Cardiometabolic News and Research

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Mount Sinai opens integrated clinical center for womens health

The Mount Sinai Health System is opening the Carolyn Rowan Center for Women's Health and Wellness, a transformative new model for women's health that brings together multidisciplinary clinical expertise, structured care pathways, and leading-edge research innovation to deliver more personalized, comprehensive care for women across the entire lifespan.

27 May 2026

Poor lipid metabolism may reduce cognitive performance in teens

A new Finnish study shows that blood markers of dysfunctional lipid metabolism are associated with poorer cognitive function in 15-17-year-olds.

27 May 2026

Retatrutide reshapes metabolism in obesity and type 2 diabetes, study finds

Retatrutide altered circulating metabolites and lipids linked to fatty acid oxidation and insulin resistance in people with obesity, with or without type 2 diabetes. These biomarker changes suggest improved metabolic health, but the post-hoc analysis remains hypothesis-generating and does not prove direct clinical benefit.

26 May 2026

Hydroxychloroquine lowers heart risks in skin lupus patients

A study led by investigators from Johns Hopkins Medicine found that some patients with discoid lupus erythematosus - a form of skin lupus commonly diagnosed in young to middle-aged Black women that causes disc-shaped plaques to form on the body - were less likely to experience complications, such as diabetes, hypertension and coronary artery disease if they were prescribed hydroxychloroquine.

26 May 2026

Indian adapted Mediterranean diet targets inflammation in heart disease trial

The paper describes a single-center randomized controlled trial testing whether an Indian Adapted Mediterranean Diet can reduce dietary inflammation in adults with stable coronary artery disease or moderate-to-high cardiovascular risk. The protocol will assess changes in the Dietary Inflammatory Index, inflammatory biomarkers, cardiometabolic risk factors, body measurements, and metabolic hormones over six months.

25 May 2026

Yoga and meditation show promise for gut health

This systematic review found that yoga and Buddhist meditation were associated with favorable gut microbiota and metabolite profiles in four human studies involving healthy adults. However, because participants largely followed vegetarian or vegan diets and no randomized controlled trials were included, the findings cannot prove that meditation alone reshapes the gut microbiome.

24 May 2026

New clinical guidelines outline strategies to improve postpartum cardiovascular care

A new Expert Consensus Decision Pathway by the American College of Cardiology (ACC) provides recommended strategies for improving postpartum care for individuals with and at risk for short- and long-term cardiovascular disease (CVD).

22 May 2026

Women may face greater cognitive impact from dementia risk factors

Researchers from the University of California San Diego School of Medicine found that women not only experience a higher burden of certain modifiable dementia risk factors, but also appear more vulnerable to their effects on cognitive function.

20 May 2026

Nutrition education improves diet quality in university students

Nutrition education at universities shows promise in improving dietary habits and mental well-being, highlighting the importance of healthy eating for students.

19 May 2026

Pregnancy-related disorders may shape offspring heart health into adulthood

Hypertensive disorders in pregnancy may lead to lasting cardiovascular issues in offspring, highlighting the need for improved maternal health strategies.

19 May 2026

Integrated care needed for lifelong Polyendocrine Ovarian Syndrome management

Polycystic Ovary Syndrome, which has just been renamed Polyendocrine Ovarian Syndrome (PMOS), is the most common hormonal and metabolic disorder affecting women of reproductive age, impacting up to 13% of this population and contributing to nearly 40% of infertility cases worldwide.

18 May 2026

Perimenopause nearly doubles women’s odds of poor heart health

Perimenopause is linked to worsening cardiovascular health, with significant declines in lipid and glucose scores, emphasizing the need for early assessment.

15 May 2026

Healthy plant-based foods may improve pregnancy cardiometabolic markers

Higher-quality plant-based diets were associated with more favorable cardiometabolic biomarkers in pregnant U.S. women, especially higher HDL-C and lower TG/HDL-C ratio. Indices that emphasized healthy plant foods, rather than simply penalizing animal foods, showed the strongest links with insulin resistance and lipid markers.

15 May 2026

Semaglutide significantly reduces obesity in treatment-resistant young adults

A weekly dose of semaglutide (2.4 mg) leads to a clinically significant reduction in body mass index (BMI) and related health outcomes in young adults with severe obesity who are treatment resistant following hospital-based non-pharmacological obesity care during childhood, according to a randomized controlled trial being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May).

13 May 2026

Why experts say PCOS needs a new name

A Lancet Health Policy paper reports an international consensus process that selected polyendocrine metabolic ovarian syndrome (PMOS) as the new name for polycystic ovary syndrome (PCOS). The change aims to shift the focus away from ovarian cysts and better reflect the condition’s endocrine, metabolic, and ovarian features.

13 May 2026

Once-daily orforglipron helps preserve weight loss after semaglutide or tirzepatide

Oral orforglipron helped adults maintain clinically meaningful weight loss after prior injectable tirzepatide or semaglutide therapy. The phase 3b ATTAIN-MAINTAIN trial suggests switching to once-daily oral therapy may help reduce weight regain when injectable treatment is discontinued.

13 May 2026

FoMO and anxiety may increase addictive eating risk

Research shows FoMO influences addictive eating, with anxiety heightening reward-driven cravings for ultra-processed foods and compulsive overeating.

12 May 2026

Two leading heart risk tools pass a major global test

A multinational Nature Medicine validation study found that PREVENT and SCORE2 cardiovascular risk equations performed generally well across 6.4 million people from observational cohorts and randomized trials. The findings support broader use of these tools for CVD risk stratification, while highlighting the need for local calibration and more validation in underrepresented regions.

11 May 2026

Urges for cardiologists to screen patients for UPF intake

The European Society of Cardiology identifies ultra-processed foods as a key cardiovascular risk, urging a shift in dietary guidelines for better heart health.

11 May 2026

Semaglutide shows sustained weight loss benefits in older adults

A new analysis of the STEP trails carried out by semaglutide manufacturer Novo Nordisk has analysed various trials to show the safety and efficacy of the obesity drug semaglutide in older adults (over 65 years), and found similar efficacy and safety as in the general trial populations .

11 May 2026