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Building Bridges to Scalable Allogeneic Cell Therapy

Rui Tostoes, Chief Technology Officer at ImmuneBridge, shares how his team is redefining preclinical development and large-scale manufacturing for allogeneic cell therapies.

From Hanson Wade Group - 7th Allogeneic Cell Therapies Summit 27 May 2025

Researchers find way to protect mitochondria from stress-induced damage

Mitochondria are the cell's power plants: They turn the food we eat into the energy our cells can use. But when stress hijacks the process they use to maintain their quality, they get snipped into useless fragments and go into a tailspin that spreads from cell to cell and triggers a wide range of human diseases.

26 May 2025

Novel immune cells identified as potential target for tuberculosis vaccines

There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern.

26 May 2025

Universal rules for designing optimal enzymes

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) now derived universal rules to enable the de novo design of optimal enzymes.

25 May 2025

Sartorius launches the Octet® R8e System: Real-time, label-free biomolecular interaction analysis with unprecedented sensitivity and efficiency

The life science group Sartorius launches the new Octet® R8e biolayer interferometry (BLI) system, providing researchers with its most advanced detection capabilities to date for real-time, high-throughput analysis of protein-protein, protein-small molecule, and other biomolecular interactions.

24 May 2025

Targeting astrocytes could boost immunotherapy effectiveness in glioblastoma

Our study investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against glioblastoma (GBM)-a highly aggressive brain cancer.

23 May 2025

Tufts researchers develop dental floss sensor for real time stress monitoring

Chronic stress can lead to increased blood pressure and cardiovascular disease, decreased immune function, depression, and anxiety.

23 May 2025

Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

23 May 2025

Waters acquires Halo Labs, expanding biological analysis portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

From Waters Corporation 23 May 2025

Cysteine depletion triggers rapid weight loss in mice

Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.

22 May 2025

Reducing Polypharmacy with Innovative Drug Formulation Technologies

Discover how hot melt extrusion supports polypharmacy reduction and novel therapies for stroke and snakebite with expert insights.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 22 May 2025

New CRISPR technology delivers RNA precisely to repair damaged brain cells

When a neuron in our body gets damaged, segments of RNA produce proteins that can help repair the injury.

21 May 2025

JAX study sheds light on infection vulnerability in patients with rare mitochondrial diseases

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions.

21 May 2025

How innovation in dried blood spot testing is transforming neurological disease monitoring

In this interview, NewsMedical speaks with Quanterix about blood spot testing for neurological applications.

From Quanterix 21 May 2025

New Alzheimer's drug candidate reduces toxic protein and improves memory in mice models

As researchers work to improve treatment of Alzheimer's disease, new research by UCLA Health identified a candidate drug that reduces levels of a toxic form of a protein in the brain caused by the disease and improved memory in mice by boosting production of a protective protein.

20 May 2025

New discovery may help explain why some people infected with CHIKV develop severe joint pain

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world. The virus typically causes flu-like symptoms, but it can also trigger chronic, severe joint pain in some people.

20 May 2025

Personalized gene editing corrects fatal infant metabolic disorder in world-first treatment

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening inborn error of metabolism. This pioneering approach chemically corrects the underlying mutation without cutting DNA, showing promise for precision treatment of ultrarare genetic disorders.

20 May 2025