Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia.

22 Dec 2022

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

22 Dec 2022

Botox treatment may lessen anxiety

Botox, or Botulinum toxin, a medication derived from a bacterial toxin, is commonly injected to ease wrinkles, migraines, muscle spasms, excessive sweating and incontinence.

22 Dec 2022

Physicians reveal main risk factors for sudden death from a colloid cyst

RUDN University physicians investigated known cases of sudden death from a colloid cyst. After analyzing the data, the authors named the main risk factors and told what to look for. The results are published in the Journal of Clinical Neuroscience.

22 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

Study helps understand why some people have persistent smell loss after COVID-19 infection

The reason some people fail to recover their sense of smell after COVID-19 is linked to an ongoing immune assault on olfactory nerve cells and an associated decline in the number of those cells, a team of scientists led by Duke Health report.

21 Dec 2022

Analysis highlights substantial cost savings by reducing sedation for pediatric brain MRI examinations

Findings from an accepted manuscript published in ARRS' American Journal of Roentgenology have highlighted potentially substantial cost savings by reducing the use of sedation for pediatric brain MRI examinations.

21 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

Women who have cluster headache are more affected in their daily lives, shows study

Cluster headache, sometimes known as "suicide headache", have been described as a predominantly male disease.

21 Dec 2022

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

A collaborative team, which includes scientists from the Terasaki Institute for Biomedical Innovation, University of Illinois Chicago, and Pohang University of Science and Technology has elucidated some key points on how the generation of cartilage in the joints is facilitated and how alternative bone formation can be avoided.

21 Dec 2022

Research links mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells

A research team led by the University of California, Irvine has linked the mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells that are caused by changes in metabolism.

21 Dec 2022

Study explores cellular alterations in six distinct neurodegenerative diseases

A perplexing range of neurodegenerative diseases are known to attack distinct regions of the brain, causing severe cognitive and motor deficit.

21 Dec 2022

Improving neuroplasticity hastens hearing among cochlear implant recipients

Kick-starting the brain's natural ability to adjust to new circumstances, known as neuroplasticity, improves how effectively a cochlear implant can restore hearing loss, a new study in deaf rats shows.

21 Dec 2022

Study provides insights into the coordinated dance of nerve and vascular cells

Nerve cells need a lot of energy and oxygen. They receive both through the blood. This is why nerve tissue is usually crisscrossed by a large number of blood vessels.

21 Dec 2022

CARxALL clinical trial approved to evaluate CAR-T technology for patients with T-cell leukemia subtype

The Spanish Agency of Medicines and Medical Products (AEMPS) has approved the CARxALL clinical trial led by the company OneChain Immunotherapeutics (OCI).

21 Dec 2022

Using an AI tool for early identification of Alzheimer's and related dementias in primary care

Rising to meet the formidable challenge of the timely diagnosis of dementia, research scientists from Regenstrief Institute, IUPUI and the medical schools of Indiana University and University of Miami are conducting the Digital Detection of Dementia study, a real-world evaluation of the use of an artificial intelligence (AI) tool they developed for early identification of Alzheimer's disease and related dementias in primary care, the setting where most adults receive healthcare.

21 Dec 2022

Brief roundup of research done by experts at UCLA Health

Below is a brief roundup of news and story ideas from the experts at UCLA Health.

21 Dec 2022

Exposure to blue-green algae toxin shown to wreak havoc on gut bacteria and cause liver damage

Exposure to a specific type of blue-green algae toxin known as cylindrospermopsin has shown to wreak havoc on gut bacteria and an increased probability of irritable bowel syndrome, inflammatory bowel disease, celiac disease, type 1 diabetes, obesity and inflammation of the liver – a precursor to liver cancer – according to a study led by the University of California, Irvine.

20 Dec 2022

Study highlights the lag in screening and treatment of osteoporosis

A new perspective article published in the Lancet Diabetes & Endocrinology has highlighted that screening and treatment of osteoporosis lags behind other diseases, resulting in significant morbidity, mortality, and economic costs.

20 Dec 2022

Brain News and Research

Further Reading

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

Botox treatment may lessen anxiety

Physicians reveal main risk factors for sudden death from a colloid cyst

Impact of epigenetics on the clinical management of cancer patients

Study helps understand why some people have persistent smell loss after COVID-19 infection

Analysis highlights substantial cost savings by reducing sedation for pediatric brain MRI examinations

Recapitulating early stages of the human body plan in a dish

Women who have cluster headache are more affected in their daily lives, shows study

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

Research links mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells

Study explores cellular alterations in six distinct neurodegenerative diseases

Improving neuroplasticity hastens hearing among cochlear implant recipients

Study provides insights into the coordinated dance of nerve and vascular cells

CARxALL clinical trial approved to evaluate CAR-T technology for patients with T-cell leukemia subtype

Using an AI tool for early identification of Alzheimer's and related dementias in primary care

Brief roundup of research done by experts at UCLA Health

Exposure to blue-green algae toxin shown to wreak havoc on gut bacteria and cause liver damage

Study highlights the lag in screening and treatment of osteoporosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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