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Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

The study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and plaque formation in arteries.

27 Aug 2024

Children and adolescents experience unique long COVID symptoms

A study characterizes childhood long COVID, revealing distinct symptoms in children and adolescents, highlighting the need for tailored diagnostic approaches.

26 Aug 2024

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

Study identifies phenylacetylglutamine (PAGln), a gut microbiome metabolite, as a novel allosteric modulator of β2-adrenergic receptors, offering insights into its role in cardiovascular disease (CVD) risk.

26 Aug 2024

Strength training triggers key mechanisms for cellular waste clearance

The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs.

23 Aug 2024

Wake Forest Institute for Regenerative Medicine joins new NSF-funded pandemic prediction initiative

The Wake Forest Institute for Regenerative Medicine is proud to be part of a new initiative, supported by an $18 million grant from the U.S. National Science Foundation (NSF), aimed at enhancing global pandemic prediction and prevention capabilities.

23 Aug 2024

New technique enhances study of complex biological processes at the molecular level

A team of researchers led by Professor Sebastian Deindl at Uppsala University has developed a pioneering method that vastly improves the ability to observe and analyze complex biological processes at the single-molecule level.

23 Aug 2024

The impact of stem cells on the epigenetic clock

How old are you, really? Your chronological age is the number of years you have been alive. Your biological age is how old your cells are which scientists believe may better assess one's age-related health and disease risk. People biologically age at different rates, depending on genetic and environmental factors, so that a person's chronological age does not necessarily match their biological age. In recent years, direct-to-consumer biological age tests have become increasingly accessible and popular as interest has increased in this nascent science.

23 Aug 2024

Study sheds light on the dual nature of cellular senescence

Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells.

22 Aug 2024

Anti-obesity medication may help to prevent heart attacks and other major cardiac events

The anti-obesity medication semaglutide may help to prevent heart attacks and other major adverse cardiac events among overweight people who have cardiovascular disease, whether or not they also have heart failure, according to a new study led by UCL's Professor John Deanfield.

22 Aug 2024

New 3D imaging tool offers accurate assessment of metabolic health

Mayo Clinic researchers are using artificial intelligence (AI) with an advanced 3D body-volume scanner – originally developed for the clothing industry – to help doctors predict metabolic syndrome risk and severity.

22 Aug 2024

Robotic gait training improves mobility in patients with spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a rare X-linked neuromuscular disorder that results from an abnormal expansion of gene sequences in the androgen receptor gene.

22 Aug 2024

Study reveals long COVID's wide impact on children's health

The kids were correct all along. In the most comprehensive national study since the onset of the COVID-19 pandemic, a team of researchers that includes a Rutgers-organized consortium of pediatric sites has concluded that long COVID symptoms in children are tangible, pervasive, wide ranging and clinically distinct within specific age groups.

22 Aug 2024

Python's remarkable physiology could lead to new medical breakthroughs

Researchers fed pythons who had fasted for 28 days a meal of 25% of their body weight and compared them to snakes who had not been fed.

22 Aug 2024

The role of soy in improving metabolic health

Pennington Biomedical Research Center's Dr. Candida Rebello wants to know more about the intersection of blood sugar levels and a diet rich in soy. This intersection is the primary focus of her new study, "Lifestyle Intervention for Improving Metabolic and Motivational Outcomes," or MOTIVATE, which explores how specific diets can impact blood sugar, and potentially improve mood and energy levels.

22 Aug 2024

Study reveals distinct long COVID patterns in children and adolescents

Scientists investigating long COVID in youth found similar but distinguishable patterns between school-age children (ages 6-11 years) and adolescents (ages 12-17 years) and identified their most common symptoms.

21 Aug 2024

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

A new study from researchers with UCLA Health and collaborating organizations has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

21 Aug 2024

New index identifies school-age children likely to have long COVID

A research team led by the National Institutes of Health's RECOVER Initiative and supported by its Clinical Science Core (CSC) at NYU Langone Health, has designed a new way to identify which school-age children and adolescents most likely have Long COVID.

21 Aug 2024