Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Panakeia launches AI-driven PANProfiler Colon for rapid cancer profiling

Panakeia (“the Company”), a pioneer in AI-driven multi-omic biomarker profiling, today announces the launch of PANProfiler Colon, an AI-driven software solution for profiling of Microsatellite instability (MSI) and mismatch repair deficiency (dMMR) entirely digitally and directly from Hematoxylin and Eosin (H&E)-stained images of colon cancer tissue samples.

15 Jan 2025

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Spear Bio Inc., a biotechnology company pioneering next-generation ultra-sensitive immunoassays, today announced that its pTau 217 blood test has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA).

From Spear Bio 15 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation.

15 Jan 2025

No short-term benefit found for PCT-guided antibiotic treatment in children

A groundbreaking UK study in The Lancet has examined whether an additional blood test called procalcitonin (PCT) could safely shorten the time children spend on intravenous (IV) antibiotics in hospitals.

15 Jan 2025

Experimental blood test for pancreatic cancer moves closer to real-world use

An experimental blood test for pancreatic cancer that was developed by Van Andel Institute and University of Pittsburgh scientists is being evaluated by a commercial laboratory, an important milestone toward making the test available for patients.

13 Jan 2025

Research identifies role of PV interneurons in pain processing

A research team led by Prof. HU Li at the Institute of Psychology of the Chinese Academy of Sciences, has revealed that parvalbumin (PV) interneurons in the primary somatosensory cortex (S1) preferentially encode pain intensity and drive nociceptive-evoked gamma oscillations (GBOs).

13 Jan 2025

Blood vessel dysfunction in brain's temporal lobes linked to mild cognitive impairment

Mild cognitive impairment is linked to blood vessel dysfunction in the brain's temporal lobes - the seat of memory - according to a new USC-led study.

13 Jan 2025

CeVD-related brain network phenotype can provide insights into cognitive decline trajectory

Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.

13 Jan 2025

New test could predict lung cancer outcomes using tumor DNA

Scientists from the Francis Crick Institute, UCL, UCLH and Personalis have found that a test to detect circulating tumor DNA can predict lung cancer outcome in a Cancer Research UK-funded study.

13 Jan 2025

Early diagnosis of Dementia with Lewy Bodies could be improved by cognitive profiling

Cognitive profiles for early diagnosis of Dementia with Lewy bodies (DLB) have been outlined in a new study, out today in Alzheimer's & Dementia.

10 Jan 2025

Machine learning reveals why cancer trials fall short in real-world patients

TrialTranslator uses machine learning to assess cancer RCT generalizability, revealing survival gaps for high-risk patients and enhancing research accuracy.

10 Jan 2025

RNAConnect Debuts The New UltraMarathonRT® RT-qPCR Kit to Improve Reliability Of Gene Expression Analysis

UltraMarathonRT® RT-qPCR Kit offers unmatched data reliability and sensitivity for gene expression studies, streamlining workflows and preserving RNA integrity.

From RNAConnect 10 Jan 2025

Hormonal changes after menopause impact multiple sclerosis severity

A new study by UC San Francisco has found that menopause revs up the progression of multiple sclerosis (MS).

10 Jan 2025

The X factor: Decoding brain aging differences between men and women

Researchers unveil how biological sex influences brain aging, revealing genetic, hormonal, and molecular mechanisms behind cognitive resilience and decline.

9 Jan 2025

World’s largest proteomics study launched by UK Biobank

UK Biobank has today announced the launch of the world's most comprehensive study of the proteins circulating in our bodies, which will transform the study of diseases and their treatments.

9 Jan 2025

Procalcitonin test fails to shorten antibiotic use in hospitalized children

A groundbreaking UK study led by the University of Liverpool has examined whether an additional blood test called procalcitonin (PCT) could safely shorten the time children spend on intravenous (IV) antibiotics in hospitals.

9 Jan 2025

Targeting miR-4274 and PEX5 can help overcome radioresistance in colorectal cancer

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge.

9 Jan 2025

New test predicts lung cancer survival better than current standards

Researchers at the Francis Crick Institute, the UCL Cancer Institute and UCLH have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors.

9 Jan 2025

Stanford researchers develop AI model to enhance cancer prognosis predictions

The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care.

8 Jan 2025