Fluorescence News and Research

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New imaging center opens at the University of California San Diego

The Nikon Imaging Center, a collaborative microscopy center that provides local researchers with access to the latest imaging technologies, opened September 13, 2018 at the University of California San Diego.

14 Sep 2018

Molecular switches are far more complex than previously assumed

The GTPases constitute a very large protein family, whose members are involved in the control of cell growth, transport of molecules, synthesis of other proteins, etc. Despite the many functions of the GTPases, they follow a common cyclic pattern.

10 Sep 2018

Individualized therapies targeting specific features show promise in transforming cancer treatment

Individualized therapies that target the specific genetic features of tumors have the potential to transform cancer diagnosis, treatment and care.

10 Sep 2018

Exeter’s new system can probe microscopic environments inside cells

A new system capable of probing microscopic environments inside cells has been installed at the University of Exeter's Bioimaging Centre.

7 Sep 2018

Researchers identify enzyme that plays vital role in sexual development of fungi

Biologists at Ruhr-Universität Bochum and Georg-August-Universität Göttingen have gained new insights into specific enzymes that effect the specialization of fungal cells.

5 Sep 2018

Improving neurosurgery for malignant brain tumors

Important research by Barrow Neurological Institute neurosurgeons and University of Washington (UW) scientists on novel imaging technology for malignant brain tumors was published in the August issue of the Nature journal, Scientific Reports.

4 Sep 2018

Image Cytometry Technology and Tissue Analysis

Image cytometry or tissue cytometry, not only measures the size, diameter and shape of a cell, but quantifies the molecular marker expression.

From TissueGnostics 4 Sep 2018

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers from Kanazawa University report in Journal of Neuroscience performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.

31 Aug 2018

Fluorescent protein sensor detects changes in cellular oxygen levels with very high sensitivity

Based on a protein from E. coli, scientists at Tokyo Institute of Technology have developed a fluorescent protein sensor able to provide real-time information on dynamic changes in oxygen levels with very high sensitivity.

30 Aug 2018

Small black box could change the way scientists search for new antibiotics

A small, black box developed in a McMaster University lab could change the way scientists search for new antibiotics.

30 Aug 2018

Researchers report how Zika proteins hijack host cells

Most people infected with Zika never show symptoms. But the virus sometimes causes severe disability -- from microcephaly in babies to weakness or partial paralysis in adults -- and there is no treatment.

28 Aug 2018

Scientists identify molecular pit crew responsible for refueling in signaling cells

During IndyCar races, pit stop crews will often refuel a car, replace wheels and complete minor repairs on a race car within 10 seconds. In this short time, a dozen or so people work rapidly and in a highly coordinated manner to complete a number of tasks with extraordinary efficiency.

24 Aug 2018

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

To successfully infect its host, the rabies virus must move from the nerve ending to the nerve cell body where it can replicate.

24 Aug 2018

New assay may help improve both sarcoma diagnosis and treatment

Sarcomas are rare tumors that are often misdiagnosed. Specific recurrent chromosomal rearrangements, known as translocations, can serve as essential diagnostic markers and are found in about 20 percent of sarcomas.

20 Aug 2018

Life Biosciences contributes $100,000 to fund its biomedical innovation course on aging

The MDI Biological Laboratory has announced that Life Biosciences, a biotech company co-founded by David Sinclair, Ph.D., a leading researcher on aging and age-related diseases, has contributed $100,000 to fund its biomedical innovation course on aging.

17 Aug 2018

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Drugs like crizotinib are used to treat patients with ROS1-positive lung cancer. But which patients are ROS1-positive? A University of Colorado Cancer Center study published in the Journal of Thoracic Oncology shows that common laboratory tests used to determine ROS1 status all have inherent limitations that can lead to false-negative results.

9 Aug 2018

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

Since the development of insulin to manage diabetes, pharmacists have longed to create an insulin pill. Past attempts have failed because insulin does not survive the harsh conditions of the gastro-intestinal system and cannot easily cross the GI wall.

9 Aug 2018

Compounds in 'monster' radish could potentially prevent heart disease and stroke

Step aside carrots, onions and broccoli. The newest heart-healthy vegetable could be a gigantic, record-setting radish. In a study appearing in ACS' Journal of Agricultural and Food Chemistry, scientists report that compounds found in the Sakurajima Daikon, or "monster," radish could help protect coronary blood vessels and potentially prevent heart disease and stroke.

9 Aug 2018

High Throughput Biophysical Screening for Development and Formulation of Biologics

In this interview, John Champagne, Ph.D. Senior Applications Scientist and Northeast Regional Manager for Wyatt Technology, talks to News-Medical about

From Waters | Wyatt Technology 1 Aug 2018

Turmeric derivative could be used in eye drops to treat early stages of glaucoma

A derivative of turmeric could be used in eye drops to treat the early stages of glaucoma, finds a new study led by UCL and Imperial College London researchers.

24 Jul 2018

Fluorescence News and Research

New imaging center opens at the University of California San Diego

Molecular switches are far more complex than previously assumed

Individualized therapies targeting specific features show promise in transforming cancer treatment

Exeter’s new system can probe microscopic environments inside cells

Researchers identify enzyme that plays vital role in sexual development of fungi

Improving neurosurgery for malignant brain tumors

Image Cytometry Technology and Tissue Analysis

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Fluorescent protein sensor detects changes in cellular oxygen levels with very high sensitivity

Small black box could change the way scientists search for new antibiotics

Researchers report how Zika proteins hijack host cells

Scientists identify molecular pit crew responsible for refueling in signaling cells

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

New assay may help improve both sarcoma diagnosis and treatment

Life Biosciences contributes $100,000 to fund its biomedical innovation course on aging

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Proof-of-concept technology using nanoparticles could offer new approach for oral medications

Compounds in 'monster' radish could potentially prevent heart disease and stroke

High Throughput Biophysical Screening for Development and Formulation of Biologics

Turmeric derivative could be used in eye drops to treat early stages of glaucoma

Industry Focus eBook - Fluorescence (1st edition) eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo