Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Cancer is the world's second deadliest disease which contributes towards the fatality of over 10 million people per year.

3 Apr 2021

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

Collaborative teams that include Southwest Research Institute staff received two of six recently awarded San Antonio Medical Foundation (SAMF) bioscience grants. SwRI, in collaboration with UT Health San Antonio and University Health System, received a nearly $200,000 grant to develop machine learning algorithms for cancer detection.

31 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

New SARS-CoV-2 genome variants identified in US mink

Researchers in Canada have discovered two novel variants in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gene sequences collected from mink in the United States.

28 Mar 2021

Scientists reveal salivary gland cells as sites of COVID-19 infection

Scientists have shown that SARS-CoV-2, the virus that causes COVID-19, can infect specific cells in the salivary gland in the mouth.

25 Mar 2021

Researchers characterize a potential therapeutic target to weaken COVID-19

When invaded by a virus, our body cells launch an alert to neighboring cells to increase their antiviral defenses to prevent the infection from spreading.

24 Mar 2021

New method for scDNA sequencing provides insights into breast cancer evolution

vercoming previous technical challenges with single-cell DNA (scDNA) sequencing, a group led by researchers at The University of Texas MD Anderson Cancer Center has developed a novel method for scDNA sequencing at single-molecule resolution.

24 Mar 2021

How could AI be used to predict infection outcomes?

Professor Frankel speaks to News-Medical about his latest research that investigated whether AI could be used to predict infection outcomes.

23 Mar 2021

SARS-CoV-2 infection is circadian

An international team of researchers has found that angiotensin-converting enzyme 2 (ACE2) levels in lung cells vary over the day, affecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The virus entry and replication in the lung cells also have a rhythmic cycle, suggesting circadian processes can affect the virus's life cycle.

22 Mar 2021

New book explains the functional aspects of melanogenesis and related disorders

The Vertebrate Pigmentary System: From pigment cells to disorders provides readers with fundamental knowledge of the structural and functional aspects of vertebrate pigment cells - melanophores and melanocytes - from their origin to different stages of development to related diseases.

22 Mar 2021

Newly discovered enzyme on deadly fungus may be the key to fight fungal infection

Aspergillus fumigatus kills as many people as malaria and tuberculosis, but is less known. It is found "everywhere", for example in the soil or in our compost, but is not normally dangerous to healthy people.

20 Mar 2021

Scientists identify address codes in odorant receptor proteins

A team of scientists led by Dietmar Krautwurst from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now identified address codes in odorant receptor proteins for the first time.

17 Mar 2021

Adequate reimbursement for molecular diagnostic tests can improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today released the results of its qualitative and quantitative "Analysis of Professional Work Effort in Molecular Test Interpretation Report."

17 Mar 2021

Empiric Logic collaborates with UCD to develop novel genomics data protection methodology

Empiric Logic, an Irish bioinformatics SaaS (software-as-a-service) start-up, today announced that is has secured €85,000 in grant funding, under Enterprise Ireland's Innovation Partnership Programme, to develop a novel genomics data protection methodology in collaboration with University College Dublin.

15 Mar 2021

Deforestation in the Amazon increases diversity of antibiotic-resistant bacteria

In Brazil, a study conducted by researchers affiliated with the University of São Paulo (USP) and collaborators showed that deforestation in the Amazon causes an increase in the diversity of antibiotic-resistant bacteria.

12 Mar 2021

SARS-CoV-2 UK variant could soon be dominant in Switzerland

Researchers at the Swiss Institute of Bioinformatics estimate that the B.1.1.7 variant may be dominant in Switzerland by March.

10 Mar 2021

Scientists study seven human coronavirus envelope proteins using topology prediction and molecular modeling

A new study by researchers at the University of the Western Cape aimed to determine why some coronaviruses are more virulent than others. The team speculates that the increased flexibility of the PDZ-binding motif (PBM) of SARS-CoV, MERS-CoV, and SARS22 CoV-2 to be more flexible than the PBM of hCoVs 229E, NL63, OC43, and HKU1.

9 Mar 2021

Multisystem intervention could potentially prevent or reverse frailty, research shows

Physicians understand frailty as a dysregulation among multiple systems in the body that make it less resilient and unable to recover completely when faced with a physical challenge such as injury or illness.

8 Mar 2021

Study offers new clues to how night shift work increases cancer risk

New clues as to why night shift workers are at increased risk of developing certain types of cancer are presented in a new study conducted at Washington State University Health Sciences Spokane.

8 Mar 2021

Interaction between LDL cholesterol and PRS can predict risk of heart attack

Allelica, a leading genomics software company specializing in developing polygenic risk scores (PRS) for personalised medicine, today announced publication of a study in Circulation (Vol. 143, Issue 10) showing that the effect of LDL cholesterol on a person's risk of having a heart attack depends on their genes.

8 Mar 2021