Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Understanding sex-based differences in immune system function

Many diseases affect men and women differently. Asthma tends to strike men earlier in life, yet more women develop asthma as they get older.

7 Aug 2025

Lupus Research Alliance awards early career scientists for innovative research

Today, the Lupus Research Alliance (LRA), the world's largest private funder of lupus research, announced the recipients of the 2025 Empowering Lupus Research (ELR) Career Development Award and Postdoctoral Award.

5 Aug 2025

Early immunotherapy shows promise for treating anti-IgLON5 disease

Researchers ask physicians to consider anti-IgLON5 disease if certain symptoms are present, as the only promising approach is early treatment.

5 Aug 2025

New treatment approach developed to prevent lupus nephritis

At the time when patients with lupus, or systemic lupus erythematosus (SLE), are diagnosed, approximately 15% to 30% will already have the inflammation-caused kidney disease lupus nephritis, which compromises kidney function and can lead to kidney failure.

4 Aug 2025

Living in rural areas early in life may increase risk of type 1 diabetes

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) suggests that living in a rural environment in the first five years of life could increase the risk of developing type 1 diabetes compared with living in urban environments.

4 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

UCSF research maps over 600 conditions linked to endometriosis

Records from millions of patients at UC health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.

31 Jul 2025

Genetic profiling offers hope for understanding multiple sclerosis risk

In a major step towards early detection, University of South Australia researchers are investigating the biology behind multiple sclerosis (MS) to help predict people's genetic risk of developing the disease, long before any symptoms appear.

29 Jul 2025

Gut mycobiota could help predict disability in multiple sclerosis

Gut fungal communities may impact multiple sclerosis severity, offering new insights into MS pathogenesis and potential microbiome-based treatment strategies.

29 Jul 2025

New research links age-related gene changes to symptom decline

UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.

29 Jul 2025

Aluminum vaccines cleared of long-term health risks

Findings from a cohort of 1.2 million children indicate aluminum-adsorbed vaccines do not raise the risk of autism, asthma, or autoimmune diseases.

17 Jul 2025

Egr-1 gene identified as crucial regulator of regulatory T cells in multiple sclerosis

Autoimmune diseases, such as multiple sclerosis (MS), inflammatory bowel disease (IBD), and rheumatoid arthritis (RA), affect millions of people worldwide.

11 Jul 2025

Myopenia identified as key contributor to muscle loss in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects individuals across all ages and genders.

11 Jul 2025

UCLA researchers discover new way to prevent immunotherapy-induced type 1 diabetes

A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs.

8 Jul 2025

Innovative bispecific antibody targets LAG-3 to treat autoimmune diseases

Immune checkpoint pathways regulate T cell function and play pivotal roles in the treatment of both cancer and autoimmune diseases.

7 Jul 2025

Neural stem cell grafts show promise for myelin repair in multiple sclerosis

A study led by Cambridge researchers has shed light on how neural stem cell grafts could help restore myelin in the central nervous system.

7 Jul 2025

Mapping the T cell response to Chikungunya virus

A new study, published recently in Nature Communications, offers the first-ever map of which parts of Chikungunya virus trigger the strongest response from the body's T cells.

3 Jul 2025

Engineered protein silences harmful T cells in autoimmune disease

An engineered protein turns off the kind of immune cells most likely to damage tissue as part of Type-1 diabetes, hepatitis, multiple sclerosis, shows a new study in mice.

1 Jul 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Novel combination therapy targets m6A pathway to combat joint erosion in rheumatoid arthritis

A recent study published in Engineering has shed light on a novel combination therapy for rheumatoid arthritis (RA) that significantly reduces bone destruction by targeting the m6A methylation pathway.

24 Jun 2025