Biomedicine News and Research

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New in vitro platform predicts drug toxicity, improving cancer treatment safety

Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle. To anticipate these risks, researchers at the University of Geneva (UNIGE) have developed in vitro models of the kidneys, liver, and heart - three organs particularly sensitive to such therapies.

16 Dec 2025

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents - and they've shown a possible route to reducing its likelihood.

10 Dec 2025

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab (Herceptin) and pertuzumab (Perjeta) delayed disease progression in patients with HER2-positive metastatic breast cancer, potentially extending time off chemotherapy, according to results from the phase III clinical trial HER2CLIMB-05 presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Human 3D brain model helps uncover mechanisms of preterm cerebral hemorrhage

In an article published in Advanced Science, the researchers identify how neural stem cells in preterm infants are injured following cerebral hemorrhage.

3 Dec 2025

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

An unusual public health policy in Wales may have produced the strongest evidence yet that a vaccine can reduce the risk of dementia.

2 Dec 2025

Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

Kinase inhibitors can accelerate the degradation of target proteins, study reveals

Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by attaching phosphate groups to other proteins.

26 Nov 2025

New imaging method reveals nanodomains inside ALS-linked protein droplets

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

26 Nov 2025

Study reveals early mandibular catch-up growth in infants with Robin sequence

Robin sequence is characterized by micrognathia, glossoptosis, and often cleft palate, leading to airway obstruction and feeding challenges.

26 Nov 2025

Dexamethasone shows potential to fight therapy-resistant breast cancer metastases

The drug dexamethasone supplements cancer treatments to alleviate side effects of chemotherapy such as nausea or inflammation.

24 Nov 2025

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

Pertussis, or whooping cough, remains a highly contagious respiratory infection caused by Bordetella pertussis. Despite inclusion of pertussis vaccines in immunization programs since the 1970s, outbreaks have re-emerged globally due to waning immunity and bacterial evolution.

19 Nov 2025

New transplant approach resets the immune system to stop Type 1 diabetes

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers.

18 Nov 2025

New human-cell bone marrow model offers alternative to animal experiments

Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types.

18 Nov 2025

Researchers develop novel computational method to interpret complex single-cell data

Researchers from Turku Bioscience Centre at the University of Turku, Finland, have developed a new computational method to interpret complex single-cell data. The method helps researchers identify and group cell types across samples.

17 Nov 2025

Machine learning model boosts success of liver transplants from circulatory death donors

There are more candidates on the waitlist for a liver transplant than there are available organs, yet about half the time a match is found with a donor who dies after cardiac arrest following the removal of life support, the transplant must be canceled.

13 Nov 2025

Study links common Epstein-Barr virus to autoimmune lupus

One of humanity's most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus erythematosus or, colloquially, lupus, Stanford Medicine investigators and their colleagues have found.

12 Nov 2025

Stanford scientists discover unexpected cancer resistance in aged mice

Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led by Stanford University researchers.

12 Nov 2025

Personalized prehabilitation reduces the risk of surgical complications

The weeks leading up to a major surgery can be a time of uncertainty and worry for patients, many of whom anticipate the need for rehabilition to get back on their feet.

12 Nov 2025

New expert recommendations redefine exercise as therapy for children with asthma

Asthma is one of the most common chronic respiratory diseases among children, affecting nearly 475 million globally. For decades, exercise was discouraged due to the risk of triggering wheezing and breathlessness, known as exercise-induced bronchoconstriction (EIB).

11 Nov 2025

Study reveals tumor defense mechanisms in colorectal cancer

Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies-treatments that reactivate the immune system to attack tumor cells-have transformed the treatment of many types of cancer.

7 Nov 2025

Biomedicine News and Research

New in vitro platform predicts drug toxicity, improving cancer treatment safety

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Human 3D brain model helps uncover mechanisms of preterm cerebral hemorrhage

Shingles vaccine may benefit individuals already diagnosed with dementia, new study finds

Blocking a ‘gerozyme’ reverses cartilage loss in mice

Kinase inhibitors can accelerate the degradation of target proteins, study reveals

New imaging method reveals nanodomains inside ALS-linked protein droplets

Study reveals early mandibular catch-up growth in infants with Robin sequence

Dexamethasone shows potential to fight therapy-resistant breast cancer metastases

Expert panel recommends new antibiotic strategies for resistant Bordetella pertussis

New transplant approach resets the immune system to stop Type 1 diabetes

New human-cell bone marrow model offers alternative to animal experiments

Researchers develop novel computational method to interpret complex single-cell data

Machine learning model boosts success of liver transplants from circulatory death donors

Study links common Epstein-Barr virus to autoimmune lupus

Stanford scientists discover unexpected cancer resistance in aged mice

Personalized prehabilitation reduces the risk of surgical complications

New expert recommendations redefine exercise as therapy for children with asthma

Study reveals tumor defense mechanisms in colorectal cancer

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