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American Gene Technologies receives second immuno-oncology patent

American Gene Technologies International Inc., a leading gene and cell therapy company, today announced receipt of a second immuno-oncology patent on the stimulation of gamma delta T cells for treating solid tumors in epithelial cancers.

20 Mar 2018

Northwestern scientists bring precision medicine to rheumatoid arthritis

Scientists are bringing precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new Northwestern Medicine multi-site study.

19 Mar 2018

Male birth control pill taken once a day shows success

A new birth control pill for men with a hormonal component has shown efficacy and safety in preventing pregnancies when used once daily for a month. The study was presented yesterday (18th of March 2018) at the ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Illinois.

19 Mar 2018

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Once funding is obtained, researchers can perform a clinical trial to test the efficacy of transplanting bone marrow cells into muscles to stop deterioration caused by the illness. The method has already yielded positive results on mice.

16 Mar 2018

Study questions efficacy, safety of intranasal ketamine for depression

Nasal spray devices have been touted as a promising way to deliver ketamine to patients with treatment-resistant depression, with this application easier to use and less invasive than other clinical delivery methods such as injections.

16 Mar 2018

Study finds limited data to support effectiveness of digital rectal exam in primary care

Although the digital rectal exam is widely used in primary care to screen for prostate cancer, a new study finds limited data to support its effectiveness.

14 Mar 2018

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Biofilms are surface-attached communities of bacterial or fungal cells that are enmeshed in an extensive extracellular matrix which makes them more resistant to both antibiotics and the immune system.

13 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

Gastrointestinal hormone offers possible new treatment for NAFLD and NASH patients

Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Exercise may reduce potential effectiveness of heart drug

Peter Ruben and his team of researchers have spent years studying why seemingly healthy patients with inherited cardiac arrhythmias can sometimes suddenly die during exercise.

8 Mar 2018

Childhood maltreatment has moderating influence on efficacy of psychotherapy

In the current issue of Psychotherapy and Psychosomatics, Klein and colleagues report the effect of childhood maltreatment on the outcome of psychotherapy.

7 Mar 2018

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

An international research team led by the Institute of Bioengineering and Nanotechnology of the Agency for Science, Technology and Research and IBM Research developed a synthetic molecule that can kill five deadly types of multidrug-resistant bacteria with limited, if any, side effects.

7 Mar 2018

FDA approves new antiretroviral medication for patients with multidrug-resistant HIV

Today, the U.S. Food and Drug Administration approved Trogarzo (ibalizumab-uiyk), a new type of antiretroviral medication for adult patients living with HIV who have tried multiple HIV medications in the past (heavily treatment-experienced) and whose HIV infections cannot be successfully treated with other currently available therapies (multidrug resistant HIV, or MDR HIV).

6 Mar 2018

Text messaging may hold promise in helping ALD liver-transplant patients maintain sobriety

Each year in the U.S., more than 40,000 patients need a liver transplant because of complications associated with cirrhosis and liver failure. Alcohol-related liver disease (ALD) alone accounts for nearly 30 percent of all liver transplants, yet up to 50 percent of patients with alcoholism return to drinking within five years of undergoing a liver transplant.

5 Mar 2018

Antibiotic use may affect efficacy of cancer immunotherapies

Antibiotic use is known to have a near-immediate impact on our gut microbiota and long-term use may leave us drug-resistant and vulnerable to infection.

2 Mar 2018

CRISPR-like gene editing could be potential way to treat patients with harmful blood lipid levels

Using a variation of CRISPR gene editing may be a potential strategy for mimicking the protective effects of a genetic mutation linked to lower cholesterol levels and heart disease risks, according to new mouse research from the Perelman School of Medicine at the University of Pennsylvania published this week in Circulation.

28 Feb 2018

Failed osteoarthritis drug may help lessen opioid dependence

A new study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used in combination with opioid-based pain medications.

27 Feb 2018

New proactive app could connect breastfeeding mothers with lactation consultants

A newly developed proactive app could instantly connect breastfeeding mothers with pediatricians or lactation consultants to help collect data, monitor patients and provide consultation and support while improving breastfeeding outcomes for new mothers.

27 Feb 2018

New treatment shows promise to fight against serious inflammatory disease

Still's disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen. It is caused by a deregulation of the immune system triggering an acute inflammatory response.

27 Feb 2018

Efficacy News and Research

American Gene Technologies receives second immuno-oncology patent

Northwestern scientists bring precision medicine to rheumatoid arthritis

Male birth control pill taken once a day shows success

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Study questions efficacy, safety of intranasal ketamine for depression

Study finds limited data to support effectiveness of digital rectal exam in primary care

Study uses ACEA Biosciences’ xCELLigence assay to monitor disruption of S. aureus biofilms

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

Gastrointestinal hormone offers possible new treatment for NAFLD and NASH patients

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Exercise may reduce potential effectiveness of heart drug

Childhood maltreatment has moderating influence on efficacy of psychotherapy

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

FDA approves new antiretroviral medication for patients with multidrug-resistant HIV

Text messaging may hold promise in helping ALD liver-transplant patients maintain sobriety

Antibiotic use may affect efficacy of cancer immunotherapies

CRISPR-like gene editing could be potential way to treat patients with harmful blood lipid levels

Failed osteoarthritis drug may help lessen opioid dependence

New proactive app could connect breastfeeding mothers with lactation consultants

New treatment shows promise to fight against serious inflammatory disease

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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