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New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Novel algorithm predicts on-road driving ability in older adults with cognitive concerns

As the world's population ages, so does the proportion of older drivers on the road. Safe driving requires adequate memory, perceptual and motor skills, and executive function abilities.

24 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Insilico Medicine leadership team shares insights on AI-powered healthcare innovation

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announces that the co-CEOs of the company – Alex Zhavoronkov, PhD, and Feng Ren, PhD – will be attending the 15th Annual Meeting of the New Champions, also known as Summer Davos hosted by the World Economic Forum, in Dalian, China, from 25 to 27 June 2024.

21 Jun 2024

Anakinra shows promise in reducing symptoms in patients with Sanfilippo syndrome

As a neurodegenerative disease characterized by childhood onset dementia, Sanfilippo syndrome causes immense suffering in many ways, including pain, loss of speech, extreme agitation, and distress, gastrointestinal symptoms, and profound sleep disturbance.

21 Jun 2024

New challenges in cancer care: cardiovascular disease and environmental factors

Preclinical and epidemiologic evidence linking air pollution to cardio-oncology.

21 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

Yeast-fermented bread shows promise in preventing asthma symptoms

The effects of a functional bread fermented with yeast (Saccharomyces cerevisiae) in asthma prevention.

20 Jun 2024

Enlarged prostate medications may also decrease the risk for dementia with Lewy bodies

A new study suggests that certain drugs commonly used to treat enlarged prostate may also decrease the risk for dementia with Lewy bodies (DLB).

19 Jun 2024

Researchers develop cutting-edge smart bandages for improved wound healing

Chronic wounds, which include diabetic ulcers, surgical wounds, pressure injuries, and other problems, are deadlier than many people realize.

17 Jun 2024

Tufts' new ingestible microbiome sampling pill completes preclinical trials

Significant progress has been made at Tufts University School of Engineering in the development of a small device, about the size of a vitamin pill, that can be swallowed and passed through the gastrointestinal tract to sample the full inventory of microorganisms in an individual's gastro-intestinal tract.

14 Jun 2024

New armored CAR T cell therapy boosts response in Relapsed non-Hodgkin lymphoma patients

While CAR T cell therapy has revolutionized treatment for many blood cancers, including non-Hodgkin lymphoma (NHL), many patients who receive CAR T cell therapy do not experience a long-term remission.

13 Jun 2024

Open-ILD: Pioneering stem cell research to combat interstitial lung disease

Imagine a world where breathing is a luxury and a cough marks the sound of an inner battle. Interstitial Lung Disease (ILD), a condition characterised by inflammation and fibrosis, is a major cause of severe respiratory illness and can occur in children.

13 Jun 2024

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Human antibodies show promise against Black widow spider venom

There are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa.

12 Jun 2024

Enterprise Therapeutics publishes preclinical profile of ETD001, a novel inhaled ENaC blocker

Enterprise Therapeutics Ltd (Enterprise), a biopharmaceutical company dedicated to the discovery and development of novel therapies to improve the lives of people with respiratory diseases, today announced the publication of a peer reviewed study in the Journal of Cystic Fibrosis1.

12 Jun 2024