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COMBINEDBrain and MUSC join forces to launch pediatric CNS biorepository

COMBINEDBrain, a leader in advancing translational neuroscience research, and the Medical University of South Carolina (MUSC), one of the nation's premier academic health centers, are excited to announce a strategic partnership to establish a cutting-edge biorepository for pediatric central nervous system (CNS) tissue and biofluids.

7 Oct 2025

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it's widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine.

7 Oct 2025

Whole genome sequencing may guide care for thousands of breast cancer patients

Whole genome sequencing offered to breast cancer patients is likely to identify unique genetic features that could either guide immediate treatment or help match patients to clinical trials for over 15,000 women a year, say scientists at the University of Cambridge.

7 Oct 2025

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer's disease in mice.

6 Oct 2025

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

The body's tissues can get injured in many ways, but while some injuries heal perfectly, others don't heal at all. A cut in the skin, for example, usually heals all on its own, while internal organs, such as the heart after a heart attack or the kidney after an acute injury, remain damaged, leading to diminished function.

6 Oct 2025

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Researchers discuss the effects of azelastine nasal spray on the rate of SARS-CoV-2 infection as compared to placebo.

6 Oct 2025

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third of the adult population. This disorder is characterized by the accumulation of fat in liver cells, which has severe liver consequences and is also associated with a high mortality rate from cardiovascular disease.

6 Oct 2025

Large-scale analysis offers insights into sporadic nature of chikungunya virus outbreaks

The symptoms come on quickly - acute fever, followed by debilitating joint pain that can last for months. Though rarely fatal, the chikungunya virus, a mosquito-borne illness, can be particularly severe for high-risk individuals, including newborns and older adults.

6 Oct 2025

New ultrasound technique used to stimulate multiple locations in the brain simultaneously

For the first time, a new ultrasound technique allows researchers to stimulate multiple locations in the brain simultaneously.

3 Oct 2025

AI serves as a tool to fight drug resistance and accelerate new antibiotic development

Researchers at McMaster University and the Massachusetts Institute of Technology (MIT) have made two scientific breakthroughs at once: they not only discovered a brand-new antibiotic that targets inflammatory bowel diseases (IBD), but also successfully used a new type of AI to predict exactly how the drug works. To their knowledge, this a global first for the AI.

3 Oct 2025

VR technology proves better than anti-anxiety meds in coronary angiography

Patients undergoing coronary angiography often experience anxiety both before and during the procedure, often treated by the administration of anti-anxiety medications. A new analysis being presented at the American College of Cardiology (ACC) Middle East 2025 Together with 16th Emirates Cardiac Society Conference found virtual reality (VR) effectively reduced anxiety during the procedure and had more stable vital signs than patients receiving standard care.

3 Oct 2025

New insights into how antimicrobial peptides kill bacterial cells

New research into antimicrobial peptides, small chains of amino acids able to damage bacterial cells, shows why some peptides are more effective at doing that and also why some cells are more vulnerable.

2 Oct 2025

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

Discover how Bruker and the University of Manchester joined forces to discover more on the dynamics of complex protein.

From Bruker BioSpin Group 2 Oct 2025

The neurological complexity of Mamba snake venoms uncovered

A breakthrough study at The University of Queensland has discovered a hidden dangerous feature in the Black Mamba one of the most venomous snakes in the world.

30 Sep 2025

Harnessing “DNA surgery” to develop therapeutic medicines for genetic liver and heart diseases

Genome editing is increasingly recognized as a leading frontier in biomedical research and an essential driver of healthcare innovation.

30 Sep 2025

Automated machine learning tool scans social media to detect health product risks

A new artificial intelligence tool can scan social media data to discover adverse events associated with consumer health products, according to a study published September 30th in the open-access journal PLOS Digital Health by John Ayers of the University of California, San Diego, U.S., and colleagues.

30 Sep 2025

Cannabis extract eases chronic back pain and improves quality of life in major clinical trial

A phase 3 trial in Nature Medicine found that a full-spectrum Cannabis sativa extract (VER-01) significantly reduced chronic low back pain and improved sleep and function compared with placebo. The extract was safe, well-tolerated, and showed no signs of abuse or dependence, with benefits maintained over long-term treatment.

30 Sep 2025

Controversy surrounding Covid-19 vaccination during pregnancy

Whether or not those who are pregnant should take a Covid-19 vaccine to protect themselves and their infants became more controversial in May, when three top U.S. health officials – Health and Human Services (HHS) Secretary Robert F. Kennedy Jr., National Institutes of Health Director Jay Bhattacharya, and Food and Drug Administration director Marty Makary – announced that the Centers for Disease Control and Prevention (CDC) immunization schedule will no longer recommend it "for healthy children and healthy pregnant women."

30 Sep 2025

Intranasal adrenaline can be as effective as the EpiPen

Instead of stabbing yourself, or someone else, in the thigh with a needle to deliver a dose of adrenaline to counter anaphylactic shock, would it not be easier to use a nasal spray instead?

30 Sep 2025

Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling

The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, which are closely associated with various diseases including neurodegenerative diseases and cancers.

30 Sep 2025

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Efficacy News and Research

COMBINEDBrain and MUSC join forces to launch pediatric CNS biorepository

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

Whole genome sequencing may guide care for thousands of breast cancer patients

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

Azelastine nasal spray prevents COVID-19 and rhinovirus infections

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Large-scale analysis offers insights into sporadic nature of chikungunya virus outbreaks

New ultrasound technique used to stimulate multiple locations in the brain simultaneously

AI serves as a tool to fight drug resistance and accelerate new antibiotic development

VR technology proves better than anti-anxiety meds in coronary angiography

New insights into how antimicrobial peptides kill bacterial cells

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

The neurological complexity of Mamba snake venoms uncovered

Harnessing “DNA surgery” to develop therapeutic medicines for genetic liver and heart diseases

Automated machine learning tool scans social media to detect health product risks

Cannabis extract eases chronic back pain and improves quality of life in major clinical trial

Controversy surrounding Covid-19 vaccination during pregnancy

Intranasal adrenaline can be as effective as the EpiPen

Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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