Aging News and Research

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White matter alterations connect coronary artery disease to cognitive decline

Individuals with coronary artery disease (CAD) - a constricting or blocking of blood vessels feeding the heart - face increased risks of strokes, cognitive impairment and dementia. However, the link between CAD and cognitive function is not fully understood.

25 Nov 2025

Long-term calorie restriction can slow cellular markers of brain aging

As the brain ages, cells in the central nervous system experience metabolic dysfunction and increased oxidative damage.

25 Nov 2025

Infection-related hospital stays linked to higher risk of developing dementia

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled "Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis."

25 Nov 2025

Polyamines restore gut regeneration in aging mice

With aging, the intestine gradually loses its ability to regenerate after damage. An international research team involving the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena and the University of Turin has now found that polyamines, small molecules produced naturally in the body, can play a decisive role in this process.

25 Nov 2025

Neuroscientists detect five broad phases of brain structure in the average human life

Neuroscientists at the University of Cambridge have identified five "major epochs" of brain structure over the course of a human life, as our brains rewire to support different ways of thinking while we grow, mature, and ultimately decline.

25 Nov 2025

Sex-specific changes in gluteus maximus shape linked to aging and metabolic health

The shape of the gluteus maximus muscle in the buttocks changes in different ways with aging, lifestyle, frailty, osteoporosis and type 2 diabetes, and these changes differ between women and men, according to new research being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

25 Nov 2025

Scientists reverse aging in blood stem cells by restoring lysosome function

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

24 Nov 2025

New analysis shows one in two people in the U.S. live with neurological conditions

One in two people in the United States, just over half of the population, is affected by a neurological disease or disorder, according to a new systematic analysis by the American Academy of Neurology and the Institute for Health Metrics and Evaluation published on November 24, 2025, in the journal JAMA Neurology.

24 Nov 2025

New study links untreated sleep apnea to higher Parkinson’s disease risk

New research reveals that people with untreated obstructive sleep apnea have a higher risk of developing Parkinson's disease. However, they can significantly reduce the risk by improving the quality of their sleep by using continuous positive airway pressure, or CPAP.

24 Nov 2025

Can diet calm early memory problems? Anti-inflammatory Mediterranean eating shows promise

Older women who follow a strongly anti-inflammatory Mediterranean diet report far fewer subjective memory complaints than those who do not. The AnMED pattern outperforms both traditional Mediterranean and MIND diets, showing a clear advantage for protecting early cognitive symptoms.

24 Nov 2025

Most Medicaid patients do not receive life-saving drugs for opioid use disorder

A US study of more than a million Medicaid enrollees, newly diagnosed with opioid use disorder (OUD), finds most – nearly seven in 10 – are not receiving access to potentially life-saving drugs within six months.

24 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Does coffee truly boost memory and focus or is it all hype?

Coffee’s bioactive compounds, especially caffeine, show potential cognitive, neuroprotective, and neuroplasticity benefits across animal and human studies. However, most findings are observational, mechanisms remain uncertain, and optimal intake is still unclear.

23 Nov 2025

Masturbation could improve mood and sleep during menopause

This study found that about one in five perimenopausal and postmenopausal women experienced measurable symptom relief from masturbation, particularly for sleep and mood. Nearly half said they would consider using it for symptom relief if their doctor recommended it, although many had never discussed it with a clinician.

23 Nov 2025

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in each cell.

22 Nov 2025

New method can stop or reverse the decline of cellular energy production

Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production - a finding that could have revolutionary effects across medicine.

22 Nov 2025

Astrocyte-driven approach shows potential to reverse cognitive decline in Alzheimer’s

Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer's disease and preserves cognitive function.

21 Nov 2025

New report outlines skills needed to thrive in an era of extended lifespans

To take maximum advantage of the added days, months, and years people enjoy because of modern health care and healthier habits, they need to achieve competency in several areas necessary for longer lives, states a new Gerontological Society of America report, "Health and Wealth in the Era of Longevity."

21 Nov 2025

Changes in brain fats play a key role in Alzheimer's development and progression

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

20 Nov 2025

Searches for “Ozempic face” surge as people look for filler-based solutions

Public interest in “Ozempic face” rose sharply from 2022 to 2025, mirrored by increased searches for nonsurgical facial filler procedures. Surgical terms showed neutral or negative associations, indicating consumers are primarily exploring filler-based solutions for GLP-1RA-related facial volume loss.

20 Nov 2025