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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Pandemic-related stressors have physically altered teens’ brains, study shows

A new study from Stanford University suggests that pandemic-related stressors have physically altered adolescents' brains, making their brain structures appear several years older than the brains of comparable peers before the pandemic.

1 Dec 2022

HU begins human trial for promising treatment to reverse paralysis and language disorder after stroke

Hiroshima University started the human trial for a promising treatment that offers hope in potentially reversing paralysis and language disorder after moderate to severe stroke using therapeutically superior mesenchymal stem cells (MSCs) derived from the cranial bone.

1 Dec 2022

Scientists discover new potential mechanism for vision loss

Visual cells in the human retina may not simply die in some diseases, but are mechanically transported out of the retina beforehand.

1 Dec 2022

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

Past social trauma is encoded by a population of stress/threat-responsive brain cells that become hyperactivated during subsequent interaction with non-threatening social targets. As a consequence, previously rewarding social targets are now perceived as social threats, which promotes generalized social avoidance and impaired social reward processing that can contribute to psychiatric disorders, according to a study conducted by researchers at the Brain and Body Research Center at Mount Sinai and published November 30 in Nature.

30 Nov 2022

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

A change in the DNA code (mutation) of a gene that plays a key role in the brain's immune defenses may prevent related cells from clearing away protein-filled clumps, a new study in mice shows.

30 Nov 2022

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that high glucose impairs the antitumor activity of immune effector γδ-T cells, which contributes to the increased cancer risk in diabetes and that metabolic reprogramming by glucose control may improve the antitumor activity of γδ-T cells.

30 Nov 2022

Study reveals key details of how DREADD technology highjacks neuronal activity

Understanding of how neuronal activity modulates brain function is a key first step towards creating more effective drugs to treat a variety of neuropsychiatric illnesses, including depression, anxiety, schizophrenia, substance abuse, epilepsy, and others.

30 Nov 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Women having a higher BMI more likely to experience long Covid

Overweight women are more likely to experience symptoms of long Covid according to new research from the University of East Anglia.

30 Nov 2022

Removal of cilia from the brain's striatum impairs time perception and judgment, study finds

Researchers at the University of California, Irvine have discovered that removal of cilia from the brain's striatum region impaired time perception and judgment, revealing possible new therapeutic targets for mental and neurological conditions including schizophrenia, Parkinson's and Huntington's diseases, autism spectrum disorder, and Tourette syndrome.

30 Nov 2022

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Studying mice has filled encyclopedias with breakthrough medical discoveries. But when it comes to brain cancers, the little rodents have long exhibited fundamental limitations.

30 Nov 2022

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Less than 20% of diagnosed breast cancers are designated "triple-negative," lacking three types of receptors often found in other breast cancer types.

30 Nov 2022

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

A new study led by researchers from the University of Barcelona shows that wasteosomes - structures that act as containers for brain waste products - indicate a malfunction of the glymphatic system, a recently discovered system that is an important brain-cleaning mechanism.

30 Nov 2022

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

A new study links a gene concentrated in the brain's cleanup cells, known as microglia, to the inflammation that has increasingly emerged as a key mechanism contributing to Alzheimer's disease.

30 Nov 2022

New study questions the perception that autistic individuals experience less pain

People with autism have normal pain thresholds but increased sensitivity to painful stimuli, concludes a study in PAIN, the official publication of the International Association for the Study of Pain.

30 Nov 2022

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

In our cells, the language of DNA is written, making each of us unique. A tandem repeat occurs in DNA when a pattern of one or more nucleotides – the basic structural unit of DNA coded in the base of chemicals cytosine (C), adenine (A), guanine (G) and thymine (T) – is repeated multiple times in tandem. An example might be: CAG CAG CAG, in which the pattern CAG is repeated three times.

30 Nov 2022

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers.

30 Nov 2022

Brain News and Research

Further Reading

Pandemic-related stressors have physically altered teens’ brains, study shows

HU begins human trial for promising treatment to reverse paralysis and language disorder after stroke

Scientists discover new potential mechanism for vision loss

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

INPP5D gene plays key role in enabling microglial cells to prevent plaque buildup

Study provides novel therapeutic targets for enhancing the antitumor immunity of γδ-T cells in diabetes

Study reveals key details of how DREADD technology highjacks neuronal activity

SARS-CoV-2 can cause hyperglycemia in cats

Women having a higher BMI more likely to experience long Covid

Removal of cilia from the brain's striatum impairs time perception and judgment, study finds

Human fetal cerebellar cell atlas reveals the origin of aggressive medulloblastomas

Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer

Study reveals wasteosomes as markers of chronic glymphatic system insufficiency

Research findings may offer a new potential therapeutic target for Alzheimer’s disease

New study questions the perception that autistic individuals experience less pain

Research finds higher rate of rare tandem repeats in the genomes of individuals with schizophrenia

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Cannabidiol and the shifting perspective of epilepsy drug discovery

Understanding the genetics of healthy brain cells to target vulnerabilities in glioblastomas

Researchers illuminate the brain processes that support the emergent meaning of combined words

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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