Immunomodulatory News and Research

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Engineering safe and effective vaccinia virus vectors for next-generation vaccines

Announcing a new article publication for Zoonoses journal. Vaccinia virus (VACV) confers cross-protective immunity against the variola virus, the causative agent of smallpox, and has therefore been extensively exploited as a preventive vaccine. Despite the global eradication of smallpox in the 1980s, research efforts involving VACV have continued due to the potential threat of the variola virus being used as a bioweapon, which poses grave risks to human health.

14 Feb 2025

Dietary intervention restores gut microbiome and offers protection against chronic diseases

Findings indicate that a microbiome restoration diet improves gut health and reduces chronic disease markers, highlighting its cardiometabolic benefits.

27 Jan 2025

Azvudine beats paxlovid in reducing COVID-19 deaths

In hospitalized COVID-19 patients, azvudine shows lower all-cause mortality and fewer adverse events than Paxlovid, with added antitumor effects observed.

21 Jan 2025

Specialized bone marrow niches reveal secrets of immune tolerance

Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their regenerative potential and therapeutic relevance.

2 Jan 2025

New eye drop treatment offers hope for dry AMD patients

Age-related macular degeneration (AMD) is the leading cause of vision loss in individuals over 65, characterized by abnormal changes in the macular, resulting in reduced vision and distorted objects.

23 Dec 2024

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

This study reveals how SARS-CoV-2 infection significantly alters human milk composition, while COVID-19 vaccination causes minimal, transient changes, underscoring the safety of breastfeeding during vaccination.

19 Dec 2024

Australian researchers discover potential lifeline for premature babies

Australian researchers have discovered a potential new lifeline for the tiniest and most vulnerable newborns. Scientists at Monash Children's Hospital have successfully collected and reinfused umbilical cord blood cells in extremely premature babies, offering a glimmer of hope for preventing brain injuries.

18 Dec 2024

Exploring the potential of MSCs in cancer therapy

A new review was published in Oncotarget's Volume 15 on November 22, 2024, entitled "Mesenchymal stem cells – the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists."

4 Dec 2024

Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative breast cancer (TNBC). The findings identify nine spatial archetypes and gene signatures linked to immunotherapy response and patient outcomes.

2 Dec 2024

Study uncovers diversity of cancer-associated fibroblasts in skin cancer

A study at MedUni Vienna's Department of Dermatology provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment.

19 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Comparing camel, cow, and goat milk: Which is best for diabetes and heart health?

Camel milk's nutritional profile supports diabetes and heart health, offering superior metabolic benefits over cow and goat milk for chronic disease management.

13 Nov 2024

Exploring the anticancer potential of medicinal plants

Cancer remains one of the leading global causes of mortality, with an estimated increase in cases due to lifestyle, environmental, and genetic factors.

8 Nov 2024

Understanding the role of neuroimmune cells in brain health and disease

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

6 Nov 2024

Review: The multifaceted roles of bilirubin in liver health and disease

Bilirubin, the byproduct of hemoprotein breakdown, particularly hemoglobin, is a critical marker in diagnosing, prognosing, and managing liver diseases.

6 Nov 2024

How a ketogenic diet could reduce autoimmune disease severity through host-microbiome interactions

This study uncovers the ketogenic diet's effects on the microbiome, revealing its potential to mitigate autoimmune diseases through metabolic pathways.

6 Nov 2024

Novel class of encrypted peptides offers hope against drug-resistant bacteria

In a significant advance against the growing threat of antibiotic-resistant bacteria, researchers have identified a novel class of antimicrobial agents known as encrypted peptides, which may expand the immune system's arsenal of tools to fight infection.

28 Oct 2024

Immunomodulatory News and Research

Engineering safe and effective vaccinia virus vectors for next-generation vaccines

Dietary intervention restores gut microbiome and offers protection against chronic diseases

Azvudine beats paxlovid in reducing COVID-19 deaths

Specialized bone marrow niches reveal secrets of immune tolerance

New eye drop treatment offers hope for dry AMD patients

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

Australian researchers discover potential lifeline for premature babies

Exploring the potential of MSCs in cancer therapy

Spatial transcriptomics uncovers new treatment paths for triple-negative breast cancer

Study uncovers diversity of cancer-associated fibroblasts in skin cancer

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Comparing camel, cow, and goat milk: Which is best for diabetes and heart health?

Exploring the anticancer potential of medicinal plants

Understanding the role of neuroimmune cells in brain health and disease

Review: The multifaceted roles of bilirubin in liver health and disease

How a ketogenic diet could reduce autoimmune disease severity through host-microbiome interactions

Novel class of encrypted peptides offers hope against drug-resistant bacteria

How do animal and plant-based milks affect gut health?

Novel delivery platform enhances effectiveness of cancer immunotherapy and reduces side effects

Evolution of vaccine adjuvants from empirical discovery to rational design

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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