Aging News and Research

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Muscle hormone FGF21 linked to longer survival in ALS

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 9, 2025, titled "The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity."

18 Sep 2025

POT1 gene mutation linked to pulmonary fibrosis through telomere dysfunction

Idiopathic pulmonary fibrosis is a potentially fatal disease currently without treatment, in which lung tissue develops scarring and becomes stiff, making breathing increasingly difficult over time.

18 Sep 2025

Advanced imaging exposes breakdown in brain cell communication linked to Alzheimer’s

Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of Alzheimer's disease.

18 Sep 2025

Health care cuts threaten homegrown solutions to rural doctor shortages

Olivia Owlett chose to do her primary care residency in this Northern California college town largely because it faces many of the same health care challenges she grew up with.

18 Sep 2025

Resistance training may help preserve aging nerves

Simple resistance training may help counteract age-related nerve deterioration that puts seniors at risk of injuries from falls and other accidents, according to cross-institutional research led by Syracuse University postdoctoral researcher JoCarol Shields and Department of Exercise Science Professor Jason DeFreitas.

17 Sep 2025

Contact sports tied to hidden brain damage independent of CTE

This fall, tens of millions of people will be at risk for chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated head impacts from contact sports like football, soccer, and ice hockey, or military service.

17 Sep 2025

Repetitive head impacts trigger early brain changes in young athletes

Research supported by the National Institutes of Health (NIH) shows that repeated head impacts from contact sports can cause early and lasting changes in the brains of young- to middle-aged athletes.

17 Sep 2025

Cocoa extract supplements linked to reduced inflammation in older adults

Could cocoa extract supplements rich in cocoa flavanols reduce inflammation and, in turn, prevent age-related chronic diseases? In a new study from the COcoa Supplement and Multivitamin Outcomes Study (COSMOS), investigators from Mass General Brigham and their colleagues looked at changes in five age-related markers of inflammation among participants who received daily cocoa supplements over several years.

17 Sep 2025

High fat diet impairs memory formation through autophagy dysfunction

Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders.

17 Sep 2025

New AI-driven algorithm can accurately predict nearly 70% of hot flashes

University of Massachusetts Amherst researchers and scientists at Embr Labs, a Boston-based start-up, have developed an AI-driven algorithm that can accurately predict nearly 70% of hot flashes before they're perceived.

17 Sep 2025

CoQ10 shows promise in boosting female fertility by reviving aging eggs

Researchers reviewed evidence on Coenzyme Q10 (CoQ10) and found it may enhance mitochondrial function, improve oocyte quality, and counteract age-related fertility decline. The review highlights promising results from clinical, preclinical, and in vitro studies but calls for larger trials to confirm safety, dosing, and effectiveness.

16 Sep 2025

Age influences amyloid positivity in Parkinson's disease without dementia

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 6, 2025, titled "Age-related trends in amyloid positivity in Parkinson's disease without dementia."

16 Sep 2025

Study uncovers the tradeoff between fast immune defense and long-term inflammation

Some of our biggest threats can come in the tiniest forms-viruses and bacteria. Thankfully, we are born with a built-in defense system, our innate immune system that protects us in our youth but can turn against us as we age.

16 Sep 2025

Lifestyle changes show promise in preventing cognitive decline and Alzheimer’s disease

An estimated 7.2 million Americans over age 65 currently live with Alzheimer's disease (AD). That number is expected to nearly double to 13.8 million by 2060.

16 Sep 2025

Research challenges negative stereotypes about growing older

The aging population is one of the most important social issues of our time. However, discussions about aging are often one-sided and tinged with negativity.

16 Sep 2025

Population aging identified as largest contributor to the increasing burden of musculoskeletal disorders

Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.

16 Sep 2025

PM2.5 pollution linked to lung cancer shows sharp declines in the U.S. but not in China

The study highlights the need for stronger air quality measures as global lung cancer deaths linked to pollution are projected to rise, especially in China.

16 Sep 2025

Boosting PI31 to restore synaptic function and prevent neurodegeneration

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at the synapses-starts to fail.

16 Sep 2025

Daily meal timing influences longevity risk in adults, study reveals

Researchers analysing Aging Cell data from over 33,000 US adults found a U-shaped link between daily eating window length and mortality. Eating for 11–12 hours per day was tied to the lowest risk, while very short (<8h) or long (≥15h) windows raised death risk, especially in older and White participants.

15 Sep 2025

Study reveals how centenarians preserve youthful immune defenses

Researchers mapped immune cells from centenarians, their offspring, and younger controls across three cohorts using multi-omics single-cell profiling. They found that centenarians retain leaner helper pools but have enhanced cytotoxic and NK cell programs, along with reinforced NK–T communication networks.

15 Sep 2025