Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Rozanolixizumab prevents congenital heart block in high-risk pregnancy

Congenital heart block, sometimes referred to as cardiac neonatal lupus, is a rare but potentially life-threatening condition that affects babies born to mothers with specific autoantibodies - called anti-SSA/Ro antibodies - which can attack the fetal heart via its electrical conduction system, leading to a slower heart rate.

22 Oct 2025

Epigenetic editing enables safer and more effective T cell therapies

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary human T cells, addressing a key manufacturing and scalability challenge in next-generation cell therapies.

21 Oct 2025

Researchers link postmenopausal status to increased dry eye risk

Many symptoms, such as hot flashes and vaginal dryness, are commonly associated with the menopause transition. One of the lesser-known symptoms that worsens in midlife is dry eyes. A new study suggests that postmenopausal women exhibit a higher prevalence of dry eye disease than perimenopausal women.

21 Oct 2025

Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment

Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the cells that produce insulin-a critical hormone that regulates blood sugar in the body.

8 Oct 2025

New drug candidates show promise for restoring myelin in MS

Multiple sclerosis, or MS, is a chronic autoimmune disease affecting more than 2.9 million people worldwide.

8 Oct 2025

X-HiDE project advances toward earlier detection and precision treatment of inflammatory diseases

Facilitating earlier diagnosis and more precise treatment for patients with inflammatory diseases. This is the goal as the X-HiDE research project at örebro University in Sweden now enters its next phase, in collaboration with eleven companies and four other universities in Europe and the USA.

8 Oct 2025

Stem cells and organoids offer a new understanding of APOL1 kidney disease

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for CKD include mutations in a gene called APOL1.

3 Oct 2025

New study reveals silent onset of rheumatoid arthritis

Scientists have discovered that rheumatoid arthritis (RA) doesn't start when the pain begins. It silently starts years earlier.

24 Sep 2025

New findings support low-dose ATG to delay progression of type 1 diabetes

New research presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) and published simultaneously in The Lancet shows that a much lower dose than previously thought of the old immunomodulatory drug anti-thymocyte globulin (ATG) is safe and effective in preventing progression of type 1 diabetes (T1D) in young people.

19 Sep 2025

Verapamil shows potential for preserving beta-cell function in type 1 diabetes

New research (the Ver-A-T1D trial) presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Vienna, 15-19 September) shows that slow-release (SR) verapamil (360mg daily) could have a potential effect on beta-cell function in adults with newly diagnosed type 1 diabetes.

18 Sep 2025

Novel method accurately identifies therapeutic antibodies to treat infectious diseases

Scientists at Scripps Research have developed a novel method that uses artificial intelligence (AI) and advanced imaging techniques to more accurately and efficiently identify therapeutic antibodies to treat infectious diseases.

10 Sep 2025

Targeting ADAR1 offers new hope against glioblastoma

The most common and aggressive type of adult brain cancer, glioblastoma multiforme (GBM) is notoriously resistant to treatment, with a median survival of just 14 months following diagnosis.

5 Sep 2025

First FDA-approved islet transplant at UI Health ends insulin dependence

Doctors at UI Health performed the first islet transplant with Lantidra, the only therapy approved by the U.S. Food and Drug Administration to treat brittle type 1 diabetes.

4 Sep 2025

Penn State researchers reveal new function of antibody-producing cells

The body has an intricate system to defend against infections where each type of immune cell plays a distinct role. Now, a study led by researchers from the Penn State College of Medicine has uncovered a new function of the immune cells that are known for making antibodies.

3 Sep 2025

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

A nationwide Korean cohort study found that antibiotic use during pregnancy or early infancy did not increase overall risk of childhood autoimmune diseases. Subgroup signals for Crohn’s disease and autoimmune thyroiditis warrant cautious follow-up.

25 Aug 2025

New core dataset advances standardized care and research in systemic lupus erythematosus

The European Alliance of Associations for Rheumatology - has published new recommendations on core datasets to be used in systemic lupus erythematosus (SLE).

22 Aug 2025

New nanoparticle drug delivery system targets the spleen for precise lupus treatment

With a $1 million Impact Award from the U.S. Department of Defense, Tianfu Wu, a University of Houston biomedical engineer, is developing a method to send medication directly to the spleen where certain immune cells cause the disease known as lupus, or Systemic Lupus Erythematosus.

18 Aug 2025