Efficacy News and Research

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A collaborative initiative by ISSCR toward responsible adoption of stem cell models

Advances in human stem cell-derived disease models have the potential to augment our predictive power for the efficacy and safety of new drugs.

27 May 2025

Understanding cow’s milk allergy in breastfed infants

Cow’s milk allergy (CMA) affects up to 2.2% of infants, with a complex interplay of immunological mechanisms, allergen transfer via breast milk, and variable responses to maternal elimination diets. Current evidence challenges the routine use of maternal dietary restrictions, highlighting the need for precise diagnosis and further research.

27 May 2025

Mutation profiles and clinicopathological correlations in lung squamous cell carcinoma

Lung Squamous cell carcinoma (LSCC) represents the second most common non-small cell lung cancer.

26 May 2025

Innovative approaches to managing diabetic wounds with smart bioactive dressings

A recent study published in Engineering delves into the advancements in wound management, specifically focusing on microenvironment-sensitive bioactive dressings for diabetic wounds. Diabetic wounds (DWs) are a major complication of diabetes mellitus.

26 May 2025

Novel immune cells identified as potential target for tuberculosis vaccines

There is no highly effective vaccine against tuberculosis (TB), which remains an infection of global concern.

26 May 2025

New guideline aims to help primary care clinicians diagnose and treat hypertension

A new guideline to diagnose and treat hypertension is aimed at helping primary care clinicians, including family physicians, nurses, nurse practitioners, and pharmacists, manage the disease.

26 May 2025

New cryogenic mass spectrometry approach reveals inner structure of lipid nanoparticles

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues.

23 May 2025

Radiometer expands clinical intelligence software suite with AI-enabled tool to improve triage in overcrowded Emergency Departments

With TriageGO, Radiometer introduces an innovative AI tool that streamlines patient prioritization in emergency settings, improving care efficiency and safety.

From Radiometer Medical 23 May 2025

Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

23 May 2025

Powerful new toolkit targets vision loss in advanced retinal degeneration

Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye-the photoreceptors-die due to mutations in genes needed for their function and survival.

23 May 2025

Researchers prolong ketamine’s antidepressant benefits to two months

Roughly 10 percent of the U.S. population is afflicted with major depressive disorder at any given time, and up to 20 percent will exhibit MDD symptoms over their lifetimes.

22 May 2025

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Acute coronary syndrome (ACS) in patients with SARS-CoV-2 infection represents a critical intersection of viral-induced inflammation and cardiovascular pathology.

22 May 2025

Catalpol shows neuroprotective effects across multiple neurologic conditions

Announcing a new publication for Acta Materia Medica journal. Neurologic disorders are the leading cause of illness and disability as a result of increased life expectancy and global population aging, highlighting the urgent need and great challenge for discovering neuroprotective agents with better efficacy and minimal side-effects.

22 May 2025

Gut bacteria and diet found to affect cancer treatment outcomes

A Ludwig Cancer Research study has uncovered a surprising link between diet, intestinal microbes and the efficacy of cancer therapy.

22 May 2025

Reducing Polypharmacy with Innovative Drug Formulation Technologies

Discover how hot melt extrusion supports polypharmacy reduction and novel therapies for stroke and snakebite with expert insights.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 22 May 2025

Insulin resistance in the brain may link Alzheimer’s and epilepsy

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.

22 May 2025

Reduced monitoring after stroke found safe for low risk patients

Halving the number of times vital signs and neurological function are checked in low-risk patients after treatment for acute ischaemic stroke does not compromise care or recovery, according to new findings presented at the 11th European Stroke Organisation Conference in Helsinki, Finland.

22 May 2025

SwRI designs bed netting systems for mosquito-based malaria control

Southwest Research Institute tapped into its drug formulation and manufacturing expertise to fabricate two bed netting prototypes targeting malaria-causing blood parasites.

21 May 2025

Culturally tailored program helps UK seniors sit less and move more

A UK study found that a 12-week intervention to reduce sedentary behavior was well accepted by ethnically diverse older adults. Participants perceived benefits and suggested culturally tailored, home-based approaches for future health programs.

21 May 2025

Microplastics in ultra-processed foods may fuel mental health risks, experts warn

New research highlights a possible link between microplastics in ultra-processed foods and rising rates of depression, anxiety, and sleep problems. Experts call for urgent investigation as microplastic accumulation in the human brain increases alongside ultra-processed food intake.

21 May 2025

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Efficacy News and Research

A collaborative initiative by ISSCR toward responsible adoption of stem cell models

Understanding cow’s milk allergy in breastfed infants

Mutation profiles and clinicopathological correlations in lung squamous cell carcinoma

Innovative approaches to managing diabetic wounds with smart bioactive dressings

Novel immune cells identified as potential target for tuberculosis vaccines

New guideline aims to help primary care clinicians diagnose and treat hypertension

New cryogenic mass spectrometry approach reveals inner structure of lipid nanoparticles

Radiometer expands clinical intelligence software suite with AI-enabled tool to improve triage in overcrowded Emergency Departments

Aging metabolism reduces effectiveness of CAR-T cell therapy

Powerful new toolkit targets vision loss in advanced retinal degeneration

Researchers prolong ketamine’s antidepressant benefits to two months

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Catalpol shows neuroprotective effects across multiple neurologic conditions

Gut bacteria and diet found to affect cancer treatment outcomes

Reducing Polypharmacy with Innovative Drug Formulation Technologies

Insulin resistance in the brain may link Alzheimer’s and epilepsy

Reduced monitoring after stroke found safe for low risk patients

SwRI designs bed netting systems for mosquito-based malaria control

Culturally tailored program helps UK seniors sit less and move more

Microplastics in ultra-processed foods may fuel mental health risks, experts warn

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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