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Deep brain stimulation rewires brain circuits linked to depression

Researchers from the Icahn School of Medicine at Mount Sinai have uncovered the first direct evidence that deep brain stimulation (DBS) can remodel white matter pathways in the brain and alter communication across large-scale neural networks, revealing a previously unrecognized mechanism that may explain how the therapy helps patients recover from severe depression.

1 Jun 2026

Pediatric experts reveal the 10 research areas set to shape child health

Pediatric research leaders identified 10 high-promise areas likely to shape child health over the next 5 to 10 years, including genomics, mental health, vaccines, artificial intelligence, perinatal medicine, precision therapeutics, health equity, nutrition, environmental health, and cancer treatment. The paper argues that these opportunities will only translate into better outcomes if pediatric research receives sustained funding, public trust, workforce support, advocacy, and equitable implementation.

1 Jun 2026

Brazilian study links TP53 mutations to poor lung cancer prognosis

Lung cancer is the most common and deadly form of cancer worldwide. It is increasingly understood to be a complex genetic disease with different mutations that vary according to factors such as smoking and ethnicity.

1 Jun 2026

Mature intestinal cells regain stem cell behavior to trigger tumor growth

In a groundbreaking study, Stevens researchers show how colorectal cancers can evolve from mature intestinal cells that revert to stem cells.

1 Jun 2026

Physical activity protects heart health regardless of weight loss

With obesity now affecting more than 40% of U.S. adults and fueling rising rates of heart disease, a new scientific statement from the American Heart Association calls for a comprehensive treatment approach that puts physical activity front and center.

1 Jun 2026

Weight loss drugs could widen health inequalities without nutritional support

Drugs such as semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro) are transforming obesity treatment, but without affordable, healthy food and appropriate support, they could widen health inequalities in the UK, according to researchers at UCL and the University of Cambridge.

1 Jun 2026

Health workers face hidden exposure to cancer-linked hazards

A study reveals high exposure to cancer risk factors among health and social care workers in Europe, underscoring the need for enhanced protective measures.

1 Jun 2026

Lower Alzheimer’s amyloid levels in Black and Latinx adults

Findings show lower amyloid PET positivity in Black and Latinx adults with cognitive impairment, highlighting disparities in dementia diagnosis and treatment.

1 Jun 2026

Global policy gaps slow biosimilar adoption and access

Nine out of 10 prescriptions are filled by generic drugs - FDA-approved carbon copies of brand-name drugs with expired patents.

1 Jun 2026

Online resources on AI and cancer lack quality, need improvement

Online information about artificial intelligence (AI) and its impact on cancer research and treatment for both the patient and general-public audiences is limited, and the available webpages and videos are largely of low quality, difficult to read, and frequently omit risks of AI use, according to new research presented today at the at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting (Abstract 9000) and led by researchers from the Abramson Cancer Center (ACC) of the University of Pennsylvania and Penn's Perelman School of Medicine.

1 Jun 2026

High-risk prostate cancer patients benefit from perioperative apalutamide therapy

High-risk localized and locally advanced prostate cancer patients treated with apalutamide - a next generation neoadjuvant androgen-receptor pathway inhibitor (ARPI) - plus hormone therapy before and after prostate cancer surgery resulted in more major pathologic responses and reduced the risk of metastasis or death, meeting both primary endpoints, in an international phase 3 clinical trial led by principal investigator Mary-Ellen Taplin, MD, medical oncologist at Dana-Farber Cancer Institute, and Adam Kibel, MD, chair of the Department of Urology at Mass General Brigham.

31 May 2026

Daraxonrasib significantly extends survival in metastatic pancreatic cancer

At the ASCO annual meeting, Dana-Farber's Brian Wolpin, MD, MPH, will present positive results from the RASolute 302 trial showing a substantial prolongation of survival for patients with previously treated metastatic pancreatic cancer, regardless of RAS mutation status, taking daraxonrasib, an investigational oral RAS(ON) multi-selective inhibitor, compared with chemotherapy.

31 May 2026

Denzel Ward encourages lifesaving Hands-Only CPR action across Cleveland

Cleveland Browns cornerback and American Heart Association Nation of Lifesavers™ NFL Player Ambassador Denzel Ward is taking his impact beyond the field and into the heart of the city appearing on new billboards across Cleveland for National CPR and AED Week, June 1-7 annually.

29 May 2026

Researchers uncover new clues about the origin of Alzheimer's tau tangles

Researchers at Columbia University have uncovered new clues about the earliest molecular events that may trigger Alzheimer's disease, shedding light on how toxic tau filaments begin to form in the brain.

29 May 2026

Gene test helps many breast cancer patients avoid chemotherapy

Many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning, a large international clinical trial led by UCL has found.

29 May 2026

Physician groups welcome landmark overhaul of federal dispute process

The American Society of Anesthesiologists (ASA), American College of Emergency Physicians (ACEP) and American College of Radiology (ACR) today applauded the final Independent Dispute Resolution (IDR) Operations Rule under the No Surprises Act (NSA) released on May 28, commending federal agencies for their thoughtful and collaborative approach in addressing longstanding challenges and advancing a more functional, transparent dispute resolution system.

29 May 2026

Free contraception program sharply reduces patient spending in British Columbia

Researchers at UBC found that B.C.'s decision to provide universal, no-cost prescription contraception sharply reduced what patients pay, with the largest financial gains for people in their 20s.

29 May 2026

New protocol screens clinical research participants for prior radiation exposure

A new study highlights a critical gap: most clinical research studies that use imaging techniques such as amyloid positron emission tomography (PET) scans do not account for the radiation participants have already received from prior medical procedures.

29 May 2026

Researchers develop open source framework for health AI research

A research team led by Columbia University has developed an open-source framework designed to streamline and accelerate artificial intelligence research using health data, addressing longstanding challenges in data standardization, reproducibility, and collaboration across institutions.

29 May 2026

Unhealthy snacks drive disruptive behavior in young children

Researchers at the University of Agder (UiA) have already identified clear links between what children eat and their mental health as early as the age of four.

29 May 2026