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Experimental drug kills aggressive breast cancer by toxic fat buildup

An experimental drug targeting triple-negative breast cancer overwhelms cancer cells with toxic fats, according to new tests on human-derived tumors in mice.

22 Apr 2026

GP nurses could deliver effective sleep treatments

A new Flinders University study shows that nurses working in general practice could play a major role in improving access to sleep‑health treatment, but only if patients and general practice staff are involved in designing these services.

22 Apr 2026

Gut microbiome characteristics predict treatment response in IBS-D patients

In a new study published in Clinical Gastroenterology and Hepatology, the low FODMAP diet and the antibiotic rifaximin provided similar and significant relief for patients with irritable bowel syndrome with diarrhea (IBS-D).

22 Apr 2026

Availability of HIV treatments contributed to a resurgence in syphilis

A study in Health Economics uncovered an unintended consequence of a major medical breakthrough: while the availability of HIV treatments in the late 1990s dramatically improved survival, they also contributed to a resurgence in syphilis, a sexually transmitted infection.

22 Apr 2026

Survey of families suggests high risks for electroconvulsive therapy

Electroconvulsive therapy (ECT), which involves passing electricity through the brain under general anesthesia to cause a seizure, usually between six and twelve times, is used to varying degrees around the world for patients with depression and other mental conditions.

22 Apr 2026

Immunotherapy drug helps bladder cancer patients avoid major organ removal

A drug that helps the immune system find cancer cells also helps patients avoid having their bladders surgically removed (cystectomy), a new study shows.

22 Apr 2026

Rapid blood infection test fails to improve survival

Rapid antimicrobial susceptibility testing for gram-negative blood infections shows no improvement in clinical outcomes compared to standard testing methods.

22 Apr 2026

Study shows older lung recipients can achieve outcomes comparable to youth

Today at the International Society for Heart and Lung Transplantation (ISHLT) 46th Annual meeting and Scientific Sessions, transplant specialists Brian Keller, MD, PhD, and Thomas Egan, MD debated an ethically fraught question: How old is too old for a lung transplant?

22 Apr 2026

Tumor immune cell patterns predict melanoma immunotherapy response

A new UCLA Health Jonsson Comprehensive Cancer Center study suggests that the way immune cells are organized inside melanoma tumors may help researchers better understand which patients will benefit from combination immunotherapy after standard anti-PD-1 treatment stops working - and which may not.

22 Apr 2026

New molecule weakens glioblastoma and enhances immune response

A team of researchers from Brown University Health and Brown University has uncovered an important clue in the fight against glioblastoma, the most common and aggressive form of brain cancer in adults.

21 Apr 2026

New guideline recommends combined therapies for chronic insomnia treatment

A new clinical practice guideline from the American Academy of Sleep Medicine provides evidence‑based recommendations on the combined use of behavioral‑psychological and pharmacological therapies to treat chronic insomnia disorder in adults.

21 Apr 2026

Study links cognitive worries in Parkinson’s to anxiety and depression

For many individuals living with Parkinson's disease and those in its "prodromal" or early stages before movement impairment, there is a distressing gap between how they feel their brain is working and what clinical tests show.

21 Apr 2026

CAR-PRISM trial reports promising results in high-risk smoldering multiple myeloma

Results of the single-center, phase 2 CAR-PRISM (PRecision Intervention Smoldering Myeloma) clinical trial, the first to investigate Chimeric Antigen Receptor (CAR) T-cell therapy in patients with high-risk smoldering multiple myeloma, showed that all 20 patients were negative for minimal residual disease (MRD) within two months of treatment and remained MRD-negative after a median of 15.3 months of follow-up, and none experienced high-grade side effects, according to results presented at the AACR Annual Meeting 2026, held April 17-22, in San Diego, Calif.

21 Apr 2026

Early myocarditis onset after immunotherapy linked to higher fatality risk

Patients who developed myocarditis within the first month of receiving immune checkpoint inhibitor therapy were more likely to die of myocarditis, and myocarditis-specific fatality was more common in patients who experienced co-occurring myositis and myasthenia gravis, according to results from a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

21 Apr 2026

Common gene in axolotls, mice and zebrafish may unlock human limb regrowth

Investigating a common gene in three very different species – axolotls, mice and zebrafish – scientists have discovered the potential for a novel gene therapy aimed at eventually regrowing limbs in humans, according to new research published this week.

21 Apr 2026

Atelerix launches STORganoid cryo-free preservation solution for complex 3D cell models

Atelerix, a biotech company revolutionizing cell preservation and biological transport with its pioneering hydrogel encapsulation technology, today announced the launch of STORganoid™, an ambient-temperature preservation solution for organoids and spheroids.

From Atelerix Ltd 21 Apr 2026

DNA methylation "fingerprints" identify primary sites in metastatic cancers

A machine learning model analyzing CpG-based DNA methylation accurately predicted the origin of many different cancer types in patients with cancers of unknown primary (CUP), according to research presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

21 Apr 2026

Early genomic testing prevents years of inconclusive visits for pediatric patients

For many families, eight years of uncertainty meant repeated specialist visits, inconclusive genetic tests and the growing fear that a clear answer might never come. For nearly half of the children enrolled in the Telethon Undiagnosed Disease Program (TUDP), that wait is now over.

21 Apr 2026

Phase I NSCLC trials shrink and cluster in major U.S. cities

Between 2020 and 2024, the number of unique sites in the United States where phase I clinical trials for non-small cell lung cancer (NSCLC) were conducted decreased by 44% and became increasingly concentrated at the top 20 highest‑volume clinical trial sites largely located in major cities, according to results presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

21 Apr 2026

Muscle energy recovery may explain fatigue in cancer survivors

Even apparently healthy cancer survivors often complain of extreme fatigue. They have finished treatment, the scans are clear, but they feel hollowed out, unable to walk to the mailbox or stay awake through dinner.

21 Apr 2026