Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

The Role of D-Amino Acids in Humans

In this interview, Dr. Daniel Armstrong from the University of Texas at Arlington talks to News-Medical Life Sciences about his upcoming Pittcon presentation.

From Pittcon 4 Mar 2021

New Nature Communications publication by Mann & Theis Groups harnesses the benefits of large-scale peptide collisional cross section (CCS) measurements and deep learning for 4D-proteomics

Bruker Corporation today announces a seminal publication from the groups of Professors Matthias Mann and Fabian Theis in the journal Nature Communications with the title ‘Deep learning the collisional cross sections of the peptide universe from a million experimental values’ by Florian Meier et al.

From Bruker Daltonics 4 Mar 2021

Analytical Mass Spectrometry: How Did We Get Here, Where are We Going?

News-Medical interviews Rick Yost, winner of the Pittsburgh Analytical Chemistry Award 2021, about his research into mass spectrometry.

From Pittcon 3 Mar 2021

Some types of fat are more resistant to weight loss, shows study

Scientists have mapped out what happens to fat deposits during intermittent fasting (every second day), with an unexpected discovery that some types of fat are more resistant to weight loss.

3 Mar 2021

Lung cancer cells activate different signaling pathways in response to KRAS inhibitors

Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options.

1 Mar 2021

Well-known spasmolytic drug can suppress inflammatory response in astrocytes

Biologists from RUDN University confirmed that a well-known spasmolytic drug called hymecromone can suppress the inflammatory response in astrocytes, important glial cells of the central nervous system.

26 Feb 2021

Full characterization of mammalian-produced SARS-CoV-2 receptor binding domains

A research paper recently uploaded to the preprint server bioRxiv by Dominguez-Vega et al. (23rd Feb, 2021) describes an in-depth structural analysis of the RBD of the spike protein expressed in mammalian Chinese hamster ovary (CHO) cells and human embryonic kidney (HEK293) cells, providing a new understanding of protein structure and function.

24 Feb 2021

Researchers uncover 'hotspots' on the Spike protein that are critical for SARS-CoV-2 infection

The COVID-19 pandemic has prompted considerable investigation into how the SARS-CoV-2 Spike protein attaches to a human cell during the infection process, as this knowledge is useful in designing vaccines and therapeutics.

22 Feb 2021

Children exposed to air pollution may be at higher risk of disease in adulthood

Children exposed to air pollution, such as wildfire smoke and car exhaust, for as little as one day may be doomed to higher rates of heart disease and other ailments in adulthood, according to a new Stanford-led study.

22 Feb 2021

Study provides new information about the structure of prion proteins

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

20 Feb 2021

Novel gel electrophoresis method for MS-based quantification of protein biomarkers

Mass spectrometry (MS) is a powerful method for biomarker analysis because it enables highly sensitive and accurate measurement of target molecules in clinical samples.

18 Feb 2021

Researchers track how Osmium reacts in a single cancer cell

Osmium is a rare precious metal that could be used to treat cancer with fewer side effects when compared to Platinum, currently used in nearly half of chemotherapies.

17 Feb 2021

Top scientists, advances in analytical chemistry recognized

Each year, Pittcon provides a venue where scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy are honored.

From Pittcon 16 Feb 2021

Innovations in Forensic Examination of Seized Drugs and Forensic Toxicology

NewsMed interviews Michelle Peace on her Pittcon presentation entitled, "Innovations in Forensic Examination of Seized Drugs and Forensic Toxicology".

From Pittcon 15 Feb 2021

The Future of Environmental and Food Monitoring

NewsMed interviews Professor Antje Baeumner about the future of food and environmental monitoring, the subject of her 2021 Pittcon presentation.

From Pittcon 12 Feb 2021

Study investigates multi-enzyme complex that plays key role in metabolism

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists at Martin Luther University Halle-Wittenberg (MLU) and TU Berlin have published their findings in the journal Cell Reports.

11 Feb 2021

Metabolomics and machine learning used to identify possible COVID-19 biomarkers

One of the many mysteries still surrounding COVID-19 is why some people experience only mild, flu-like symptoms, whereas others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage.

10 Feb 2021

Taking Advantage of Measuring Molecular Collisional Cross-Sections in Pharma

News-Medical talks to Mike Greig, Director of Pharma at Bruker, about why measuring collisional cross-sections is beneficial to developing new drugs.

From Bruker Daltonics 10 Feb 2021

Study finds way to detect ovarian cancer in patients using Pap test samples

A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer.

9 Feb 2021