Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

A team led by researchers at Baylor College of Medicine found that a screening method known as untargeted metabolomics profiling can improve the diagnostic rate for inborn errors of metabolism, a group of rare genetic conditions, by about seven-fold when compared to the traditional metabolic screening approach.

12 Jul 2021

Novel method of gene therapy promises to transform the treatment of rare genetic disorder

A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities.

12 Jul 2021

Antiviral activity of long-chain polyphosphates against SARS-CoV-2 infection

A new study has been published in Science Signaling that has examined the potential role that long-chain inorganic polyphosphates (polyPs) play against SARS-CoV-2 infection.

9 Jul 2021

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

While Delta (B.1.617.2) has overtaken Alpha (B.1.1.7) as the dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in the United States, Alpha remained a force to be reckoned with in New York City earlier this year. New research published on the preprint medRxiv* server details breakthrough infections in vaccinated and unvaccinated individuals living in New York City.

9 Jul 2021

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers in the United States have conducted a study suggesting that individuals fully vaccinated against coronavirus disease 2019 (COVID-19) who develop breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less likely to transmit the virus to others than unvaccinated infected individuals.

8 Jul 2021

Scientists discover drug candidates for treating liver fibrosis among pesticides

Skoltech biologists and their colleagues from Koltzov Institute of Developmental Biology, Russia, and the Chemistry Department of Taras Shevchenko University in Ukraine have discovered fairly unlikely drug candidates for treating liver fibrosis and other pathologies -- among pest control chemicals.

8 Jul 2021

Genetic analysis method reveals causal association between thyroid function and serum lipid metabolism

Thyroid hormones are amino acid-based molecules produced by the thyroid gland. Involved in direct or indirect regulation of key metabolic pathways, these molecules play critical roles in the development and normal functioning of the body.

8 Jul 2021

How SARS-CoV-2 has evolved over the course of the pandemic

In an effort to understand the ongoing evolution of the SARS-CoV-2 genome, researchers constructed a phylogenetic tree of all available SARS-CoV-2 genomes.

7 Jul 2021

Skin pigmentation mechanism confers major protection against UV-related cancers

A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).

7 Jul 2021

Vaccinate big cats? New report shows SARS-CoV-2 Delta variant infecting endangered lions

There is evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infecting animals such as ferrets, fruit bats, and cats. New research led by Vijendra Pal Singh from the ICAR-National Institute of High Security Animal Disease in India suggests it might be time to vaccinate the big cats as well. Their report details SARS-CoV-2 infection in nine Asiatic lions caused by the SARS-CoV-2 Delta variant (B.1.617.2).

7 Jul 2021

Scientists unravel how cell death is initiated on a molecular level

The death of cells is well regulated. If it occurs too much, it can cause degenerative diseases. Too little, and cells can become tumors.

6 Jul 2021

Janssens’ COVID-19 vaccine effective against SARS-CoV-2 Delta variant

Researchers in the Netherlands have conducted a study showing that Janssen’s Ad26.COV2.S coronavirus disease 2019 (COVID‐19) vaccine was effective against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among eight individuals.

4 Jul 2021

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

A team of researchers recently demonstrated that mutations in the S protein of SARS-CoV-2 select for amino acid changes that result in a more stable protein than would otherwise be expected.

1 Jul 2021

Study offers clues for earlier diagnosis of folate deficiency

As many expectant mothers know, getting enough folate is key to avoiding neural tube defects in the baby during pregnancy. But for the individuals who carry certain genetic variants, dealing with folate deficiency can be a life-long struggle which can lead to serious neurological and heart problems and even death.

1 Jul 2021

Could peridomestic mammals act as zoonotic reservoirs for SARS-CoV-2?

In new research from researchers in the USA and Australia peridomestic mammals, which live in and around human habitations, have been investigated to ascertain how SARS-CoV-2 can affect species external to, but in close proximity to, the human population.

1 Jul 2021

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

To this end, a recent study published in Nature Structural & Molecular Biology discusses the structures of the SARS-CoV-2 ORF3a using cryo-electron microscopy (cryo-EM).

30 Jun 2021

Study highlights changes within SARS-CoV-2 variants that could be exploited to design effective inhibitors

A computational study that analyzes and explores the time-based structures of the SARS-CoV-2 variants with specific spike (S) protein mutations is discussed here.

30 Jun 2021

Alpha variant mutations help SARS-CoV-2 overcome evolutionary weaknesses

The study, published in the journal Cell Reports, showed that the mutations in the virus, particularly the deletion of two amino acids H69/V70 seen in the Alpha variant (B.1.1.7), enables the virus to overcome weaknesses as it evolves.

30 Jun 2021

Researchers identify specific biomarkers for coronary microvascular disease

Although cardiovascular disease is the main cause of illness among women in the U.S., certain conditions such as coronary microvascular disease (CMD) cannot be easily diagnosed. In a new study, researchers at the University of Illinois Urbana-Champaign have identified specific biomarkers for CMD, which might reduce future hospitalizations.

30 Jun 2021

Scientists outline new target for treating type 2 diabetes

This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition.

30 Jun 2021

Amino Acid News and Research

Further Reading

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

Novel method of gene therapy promises to transform the treatment of rare genetic disorder

Antiviral activity of long-chain polyphosphates against SARS-CoV-2 infection

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Scientists discover drug candidates for treating liver fibrosis among pesticides

Genetic analysis method reveals causal association between thyroid function and serum lipid metabolism

How SARS-CoV-2 has evolved over the course of the pandemic

Skin pigmentation mechanism confers major protection against UV-related cancers

Vaccinate big cats? New report shows SARS-CoV-2 Delta variant infecting endangered lions

Scientists unravel how cell death is initiated on a molecular level

Janssens’ COVID-19 vaccine effective against SARS-CoV-2 Delta variant

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

Study offers clues for earlier diagnosis of folate deficiency

Could peridomestic mammals act as zoonotic reservoirs for SARS-CoV-2?

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

Study highlights changes within SARS-CoV-2 variants that could be exploited to design effective inhibitors

Alpha variant mutations help SARS-CoV-2 overcome evolutionary weaknesses

Researchers identify specific biomarkers for coronary microvascular disease

Scientists outline new target for treating type 2 diabetes

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The Critical Role of Sample Storage in Drug Discovery and Development

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