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TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

The Cancer Prevention and Research Institute of Texas (CPRIT) recently awarded grants to four researchers from the Texas Tech University Health Sciences Center (TTUHSC).

12 Oct 2023

Accelerating drug discovery with analytical R&D solutions

In this interview, Thermo Fisher Scientific discusses how to accelerate drug discovery through analytical R&D.

From Thermo Fisher Scientific – Materials & Structural Analysis 12 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Researchers utilize 3D printing to craft cerebral cortex tissues with organized neurons, offering potential treatments for brain injuries. This novel technique prints neural progenitors in layer-by-layer sequences, aiming for accurate tissue restoration in damaged brains.

8 Oct 2023

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Researchers reported that the increased long-term risk of acute cardiovascular complications associated with COVID-19 is linked to SARS-CoV-2 infecting coronary vessels and inducing the formation of plaques.

3 Oct 2023

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Researchers developed a point-of-care assay for the rapid detection of mpox virus.

20 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

Researchers discover backup protein quality control mechanism

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

14 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Kidney stones (KS), hard crystalline formations that occur within the kidney, are a common condition that affects millions of people worldwide.

11 Sep 2023

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

Elevated pressure in the bile canaliculi alters structure of the liver tissue

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called hepatocytes.

7 Sep 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023

Smartphone-based imaging reveals a breakthrough in identifying infected wounds

A recent study in "Frontiers in Medicine" evaluates the use of hyperspectral imaging (HSI) through a smartphone-based device to differentiate between infected and non-infected wounds. The study found that this portable approach offered 74% accuracy in wound assessment, including 100% sensitivity and 91% specificity in detecting infected wounds.

28 Aug 2023

New smartphone-based device can quickly identify infected wounds

It’s notoriously difficult for doctors to identify a wound that is becoming infected. Clinical signs and symptoms are imprecise and methods of identifying bacteria can be time-consuming and inaccessible, so a diagnosis can be subjective and dependent on clinician experience.

25 Aug 2023

Lung cells can be trained to counteract inflammation

Inflammation is a standard part of our bodies' immune system response. But sometimes this response becomes hyperactivated in our lungs, causing inflammation to continue unchecked, which can be fatal. Many deaths from COVID-19 have been due to excessive inflammation, which results in acute lung injury.

24 Aug 2023

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Researchers described the preclinical profile of JT002, a novel and orally bioavailable small molecule inhibitor of the NLRP3 inflammasome.

24 Aug 2023

Novel approach uses machine learning for quick and easy rheumatic disease diagnosis

Researchers evaluated fluorescence optical imaging as a method to accurately and rapidly diagnose rheumatic diseases of the hands.

24 Aug 2023

Fluorescence News and Research

TTUHSC receives nearly $2.3 million in CPRIT grants to support cancer research

Accelerating drug discovery with analytical R&D solutions

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers discover backup protein quality control mechanism

Reviving reservoirs: new findings shake up HIV treatment understanding

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

Elevated pressure in the bile canaliculi alters structure of the liver tissue

Light-driven bacteria could be used to target and kill cancer cells

Smartphone-based imaging reveals a breakthrough in identifying infected wounds

New smartphone-based device can quickly identify infected wounds

Lung cells can be trained to counteract inflammation

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

Novel approach uses machine learning for quick and easy rheumatic disease diagnosis

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