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Novel cholesterol removal strategy shows potential benefits post-heart attack

The first trial of a novel strategy for removing cholesterol from patients' arteries did not reduce the risk of death, heart attack or stroke within three months of a prior heart attack, according to research presented at the American College of Cardiology's Annual Scientific Session. However, the findings suggest that the strategy may be beneficial with longer follow-up.

8 Apr 2024

Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

In patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran reduced triglyceride levels by an average of 74% after 24 weeks of use without causing any significant safety concerns, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study shows promise of zilebesiran injection in reducing systolic blood pressure

A single subcutaneous injection of the investigational drug zilebesiran, when added to existing treatment with a standard antihypertensive medication, reduced systolic blood pressure by between 4 to 12 mmHg on average at three months in patients whose blood pressure had remained uncontrolled despite compliance with their medication regimen, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Heavy alcohol use linked to increased risk of Type 2 diabetes in middle-aged adults

Heavy alcohol use may increase middle-aged adults' risk of developing Type 2 diabetes, according to research to be presented this week at the American Physiology Summit in Long Beach, California.

7 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Dietary choices are linked to higher rates of preeclampsia among Latinas

For pregnant Latinas, food choices could reduce the risk of preeclampsia, a dangerous type of high blood pressure, and a diet based on cultural food preferences, rather than on U.S. government benchmarks, is more likely to help ward off the illness, a new study shows.

5 Apr 2024

Gene defect associated with argininosuccinic aciduria corrected using CRISPR-Cas9 technique

Argininosuccinate lyase deficiency (ASLD), also known as argininosuccinic aciduria, is a disease that has been enriched in the Finnish genetic heritage.

4 Apr 2024

From gut to mind: Exploring prebiotics and probiotics as dual fighters against depression and obesity

The interactions between depression and nutrition, coupled with exercise.

4 Apr 2024

Study identifies genetic variants with profound impact on obesity risk

A study led by Medical Research Council (MRC) researchers has identified genetic variants in two genes that have some of the largest impacts on obesity risk discovered to date.

4 Apr 2024

Telemedicine doubles HCV treatment success for opioid use disorder patients

People with opioid use disorder who have hepatitis C virus (HCV) were twice as likely to be successfully treated and cured from HCV if they received facilitated telemedicine treatment at their opioid treatment program (OTPs) than if they were referred off-site to another provider.

3 Apr 2024

Does IBD affect cancer risk?

Research suggests no strong genetic link between inflammatory bowel disease and increased cancer risk, with specific exceptions in European populations for Crohn's disease and ulcerative colitis.

3 Apr 2024

Study explores how cannabis use affects breast milk and lactation

Study reviews the impact of cannabis use during pregnancy and lactation, highlighting potential changes in breast milk composition and lactation due to cannabinoid effects.

3 Apr 2024

New malaria vaccine strain shows promise in preclinical trials

In a report published on March 21, 2024 in EMBO Molecular Medicine (A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion) investigators at Seattle Children's Research Institute and Sanaria Inc. describe the development of a whole malaria parasite vaccine strain that infects the liver, develops to the late liver stage, and then gets completely stuck and cannot burst out of the liver to cause symptomatic blood infection.

2 Apr 2024

Eating soy products linked to lower cancer risk, study finds

Soy product consumption, particularly tofu and soymilk, is linked to a reduced risk of certain cancers, highlighting the dietary factor's potential protective effect against the disease.

1 Apr 2024

Rare variants in the YKT6 gene cause new neurological disorder, study finds

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

1 Apr 2024

Tuberculosis linked to increased risk of cancer, study finds

A population-wide observational study to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows an association between tuberculosis (TB) and cancer, with those with current or previous TB more likely to have a diagnosis of a variety of cancers, including lung, blood, gynaecological and colorectal cancers.

1 Apr 2024

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have identified distinct molecular signatures associated with the clinical signs of sepsis that could provide more accurate diagnosis and prognosis of sepsis, as well as help to target specific therapies at patients who would benefit most, according to new research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April).

30 Mar 2024

Vegan diet benefits individuals with type 1 diabetes, study shows

A low-fat vegan diet rich in fruits, vegetables, grains, and beans reduces insulin needs and improves insulin sensitivity and glycemic control in people with type 1 diabetes, according to a first-of-its-kind study by the Physicians Committee for Responsible Medicine published in Clinical Diabetes.

29 Mar 2024

Uncovering gender-specific genetic alterations in cancer

Recent research spearheaded by Chunmei Cui at the State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, China, casts a new light on the nuanced interplay between gender and cancer, uncovering significant sex-specific disparities in copy number alterations (CNA) across various cancer types.

29 Mar 2024

Study reveals crucial insights into the ocular effects of Zika virus infection during pregnancy

A groundbreaking study published in the journal iScience presents crucial insights into the ocular effects of Zika virus infection during pregnancy and offers promising avenues for therapeutic intervention.

28 Mar 2024

Liver News and Research

Novel cholesterol removal strategy shows potential benefits post-heart attack

Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

Study shows promise of zilebesiran injection in reducing systolic blood pressure

Heavy alcohol use linked to increased risk of Type 2 diabetes in middle-aged adults

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Dietary choices are linked to higher rates of preeclampsia among Latinas

Gene defect associated with argininosuccinic aciduria corrected using CRISPR-Cas9 technique

From gut to mind: Exploring prebiotics and probiotics as dual fighters against depression and obesity

Study identifies genetic variants with profound impact on obesity risk

Telemedicine doubles HCV treatment success for opioid use disorder patients

Does IBD affect cancer risk?

Study explores how cannabis use affects breast milk and lactation

New malaria vaccine strain shows promise in preclinical trials

Eating soy products linked to lower cancer risk, study finds

Rare variants in the YKT6 gene cause new neurological disorder, study finds

Tuberculosis linked to increased risk of cancer, study finds

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Vegan diet benefits individuals with type 1 diabetes, study shows

Uncovering gender-specific genetic alterations in cancer

Study reveals crucial insights into the ocular effects of Zika virus infection during pregnancy

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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