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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Study sheds light on the metabolism of Leishmania parasite

University of York scientists are part of an international team which has discovered how a parasite responsible for spreading a serious tropical disease protects itself from starvation once inside its human host.

17 Sep 2019

Scientists identify molecule that plays key role in determining fate of cells under stress

St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.

12 Sep 2019

Fat-filled immune cells found in victims of vaping illness

The frightening outbreak of mysterious respiratory illness linked to the use of e-cigarettes, or vaping, have shaken the medical community.

9 Sep 2019

Vaping-related respiratory illness characterized by lipid-laden macrophages in the lungs

Doctors have identified a previously unrecognized characteristic of the vaping-related respiratory illness that has been emerging in clusters across the U.S. in recent months.

8 Sep 2019

Vapor from e-cigarettes may impair the cells that line the lungs

Inhaling the vapor from e-cigarettes may cause cellular changes in the lungs that increase susceptibility to viruses, find scientists.

6 Sep 2019

Study reveals insights into new populations of immune cells in the lungs

Due to their function, the lungs are constantly exposed to various compounds carried in the air, sometimes harmful, sometimes harmless.

4 Sep 2019

Study gives insight into how immunotherapies may be delivered directly to brain tumors

A new study gives insight into how immunotherapies, treatments that help the body's immune system fight cancer, might one day be delivered directly to the brain in order to treat brain tumors.

29 Aug 2019

Scientists identify PoEMs that promote breast cancer metastasis

When breast cancer cells spread through the body, they do so mainly through the lymph system that normally removes excess fluid and waste products from our tissues.

28 Aug 2019

Novel immunotherapy method could overcome tumor immunity

Cancer immunotherapy is a form of treatment in which the body’s own immune cells are recruited to overcome the tumor. However, it is only useful in a few tumors, because of tumor immunity where tumor-associated immune cells work to protect the tumor against attack.

28 Aug 2019

Researchers find diverse immune cell profiles, roles in breast cancer resistance to immunotherapy

In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy.

27 Aug 2019

Removing tumor's protective wall could help boost the effects of cancer treatments

Scientists may have found a way to pull down the protective wall that surrounds tumors, potentially re-exposing them to the killing power of the immune system and immunotherapy treatments, according to a study part funded by Cancer Research UK and published in EBioMedicine today (Monday).

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Years ago, this doctor linked a mysterious lung disease to vaping

Dr. John E. Parker was working at a West Virginia hospital in 2015 when a 31-year-old female patient was admitted with acute respiratory problems.

23 Aug 2019

UC San Diego researchers identify new therapeutic approach to kill cancer cells

Epithelial cancers, such as cancers of the lung and pancreas, use the ανβ3 molecule to gain drug resistance to standard cancer therapies and to become highly metastatic.

22 Aug 2019

Discovery of molecular mechanism behind spread of leishmania infection

Researchers from the Institut National de la Recherche Scientifique (INRS) have made a breakthrough in understanding the reason behind the virulence of leishmania parasite. The leishmania parasite is responsible for causing leishmaniasis which affects over 12 million people across the globe and is a chronic parasitic disease.

14 Aug 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

Researchers make scientific breakthrough regarding Leishmania virulence strategy

A team from the Institut National de la Recherche Scientifique has made a scientific breakthrough regarding the virulence strategy employed by the Leishmania parasite to infect cells of the immune system.

12 Aug 2019

Study reveals surprising discoveries about poorly understood glioblastoma

Glioblastoma, a cancer that arises in the brain's supporting glial cells, is one of the worst diagnoses a child can receive. The grade IV, highly malignant tumor aggressively infiltrates healthy brain tissue, and most children die of the disease within one to two years of diagnosis, similar to adults.

12 Aug 2019

Lung mucosa plays big role in elderly's susceptibility to tuberculosis

Old lungs are not as capable as young lungs of fighting off an infection of the bacteria that causes tuberculosis, placing seniors at a greater risk of developing TB.

8 Aug 2019

Whole body vibration helps reduce inflammation, thanks to the gut microbiome

Whole body vibration appears to improve many symptoms of type II diabetes mellitus, wherein glucose and destructive inflammation shoots up. The procedure helps the body use glucose as an energy source, and at the same time, modify the microbiome to fight inflammation, a new study says.

6 Aug 2019