Efficacy News and Research

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Study finds differences in side-effects experienced by male and female OG cancer patients

Men and women may need to be treated differently - at least when it comes to some types of cancer. In an analysis to be presented at the ESMO 2018 Congress in Munich, data was pooled from four UK randomized controlled clinical trials of first line chemotherapy in oesophagogastric cancer, finding significant differences in a number of important side-effects experienced by male and female patients.

19 Oct 2018

High rate of non-adherence to hormonal therapy found among premenopausal early breast cancer patients

Nearly one in six premenopausal women being treated for early stage breast cancer do not adhere adequately to tamoxifen therapy after one year of treatment, potentially putting themselves at increased risk of recurrence and reduced survival, a French prospective study reports at ESMO 2018.

19 Oct 2018

Experts warn about use of cardboard baby cribs

There has been a recent trend of cardboard baby boxes for infants that are supposed to promote their sleeping. Some have claimed these boxes to be safer than traditional cots, cradles and bassinets.

19 Oct 2018

Genetically modifying zebrafish provides numerous, highly accurate disease models

Research published today describes how zebrafish can be genetically engineered to produce more accurate models of human disease.

18 Oct 2018

Self-lubricating condoms may help raise condom usage

Researchers have come up with self lubricating condoms that become slippery or lubricated once they come in contact with skin. This would not only raise the pleasure factor of condom usage they feel, but in turn also raise usage of condoms and reduce the incidence of sexually transmitted diseases (STDs) and unwanted pregnancies.

18 Oct 2018

UC researcher focuses on light-mediated therapies to target breast cancer

When treatment is working for a patient who is fighting cancer, the light at the end of the tunnel is easier to see.

17 Oct 2018

Mice study shows antibiotics are not always necessary to cure sepsis

Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice.

17 Oct 2018

New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

HealthCore, Inc., the outcomes research subsidiary of Anthem, Inc. and Novo Nordisk Inc., which manufacturers the once weekly GLP-1 receptor agonist Ozempic (semaglutide), are working together to launch the first of its kind pragmatic study to understand the benefits of semaglutide as compared with all other available diabetes drugs in a real-world pragmatic clinical trial for Type 2 diabetes - one of the nation's fastest growing chronic diseases.

17 Oct 2018

Using Galleria mellonella to assess acute toxicity of chemicals

TruLarv is considered a non-animal technology in the context of UK animal use regulations where procedures on this species are not regulated.

17 Oct 2018

Purdue Pharma, Eisai announce positive topline results from Phase 3 study of lemborexant

Eisai Co., Ltd. and Purdue Pharma L.P. announced positive topline results from SUNRISE 2, a long-term Phase 3 efficacy and safety evaluation of lemborexant, an investigational agent for sleep-wake regulation currently being studied for the potential treatment of multiple sleep-wake disorders.

17 Oct 2018

Researchers awarded grant to advance testing of experimental heroin vaccine

Researchers at the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research and SUNY Upstate Medical University in Syracuse, N.Y., have been awarded a grant to advance an experimental heroin vaccine through Phase I/IIa clinical trials to assess both its safety and its efficacy against a morphine challenge.

17 Oct 2018

Purdue researchers develop new chemical process to find better drug 'fits' for patients

When a medication doesn't "fit" the body quite right, the results can be devastating. Such is the case for thalidomide, which was prescribed in the 1950s and 1960s as a sedative or hypnotic, even for pregnant women.

16 Oct 2018

New family planning app found to be as effective as modern methods

Early results from a first-of-its-kind study suggests that typical use of a family planning app called Dot is as effective as other modern methods for avoiding an unplanned pregnancy.

16 Oct 2018

Allele awarded NIH grant to develop nanoantibody therapies for treatment of sepsis

The National Institute of General Medical Sciences of NIH has awarded a Small Business Innovative Research grant to Allele Biotechnology and Pharmaceuticals to develop new single-domain nanoantibody therapies for the treatment of sepsis.

15 Oct 2018

Abnormal vision in childhood can affect development of brain areas responsible for attention

A research team has discovered that abnormal vision in childhood can affect the development of higher-level brain areas responsible for things such as attention.

15 Oct 2018

Researchers to study the use of CRISPR on human liver on-a-chip platform

Two Arizona State University professors are among the first recipients of Somatic Cell Genome Editing grants from the National Institutes of Health Common Fund. The $2,600,000, five-year grant will fund the first study of the genome editing technology CRISPR to be used on a "human liver on-a-chip" platform.

15 Oct 2018

Hidden drugs and danger lurk in over-the-counter supplements, study finds

Everyone has seen the ads or the products on the shelves. A dietary supplement that promises to make consumers skinny, without dieting or exercise. Or the one that will bulk them up and turn them into the envy of other weightlifters at the gym. Not to mention the one to make them perform better in the bedroom.

12 Oct 2018

KNAUER high-pressure dosing pumps contribute to the success of Grillo’s new MSA synthesis

The Berlin-based manufacturer of laboratory measuring instruments KNAUER Wissenschaftliche Geräte GmbH reported today, that its high-pressure metering pumps played an important role in the development of the groundbreaking new manufacturing process of methanesulfonic acid directly from methane and sulfur trioxide, which was successfully realized by researchers from Duisburg's Grillo-Werke AG.

From KNAUER Wissenschaftliche Geräte GmbH 12 Oct 2018

Video games could influence bystander attitudes and efficacy in situations of sexual assaults

As recent news headlines have shown, bystanders can play a pivotal role when it comes to sexual assault and relationship violence.

12 Oct 2018

A new vaccine shows promise in protecting people from rabies, Lassa fever

A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications.

12 Oct 2018

Efficacy News and Research

Study finds differences in side-effects experienced by male and female OG cancer patients

High rate of non-adherence to hormonal therapy found among premenopausal early breast cancer patients

Experts warn about use of cardboard baby cribs

Genetically modifying zebrafish provides numerous, highly accurate disease models

Self-lubricating condoms may help raise condom usage

UC researcher focuses on light-mediated therapies to target breast cancer

Mice study shows antibiotics are not always necessary to cure sepsis

New pragmatic study launched to understand the effectiveness of new type 2 diabetes drug

Using Galleria mellonella to assess acute toxicity of chemicals

Purdue Pharma, Eisai announce positive topline results from Phase 3 study of lemborexant

Researchers awarded grant to advance testing of experimental heroin vaccine

Purdue researchers develop new chemical process to find better drug 'fits' for patients

New family planning app found to be as effective as modern methods

Allele awarded NIH grant to develop nanoantibody therapies for treatment of sepsis

Abnormal vision in childhood can affect development of brain areas responsible for attention

Researchers to study the use of CRISPR on human liver on-a-chip platform

Hidden drugs and danger lurk in over-the-counter supplements, study finds

KNAUER high-pressure dosing pumps contribute to the success of Grillo’s new MSA synthesis

Video games could influence bystander attitudes and efficacy in situations of sexual assaults

A new vaccine shows promise in protecting people from rabies, Lassa fever

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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