Aging News and Research

RSS

Young human serum requires bone marrow for skin rejuvenation effects

A new research paper featured on the cover of Volume 17, Issue 7 of Aging (Aging-US) was published on July 25, 2025, titled "Systemic factors in young human serum influence in vitro responses of human skin and bone marrow-derived blood cells in a microphysiological co-culture system."

1 Aug 2025

The vicious circle of aging and metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD) and aging are locked in a vicious circle: senescence of liver cells accelerates fat accumulation, inflammation and fibrosis, while chronic steatosis in turn hastens hepatic decline.

1 Aug 2025

This test can see a heart attack in your future

A long list of Lynda Hollander's paternal relatives had heart disease, and several had undergone major surgeries. So when she hit her mid-50s and saw her cholesterol levels creeping up after menopause, she said, "I didn't want to take a chance."

1 Aug 2025

Copper may protect brain health after stroke

Research shows dietary copper intake boosts cognitive function in older adults, particularly those with a stroke history, highlighting its neuroprotective role.

1 Aug 2025

Salk Institute's ShortStop revolutionizes genetic search

Proteins sustain life as we know it, serving many important structural and functional roles throughout the body. But these large molecules have cast a long shadow over a smaller subclass of proteins called microproteins.

1 Aug 2025

Researchers uncover PSAT1 gene as key to heart repair post-heart attack

Heart attacks remain a leading cause of death and disability worldwide. The permanent loss of heart muscle cells-known as cardiomyocytes-and the heart's limited regenerative capacity often led to chronic heart failure.

1 Aug 2025

Study sheds light on molecular mechanisms of brain aging

Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells – a process called "proteostasis," or protein homeostasis.

31 Jul 2025

Chemotherapy treatment linked to lasting cognitive changes in rats

Researchers at The City College of New York have linked chemotherapy treatment to lasting cognitive changes in rats – potentially shading light, for the first time, on cognitive problems some cancer survivors experience long after treatment ends.

31 Jul 2025

Selective impairment of translation contributes to brain aging in killifish

Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study.

31 Jul 2025

Metformin lowers blood sugar by acting on brain pathways

Although metformin has been the go-to medication to manage type 2 diabetes for more than 60 years, researchers still do not have a complete picture of how it works.

31 Jul 2025

Most US adults have older heart age than actual age

Most U.S. adults have a "heart age" several years older than their chronological age - sometimes by more than a decade.

30 Jul 2025

Immune cells migrate from the gut to breast during pregnancy and lactation

Of the 3.6 million babies born in the United States each year, around 80 percent begin breastfeeding in their first month of life.

30 Jul 2025

A 15-year study reveals which diets best protect your brain and heart in later life

Older adults who consistently followed healthy dietary patterns, especially AHEI, MIND, and AMED, accumulated chronic diseases more slowly over 15 years. Diets high in pro-inflammatory foods were linked to a faster buildup of multimorbidity, particularly in cardiovascular and neuropsychiatric conditions.

29 Jul 2025

New RNA therapy reverses symptoms of progeria in mouse models

Children who develop deep wrinkles, stunted growth, and rapidly aging bones and blood vessels as early as 1 to 2 years of age may be suffering from Hutchinson-Gilford Progeria Syndrome (HGPS), a rare and incurable genetic disorder that affects approximately one in eight million people.

29 Jul 2025

Senescent macrophages emerge as key drivers of tumor progression

Macrophages are versatile immune cells, tasked with cleaning up pathogens and maintaining tissue health.

29 Jul 2025

Researchers map key mechanism for bladder function

Urinary incontinence is a devastating condition affecting over 33 million Americans, according to the National Association for Continence, leading to significant adverse impacts on patients' mental health and quality of life. Disorders of urination are also a key feature of all neurological disorders.

29 Jul 2025

New research links age-related gene changes to symptom decline

UCSF researchers have found that certain antiviral genes become less active over time in lupus, revealing why some patients see their symptoms fade as they age.

29 Jul 2025

Moderate coffee and tea habits linked to sharper thinking in seniors

Moderate coffee intake and both moderate and high tea consumption are associated with a slower decline in fluid intelligence among older adults over nearly a decade. High coffee intake, however, is linked to a faster decline in cognitive function.

28 Jul 2025

Brain’s blood vessels and immune cells play key role in Alzheimer’s and stroke

The brain's health depends on more than just its neurons. A complex network of blood vessels and immune cells acts as the brain's dedicated guardians-controlling what enters, cleaning up waste, and protecting it from threats by forming the blood-brain barrier.

28 Jul 2025

New software predicts cancer cell behavior to advance treatment

In the same vein as weather forecast models that predict developing storms, researchers now have developed a method to predict the cell activity in tissues over time.

28 Jul 2025