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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Nanostructures boost CRISPR delivery for genetic medicine

With the power to rewrite the genetic code underlying countless diseases, CRISPR holds immense promise to revolutionize medicine. But until scientists can deliver its gene-editing machinery safely and efficiently into relevant cells and tissues, that promise will remain out of reach.

2 Sep 2025

Landmark study maps mutational landscape of triple-negative breast cancer in African American women

Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women – but until now, they were underrepresented in genomic studies aimed at identifying the genetic mutations driving the disease.

1 Sep 2025

Genomic clues uncover early origins of multiple myeloma

A new study maps out the timeline of DNA damage for multiple myeloma, the second most common blood cancer.

1 Sep 2025

Can oral bacteria make heart disease worse?

The presence of viridans streptococci in coronary plaques indicates a role in atherosclerosis, potentially influencing heart disease outcomes.

1 Sep 2025

Ultra-processed foods affect sperm quality and metabolism even without extra calories

A controlled crossover trial in Cell Metabolism found that ultra-processed foods increase weight, fat mass, LDL:HDL cholesterol, and alter reproductive hormones in men, with some effects independent of calorie load. These diets also showed trends toward reduced sperm motility, shifts in pollutants, and transient inflammatory responses, highlighting risks beyond excess calories.

31 Aug 2025

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused eyebrows, short nose, upturned nose tip, and downturned mouth corners), growth retardation, small head (microcephaly), developmental delays, cognitive impairments, excess hair growth, and limb anomalies.

29 Aug 2025

Exploring the untapped potential of DNA glycosylation

Recent advancements in glycobiology have challenged the traditional understanding of molecular interactions, and a new study published in Engineering titled "Can DNA be glycosylated?" by Wei Wang further explores this emerging field.

29 Aug 2025

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). This study identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS.

29 Aug 2025

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease, according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

29 Aug 2025

Research sheds new light on depression’s biological roots

Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.

28 Aug 2025

AI and routine lab tests offer a more accurate prediction of genetic disease risk

When genetic testing reveals a rare DNA mutation, doctors and patients are frequently left in the dark about what it actually means.

28 Aug 2025

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.

27 Aug 2025

Abnormal fusion protein drives childhood brain tumor through condensate formation

A study looking at the biophysical properties of an abnormal protein driving cancer cells is giving scientists new therapeutic clues for how to treat ependymoma, the third most common childhood brain tumor.

27 Aug 2025

New discovery challenges the conventional understanding of myocardial infarction pathogenesis

A pioneering study by researchers from Finland and the UK has demonstrated for the first time that myocardial infarction may be an infectious disease.

27 Aug 2025

Faster biological aging associated with lower cognitive performance in later life

A new research paper was published in Volume 17, Issue 7 of Aging (Aging-US) on July 21, 2025, titled "Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study."

26 Aug 2025

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, USA, published August 26th in the open-access journal PLOS Biology.

26 Aug 2025

First comprehensive road map shows how the ovarian reserve forms in primates

UCLA scientists have developed the first comprehensive road map showing how the ovarian reserve forms in primates, providing crucial insights into women's health that could revolutionize treatments for infertility and hormonal disorders such as polycystic ovary syndrome, or PCOS.

26 Aug 2025

Mitochondria fight infection by starving parasites of essential nutrients

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DNA News and Research

Further Reading

Nanostructures boost CRISPR delivery for genetic medicine

Landmark study maps mutational landscape of triple-negative breast cancer in African American women

Genomic clues uncover early origins of multiple myeloma

Can oral bacteria make heart disease worse?

Ultra-processed foods affect sperm quality and metabolism even without extra calories

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Exploring the untapped potential of DNA glycosylation

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Research sheds new light on depression’s biological roots

AI and routine lab tests offer a more accurate prediction of genetic disease risk

Multi-analyte test accurately identifies brain cancers using cerebrospinal fluid

Abnormal fusion protein drives childhood brain tumor through condensate formation

New discovery challenges the conventional understanding of myocardial infarction pathogenesis

Faster biological aging associated with lower cognitive performance in later life

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

First comprehensive road map shows how the ovarian reserve forms in primates

Mitochondria fight infection by starving parasites of essential nutrients

Investigating toxicity of common bisphenol replacements in food packaging

Genetics and diet work together to shape daily rhythms of fat metabolism

Understanding the DNA Damage Response in Innate Immunity eBook

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