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Researchers track how Osmium reacts in a single cancer cell

Osmium is a rare precious metal that could be used to treat cancer with fewer side effects when compared to Platinum, currently used in nearly half of chemotherapies.

17 Feb 2021

Novel polymer dots are a big step toward single-particle tissue imaging

A polymer that is custom designed to produce light that penetrates murky environments has shown promise in bioimaging trials, where it can detect nano-sized particles underneath the surface of realistic tissue models.

16 Feb 2021

Researchers create new cancer optotheranostics based on photosynthetic bacteria

Cancer is one of the most thought-provoking healthcare problems throughout the world. The development of therapeutic agents with highly selective anti-cancer activities is increasingly attractive due to the lack of tumor selectivity of conventional treatments.

16 Feb 2021

Using a smartphone-based microscope for detecting single molecules and diagnosing diseases

Biomarkers play a central role in the diagnosis of disease and assessment of its course. Among the markers now in use are genes, proteins, hormones, lipids and other classes of molecules.

13 Feb 2021

Study explores how membraneless organelles form and organize themselves

In cells, numerous important biochemical functions take place within spherical chambers made from proteins and RNA.

9 Feb 2021

Tiny nanoparticles furnished with dyes could be used for new imaging techniques

Tiny nanoparticles can be furnished with dyes and could be used for new imaging techniques, as chemists and physicists at Martin Luther University Halle-Wittenberg (MLU) show in a recent study.

9 Feb 2021

Researchers gain insight into the biological processes of chytrid fungus

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

8 Feb 2021

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

A team of scientists from France has recently designed fluorescence in situ hybridization probes (CoronaFISH) to visualize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in infected cells. A detailed description of the probe design, validation, and application is currently available on the bioRxiv preprint server.

7 Feb 2021

Researchers explore the origin of the body axis in animals

Egg cells start out as round blobs. After fertilization, they begin transforming into people, dogs, fish, or other animals by orienting head to tail, back to belly, and left to right.

5 Feb 2021

Assistant professor from University of Tennessee receives $1.9 million for retinal research

Thirumalini Vaithianathan, PhD, assistant professor in the Department of Pharmacology, Addiction Science, and Toxicology at the University of Tennessee Health Science Center, has spent a decade studying molecular signaling involved in vision. She has just received $1.9 million from the National Eye Institute for her project titled, "Dynamics of calcium signals control neurotransmitter release in retinal ribbon Synapses".

5 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Applications and Advantages of High-Speed AFM

AZoM talks to Professor Toshio Ando about his interest in high-speed AFM (HS-AFM) and how it can revolutionize observation of protein molecules.

From Bruker Nano Surfaces and Metrology 4 Feb 2021

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

Oxygen is essential for human life, but within the body, certain biological environmental conditions can transform oxygen into aggressively reactive molecules called reactive oxygen species (ROS), which can damage DNA, RNA, and proteins.

4 Feb 2021

Breast cancer‐on‐a‐chip to test the effectiveness of checkpoint inhibitor drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

2 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Study unravels relationship status of important receptor on immune and cancer cells

An important receptor on the surface of cancer and immune cells prefers to remain noncommittal; sometimes it is present as a single, sometimes as a pair. This was first shown by an MDC team in the journal PNAS, and will decisively advance the development of new medications.

30 Jan 2021

Scientists unravel how lipids distribute proteins within cells

An international team of scientists, coordinated by the Seville Institute of Biomedicine and the University of Seville has solved one of the hitherto unresolved enigmas of basic biology: how exactly do lipids distribute proteins within a cell? To do this, they used a new, completely innovative microscopy technology, which they applied to "mutant" cells they designed in their laboratory.

29 Jan 2021

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN.

27 Jan 2021

Pain-free microneedle patch can capture biomarkers from interstitial fluid

Blood draws are no fun. They hurt. Veins can burst, or even roll - like they're trying to avoid the needle too, Oftentimes, doctors use blood samples to check for biomarkers of disease: antibodies that signal a viral or bacterial infection, such as SARS-CoV-2, the virus responsible for COVID-19, or cytokines indicative of inflammation seen in conditions such as rheumatoid arthritis and sepsis.

26 Jan 2021

New NIH grant supports research on Alzheimer's disease caused by gene mutations

A new grant from the National Institute On Aging at the National Institutes of Health will support ongoing research at Rensselaer Polytechnic Institute to address Alzheimer's disease caused by gene mutations.

26 Jan 2021