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Copper isotopes can help detect Alzheimer's aggregates in the brain

A proof-of-concept study conducted in a mouse model of Alzheimer's disease offers new evidence that copper isotopes can be used to detect the amyloid-beta protein deposits that form in the brains of people living with - or at risk of developing - Alzheimer's.

25 Nov 2020

BCG vaccination appears to trigger cross-reactive SARS-CoV-2-specific T cell response

Recently, researchers from the Monash University and Monash Medical Centre, Clayton, Victoria, Australia, investigated whether peptide sensitization using BCG can produce cross-reactive T cells specific to SARS-CoV-2. Their study is published on the preprint server, medRxiv.

24 Nov 2020

COVID-19: HLA class I genotypes and mortality

The study, published on the preprint server medRxiv, explores the ability of HLA class I molecules to mediate the outcome in COVID-19 patients.

24 Nov 2020

Furin inhibition may mitigate severe COVID-19, study finds

Dr. Kara Fitzgerald, a researcher at the Institute for Functional Medicine in the United States, has explained the role of furin protease in developing severe COVID-19 illness.

20 Nov 2020

Study provides new way to develop unconventional anticancer strategies

There is considerable interest in a new class of anticancer molecules that is currently still under investigation termed the cationic antimicrobial peptides (AMPs).

20 Nov 2020

"Escape mutations" could help SARS-CoV-2 evade immune attack

Researchers in the United States have identified mutations within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – that can reduce antibody binding to the virus, potentially mediating its escape from immune attack.

18 Nov 2020

Researchers explore potential role of oxytocin in modulating male sexual function

Hormones are key players of the endocrine system and have a major influence on our emotional and sexual wellbeing.

18 Nov 2020

Study sheds new light on how diabetes contributes to the development of Alzheimer’s disease

New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease.

18 Nov 2020

Certain regions in the retina are more affected by Alzheimer's disease, shows study

A study led by the Cedars-Sinai Department of Neurosurgery has identified certain regions in the retina - the lining found in the back of the eye - that are more affected by Alzheimer's disease than other areas.

18 Nov 2020

Affinity-Bead Assisted Mass Spectrometry for Proteomics

In this interview, Ghaith Hamza from AstraZeneca talks to News-Medical Life Sciences about the basic principles of Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS) and how Affi-BAMS can help target specific proteins for proteomic applications.

From Bruker Daltonics 16 Nov 2020

Research provides insight into how Alzheimer’s plaques form

We are beginning to better understand how 'amyloid-β' protein plaques form, which are implicated in degenerative brain diseases including Alzheimer's and Parkinson's diseases.

16 Nov 2020

Study could pave the way for potential urine test to diagnose liver fibrosis

Fifty fragments of proteins, termed peptides, have been identified in the urine of liver fibrosis patients in a new study that could pave the way for a potential diagnostic urine test for the condition if further validated.

16 Nov 2020

Consumption of teff grain boosts the composition, function of stomach microbiome

The seeds of a teff plant - which look similar to wheat - are tiny in stature, but they pack a nutritional wallop.

16 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

Harnessing proteomics could improve therapeutic approaches to COVID-19

A research group in India has recently described how the field of proteomics could be pivotal in helping to tackle the current coronavirus disease 2019 (COVID-19) pandemic.

15 Nov 2020

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

A new study published on the preprint server bioRxiv in November 2020 describes the virus's N protein as a promising epitope for serology.

12 Nov 2020

New process helps preserve viral vaccines without refrigeration

Ever receive a vaccination that seemed to burn a lot while it was injected? The vaccine solution likely contained a lot of salt or sugar - natural preservatives that help keep it stable, in addition to the cold temperature at which it was kept.

12 Nov 2020

PhoreMost and Oxford Biomedica collaborate to develop next-generation CAR-T cell therapies

PhoreMost Limited, the UK-based biopharmaceutical company dedicated to developing drugs against intractable disease targets, and Oxford Biomedica plc, a leading gene and cell therapy group, today announced that they have entered into a discovery collaboration to develop next-generation CAR-T cell therapies.

From PhoreMost 10 Nov 2020

Lateral flow test enables faster, accurate diagnosis of periprosthetic joint infection

The recently FDA-authorized alpha-defensin lateral flow test is a highly accurate, ten-minute test for diagnosis of periprosthetic joint infection (PJI) - a serious and costly complication of total joint replacement, reports a study in The Journal of Bone & Joint Surgery.

9 Nov 2020

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

A team of researchers has conducted a study suggesting that the majority of the global population is likely to have pre-existing T-cell immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.

9 Nov 2020

Peptides News and Research

Copper isotopes can help detect Alzheimer's aggregates in the brain

BCG vaccination appears to trigger cross-reactive SARS-CoV-2-specific T cell response

COVID-19: HLA class I genotypes and mortality

Furin inhibition may mitigate severe COVID-19, study finds

Study provides new way to develop unconventional anticancer strategies

"Escape mutations" could help SARS-CoV-2 evade immune attack

Researchers explore potential role of oxytocin in modulating male sexual function

Study sheds new light on how diabetes contributes to the development of Alzheimer’s disease

Certain regions in the retina are more affected by Alzheimer's disease, shows study

Affinity-Bead Assisted Mass Spectrometry for Proteomics

Research provides insight into how Alzheimer’s plaques form

Study could pave the way for potential urine test to diagnose liver fibrosis

Consumption of teff grain boosts the composition, function of stomach microbiome

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Harnessing proteomics could improve therapeutic approaches to COVID-19

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

New process helps preserve viral vaccines without refrigeration

PhoreMost and Oxford Biomedica collaborate to develop next-generation CAR-T cell therapies

Lateral flow test enables faster, accurate diagnosis of periprosthetic joint infection

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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