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Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs).

22 Aug 2025

Working-age adults with disabilities face much higher rates of loneliness

Working-age adults with disabilities experience far higher rates of loneliness than those without, according to a new study from researchers at the Brown University School of Public Health and the Warren Alpert Medical School.

22 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

In rapidly aging societies like Japan, the simple act of swallowing meals can be challenging for many. This condition, known as dysphagia, affects millions of people worldwide and can significantly deteriorate a person's quality of life.

22 Aug 2025

Urban heat and pollution linked to behavioral changes in children

Individuals living in urban cities are experiencing the combined effect of increasing temperatures and poor air quality, often referred to as the urban heat dome.

22 Aug 2025

New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans

Understanding how fat molecules are distributed and function in living organisms is key to uncovering mechanisms of aging, disease, and metabolism.

22 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

Excessive amounts of visceral fat tied to faster heart aging

Excessive amounts of visceral fat - the hidden fat surrounding organs - is linked with faster aging of the heart, a new study has found.

22 Aug 2025

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer's disease clinical trials, a new USC study finds.

22 Aug 2025

Epstein-Barr virus protein enhances cancer gene activity in HPV-positive cervical cells

A new research paper was published in Volume 16 of Genes & Cancer on August 6, 2025, titled "Epstein-Barr virus nuclear antigen 1 upregulates Derlin1 and PSMD10 expression in HeLa cells."

22 Aug 2025

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation

Despite advancements in diagnostic and therapeutic strategies, hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality.

22 Aug 2025

New core dataset advances standardized care and research in systemic lupus erythematosus

The European Alliance of Associations for Rheumatology - has published new recommendations on core datasets to be used in systemic lupus erythematosus (SLE).

22 Aug 2025

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Study finds no increased risk of death associated with higher intake of animal protein

Eating animal-sourced protein foods is not linked to a higher risk of death and may even offer protective benefits against cancer-related mortality, new research finds.

22 Aug 2025

AI detects early prostate cancer missed by pathologists

Men assessed as healthy after a pathologist analyses their tissue sample may still have an early form of prostate cancer.

22 Aug 2025

Insights into the clinical presentation and management of sellar chondrosarcomas

Chondrosarcomas are a malignant form of bone cancer that is composed of cartilage-forming tumor cells. Sellar chondrosarcomas, which occur in the sellar region at the base of the skull, are a very rare manifestation of chondrosarcoma, making up only around 0.2% of all tumors found in the skull.

22 Aug 2025

Natural products offer promising solutions in prosthodontics and oral implantology

Infection control is paramount in prosthodontics and oral implantology to prevent complications like denture stomatitis and peri-implantitis.

22 Aug 2025

Native Americans want to avoid past Medicaid enrollment snafus as work requirements loom

Jonnell Wieder earned too much money at her job to keep her Medicaid coverage when the covid-19 public health emergency ended in 2023 and states resumed checking whether people were eligible for the program.

22 Aug 2025

Aston Medical School secures NIHR funding for 12 academic clinical fellows

Aston Medical School has successfully bid for funding from the National Institute for Health and Care Research (NIHR) for 12 Academic Clinical Fellows.

22 Aug 2025

How generative AI scribes are reducing physician burnout

A new study led by Mass General Brigham researchers reveals that ambient documentation technologies – generative artificial intelligence scribes that record patient visits and draft clinical notes for physician review before incorporating them into electronic health records – led to significant reductions in physician burnout.

22 Aug 2025

Research News and Research

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

Working-age adults with disabilities face much higher rates of loneliness

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

Urban heat and pollution linked to behavioral changes in children

New microfluidics-based workflow enables high-resolution lipid imaging in C. elegans

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Excessive amounts of visceral fat tied to faster heart aging

Modest gift card boosts enrollment of low-income participants in Alzheimer’s registry

Epstein-Barr virus protein enhances cancer gene activity in HPV-positive cervical cells

ATOX1 drives hepatocellular carcinoma progression through c-Myb and PI3K/AKT activation

New core dataset advances standardized care and research in systemic lupus erythematosus

New method enables comprehensive analysis of metabolites in biological samples

Study finds no increased risk of death associated with higher intake of animal protein

AI detects early prostate cancer missed by pathologists

Insights into the clinical presentation and management of sellar chondrosarcomas

Natural products offer promising solutions in prosthodontics and oral implantology

Native Americans want to avoid past Medicaid enrollment snafus as work requirements loom

Aston Medical School secures NIHR funding for 12 academic clinical fellows

How generative AI scribes are reducing physician burnout

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

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