptoms by 87% in patients with the rare affliction known as immunoglobulin G4–related disease (IgG4-RD)

18 Nov 2024

Neoantigen DNA vaccines improve survival and immunity in triple-negative breast cancer patients

A new phase 1 trial demonstrates the safety and effectiveness of personalized neoantigen DNA vaccines, showing promising immune responses and improved recurrence-free survival in high-risk triple-negative breast cancer patients.

17 Nov 2024

Zinc deficiency linked to increased risk of lung infection

Dietary zinc deficiency promotes lung infection by Acinetobacter baumannii bacteria - a leading cause of ventilator-associated pneumonia, according to a new study published Nov. 15 in the journal Nature Microbiology.

15 Nov 2024

Pulses of light show promise in controlling seizures

In what could one day become a new treatment for epilepsy, researchers at UC San Francisco, UC Santa Cruz and UC Berkeley have used pulses of light to prevent seizure-like activity in neurons.

15 Nov 2024

Antiseizure medications during pregnancy linked to neurodevelopmental risks in children

Children born to mothers who take antiseizure medications to manage seizures and psychiatric conditions during pregnancy may face increased risks of neurodevelopmental conditions, according to new data from researchers at Drexel's Dornsife School of Public Health.

15 Nov 2024

Specific redox protein identified as a critical regulator of ferroptosis

Researchers at Helmholtz Munich, in collaboration with colleagues at Tohoku University, have identified a specific redox protein as a critical regulator of ferroptosis - a form of regulated oxidative cell death.

15 Nov 2024