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Study finds different types of crystalloid fluids are equally effective for pediatric sepsis

A major study, led by researchers at Children's Hospital of Philadelphia, Nemours Children's Health, and Children's National Hospital and involving an extensive network of medical centers across the United States and abroad, found that different types of crystalloid fluid resuscitation were equally effective for staving off the most serious adverse kidney events after the treatment of pediatric patients with suspected septic shock.

25 Apr 2026

U.S. child mortality rates remain higher than other high-income nations

At every age, children in the United States die at higher rates than peers in other high-income nations, according to a new study from Children's Hospital of Philadelphia.

25 Apr 2026

New AI chatbot uses medical protocols to guide patient care decisions.

A new type of chatbot could reliably help people decide what to do about their symptoms - and do so based on guidance that is both medically sound and easy to understand.

25 Apr 2026

Researchers uncover new mechanism linking metabolism, immunity, and skeletal health

Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.

25 Apr 2026

Baby teeth reveal early metal exposure effects on brain

Researchers at the Icahn School of Medicine at Mount Sinai report that early-life exposure to common environmental metals may influence brain development and behavioral health more than a decade later.

25 Apr 2026

New biorepository approach advances research on sudden cardiac arrest

A cutting-edge University of Cincinnati College of Medicine study has shown how emergency medicine researchers can partner with community emergency medical services nationwide to investigate the causes of sudden cardiac arrest.

24 Apr 2026

AI-assisted doctors perform better in complex clinical decision making

Artificial intelligence-powered chatbots are getting pretty good at diagnosing some diseases, even when they are complex.

24 Apr 2026

Lower grip strength in early pregnancy linked to risk of hypertensive disorders of pregnancy

Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal mortality worldwide. In addition, HDP can lead to fetal growth restriction, preterm birth, and various long-term adverse health outcomes.

24 Apr 2026

COVID-19 patients with STEMI show higher one-year mortality rates

Findings from the North American COVID-19 Myocardial Infarction (NACMI) registry demonstrate significantly higher one-year mortality rates in patients with COVID-19 and ST-elevation myocardial infarction (STEMI) compared to patients with STEMI alone.

24 Apr 2026

Real-world study examines cangrelor dosing for antiplatelet bridging after PCI

A multi-center retrospective cohort study examined how cangrelor has been used in real-world clinical practice around the time of surgery following percutaneous coronary intervention (PCI) and described differences in outcomes seen with different dosing approaches.

24 Apr 2026

New mouse model reveals primary trigger of rare muscle disorder

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

24 Apr 2026

Long-term study supports tenofovir alafenamide for chronic hepatitis B

Tenofovir alafenamide (TAF) has demonstrated comparable efficacy to tenofovir disoproxil fumarate (TDF), with improved renal and bone safety, in Chinese participants with chronic hepatitis B enrolled in two Phase 3 trials.

24 Apr 2026

Influenza D shows strong potential to spill over to humans

The influenza D virus that researchers say has been flying under the radar since its detection in animals in 2011 can vigorously make copies of itself in human cells and lung tissue samples, a new study shows.

24 Apr 2026

Heatwaves and coldwaves linked to increase in major cardiovascular events

Heatwaves and coldwaves are associated with increases in major cardiovascular events that are exacerbated by air pollution.

24 Apr 2026

Air quality in infancy may fundamentally shape long-term immune development

Ambient air pollution is associated with respiratory infection burden in the first year of life, according to preliminary findings from the Immune Development in Early Life (IDEaL) Rome Cohort. Findings from the cohort will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Children with multiple chronic conditions show unique antibiotic exposure patterns

A new study from Boston Children's Hospital found that annual prescription rates increased non-linearly as children's underlying level of medical complexity increased. Frequent antibiotic use has associated risks, including increased likelihood of antibiotic-related complications (e.g., C. difficile) as well as the development of antibiotic resistance. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Study highlights the fragility of measles elimination in the United States

A new study examined measles vaccination coverage following a large postelimination outbreak, primarily affecting unvaccinated children. Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Negative parenting behaviors linked to gaming disorder in children with ADHD

A new Children's Hospital of Philadelphia study examines the relationship between parenting factors and gaming disorder in young children with attention deficit hyperactivity disorder (ADHD). Findings from the study will be presented during the Pediatric Academic Societies (PAS) 2026 Meeting, taking place April 24-27 in Boston.

24 Apr 2026

Many heart scans fail to provide clear diagnostic results

Thousands of patients sent for vital heart scans may be undergoing unnecessary first-line tests that fail to deliver clear answers - according to new research from the University of East Anglia.

23 Apr 2026