Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders.

9 Oct 2018

Study analyzes distribution of two cytokines in sections of carotid atherosclerotic plaques

Inflammation is currently a well-documented component of atheroslcerosis pathogenesis, which plays a role at each stage of the disease development.

6 Oct 2018

UConn chemists develop new antibiotic that can find and kill tuberculosis bacteria

Tuberculosis is a sneaky disease. The bacteria hide from antibiotics inside the very immune cells that are supposed to kill them, making treatment long and difficult. But in the November issue of ACS Infectious Diseases, UConn chemists report a new antibiotic that can find and kill tuberculosis bacteria where they hide.

4 Oct 2018

New tool provides improved in vivo imaging of atherosclerotic plaque development

Atherosclerosis, involving the buildup of plaque in the arteries and an associated reduction in the flow of blood, is a major feature of cardiovascular diseases.

28 Sep 2018

Axol's Human iPSC-derived Microglia for neuroimmunology research

Our Human iPSC-derived Microglia are suitable for a variety of applications including in vitro disease models, phenotypic screening and immunology studies.

From Axol Bioscience Ltd 27 Sep 2018

New nanoplatform technology may reverse drug-resistance in renal cell carcinoma

A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma.

24 Sep 2018

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

Cancer immunotherapy is a relatively new method of treating cancer and has succeeded with some refractory tumors. However, it doesn’t always work, why not?

21 Sep 2018

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Non-steroidal anti-inflammatory drugs, or NSAIDs, are commonly used as inflammation blockers worldwide. However, recent clinical data show these painkillers can have serious side effects that create some risk of heart attacks, strokes, and kidney or heart failure.

21 Sep 2018

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Cancer immunotherapy -- efforts to boost a patient's own immune system, allowing it to better fight cancer cells on its own -- has shown great promise for some previously intractable cancers.

21 Sep 2018

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

A scientific team found that the CXCL14 protein, associated with tumor progression and organogenesis, causes beneficial effects to metabolic diseases such as obesity and diabetes.

19 Sep 2018

Study aims to investigate risk factors for PPCs in surgical patients with gastric cancer

As one of the most common malignant tumors, gastric cancer occupies the second leading cause of cancer-related deaths worldwide with an increasing trend.

18 Sep 2018

New research shows evidence of soot from polluted air in placentas

Evidence of tiny particles of carbon, typically created by burning fossil fuels, has been found in placentas for the first time, in new research presented today at the European Respiratory Society International Congress.

17 Sep 2018

Research shows pollution is reaching the placenta

The evidence of air pollution – the soot and the fumes, has been seen in the lungs till date. In a new study, for the first time, the evidence of air pollution is seen in the placenta of a pregnant women.

16 Sep 2018

Breakthrough shows immune cells may play a role in schizophrenia

A type of immune cell called the “macrophages” are known to be one of the first soldiers of the body that can fight off infections and plays a role in maintaining immunity and in inflammation. According to latest research in schizophrenia, these macrophages can become altered and may cause changes in the brain leading to changes in the brain similar to schizophrenia.

14 Sep 2018

Pear-shaped body is healthier than apple shape

Whether we like it or not, everyone accumulates fat. For women, it usually accumulates around the hips, resulting in a pear-shaped look. In men, fat tends to build up around the abdomen, creating an apple shape.

13 Sep 2018

Sleep apnea can favor lung cancer growth in young individuals

A scientific study, conducted with animal models, states that sleep apnea can favor lung cancer growth in young individuals. Thus, aging would be a protecting factor against the fast tumor development, induced by this sleep alteration.

12 Sep 2018

Researchers unravel how Zika virus manipulates the human immune system

Macrophages are immune cells that are supposed to protect the body from infection by viruses and bacteria. Yet Zika virus preferentially infects these cells. Researchers at University of California San Diego School of Medicine have now unraveled how the virus shuts down the genes that make macrophages function as immune cells.

11 Sep 2018

CRI to bestow top honors on three scientists for contributions to cancer immunology and immunotherapy

The Cancer Research Institute, a nonprofit organization dedicated to the discovery and development of immunotherapies for all forms of cancer, will bestow its highest honors on three scientists who have made fundamental contributions to the fields of immunology and cancer immunotherapy.

11 Sep 2018

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers from Kanazawa University report in Journal of Neuroscience performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.

31 Aug 2018

Study provides insights into how harmful white blood cells form during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues.

31 Aug 2018

Macrophage News and Research

Further Reading

Prenatal inflammation may explain why some infants are more prone to neonatal sepsis

Study analyzes distribution of two cytokines in sections of carotid atherosclerotic plaques

UConn chemists develop new antibiotic that can find and kill tuberculosis bacteria

New tool provides improved in vivo imaging of atherosclerotic plaque development

Axol's Human iPSC-derived Microglia for neuroimmunology research

New nanoplatform technology may reverse drug-resistance in renal cell carcinoma

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

New research finds that MHC-II molecules have more influence on tumors than MHC-I

Study: CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases

Study aims to investigate risk factors for PPCs in surgical patients with gastric cancer

New research shows evidence of soot from polluted air in placentas

Research shows pollution is reaching the placenta

Breakthrough shows immune cells may play a role in schizophrenia

Pear-shaped body is healthier than apple shape

Sleep apnea can favor lung cancer growth in young individuals

Researchers unravel how Zika virus manipulates the human immune system

CRI to bestow top honors on three scientists for contributions to cancer immunology and immunotherapy

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Study provides insights into how harmful white blood cells form during tuberculosis

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