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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Study uncovers previously unknown genetic cause of late-onset cerebellar ataxia

A new study published on Dec. 14, 2022 in the New England Journal of Medicine reports the identification of a previously unknown genetic cause of a late-onset cerebellar ataxia, a discovery that will improve diagnosis and open new treatment avenues for this progressive condition.

15 Dec 2022

Study finds altered spontaneous brain activity in people with Down syndrome

Researchers of the Faculty of Psychology, the Institute of Neurosciences and the Institute of Complex Systems of the University of Barcelona have identified, using functional magnetic resonance techniques, differences in the spontaneous activity of the brain in a resting state in people with Down syndrome (DS) compared to the general population. Also, these variations could be related to cognitive skills.

15 Dec 2022

Four genetic mutations linked to progressive multifocal leukoencephalopathy

New research has confirmed a strong link between four genetic mutations and progressive multifocal leukoencephalopathy (PML), a rare but often fatal brain infection that can be triggered by dozens of FDA-approved drugs.

14 Dec 2022

Study reveals limited effects of longevity treatments on the aging process

Three approaches with a reputation for slowing aging processes have proven largely ineffective. For their study, researchers developed a new method to measure aging, which accounts for the complexity of aging in organisms.

14 Dec 2022

Flexible assemblies of nerve cells appear to be key to successful episodic memory

For the first time, scientists have recorded human nerve cells firing together in flexible assemblies, a process that appears necessary to successfully encode long-term memories, a study led by UT Southwestern researchers reports.

14 Dec 2022

Subcutaneous fat protects against brain inflammation in females

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

14 Dec 2022

The therapeutic effects and safety of psychedelics

Psychedelics are reported to have rapid-onset and long-lasting therapeutic benefits after a single or few doses.

14 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

Study seeks to look for a better treatment for endometriosis

Up to 15% of women of reproductive age in the United States suffer from endometriosis, a condition characterized by pelvic pain, menstrual cramps and infertility.

14 Dec 2022

U-M leads multi-university partnership that aims to predict cognitive fatigue in individuals

Researchers at the University of Michigan are leading a multi-university partnership that aims to understand and predict cognitive fatigue in individuals.

13 Dec 2022

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Structural racism has not only psychosocial but also biological consequences. Discrimination has been shown to contribute to mental and physical disorders including obesity, depression, and addiction, but the biological pathways from a social experience to its impacts on the body remain unknown.

13 Dec 2022

Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by the organism.

13 Dec 2022

Study: Exercise, mindfulness training, or both do not improve cognitive performance in seniors

Older adults work with exercise trainers as part of a study to see whether exercise, mindfulness training, or both might improve cognitive performance in seniors.

13 Dec 2022

Virginia Tech researchers receive three grants to study the effects of ultra-processed foods

Scientists in the Virginia Tech College of Agriculture and Life Sciences are investigating the effects of ultra-processed foods on the human body using a variety of research tools.

13 Dec 2022

Report makes recommendations clarifying the ethics and oversight of chimeric research

A new report on the ethics of crossing species boundaries by inserting human cells into nonhuman animals – research surrounded by debate – makes recommendations clarifying the ethical issues and calling for improved oversight of this work.

13 Dec 2022

RNA-targeting CRISPR technology alleviates disease-related phenotypes in Huntington’s models

Huntington's disease (HD) is a neurological disorder that causes progressive loss of movement, coordination and cognitive function.

12 Dec 2022

Using mobile devices to calm upset preschoolers could lead to worse behavior challenges down the road

It's a scene many parents have experienced – just as they're trying to cook dinner, take a phone call or run an errand, their child has a meltdown.

12 Dec 2022

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

An international research team led by Dr Ana Guadaño at the Alberto Sols Biomedical Research Institute (IIBM, a combined CSIC-UAM center) and involving the Complutense University of Madrid (UCM), used CRISPR gene editing techniques to incorporate into the mice a mutation of the MCT8 protein responsible for transporting thyroid hormones to the interior of the cell.

12 Dec 2022

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Amyloid plaques — protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, early-onset Alzheimer's, according to research funded by the National Institutes of Health.

12 Dec 2022

Brain News and Research

Further Reading

Study uncovers previously unknown genetic cause of late-onset cerebellar ataxia

Study finds altered spontaneous brain activity in people with Down syndrome

Four genetic mutations linked to progressive multifocal leukoencephalopathy

Study reveals limited effects of longevity treatments on the aging process

Flexible assemblies of nerve cells appear to be key to successful episodic memory

Subcutaneous fat protects against brain inflammation in females

The therapeutic effects and safety of psychedelics

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Study seeks to look for a better treatment for endometriosis

U-M leads multi-university partnership that aims to predict cognitive fatigue in individuals

Study examines the role of brain-gut microbiome system in discrimination-related health issues

Study uncovers a new immune culprit in Alzheimer’s disease

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Study: Exercise, mindfulness training, or both do not improve cognitive performance in seniors

Virginia Tech researchers receive three grants to study the effects of ultra-processed foods

Report makes recommendations clarifying the ethics and oversight of chimeric research

RNA-targeting CRISPR technology alleviates disease-related phenotypes in Huntington’s models

Using mobile devices to calm upset preschoolers could lead to worse behavior challenges down the road

CRISPR/Cas9-engineered avatar mouse model of rare disease paves the way for targeted therapy

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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