Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Mesothelial cells enable rapid invasion and spread of ovarian cancer

Ovarian cancer kills more women than any other gynecological cancer. Most patients receive their diagnosis only after the disease spreads throughout the abdomen.

7 Feb 2026

Cholesterol transporter ABCA1 boosts macrophage-driven cancer immunity

In recent years, cancer researchers have made major breakthroughs by using the body's immune system to fight cancer. One of the most promising approaches, known as immune checkpoint blockade, works by releasing molecular "brakes" on T cells.

7 Feb 2026

Tumor-targeted chimeric drug increases efficacy and limits side effects

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more effectively.

7 Feb 2026

Water pressure mechanism enables fast amoeboid cancer cell movement

Cancer is one of the leading causes of death worldwide, marked by the uncontrolled growth of abnormal cells.

7 Feb 2026

Binghamton University receives $2.5 million to develop a next-generation avian flu vaccine

Outbreaks of avian flu at U.S. poultry farms led to more than $1.5 billion in losses over the last two years and drove egg prices to all-time highs in 2025.

6 Feb 2026

Mycoprotein demonstrates strong potential for sustainable nutrition

Plant-based food as an alternative to meat is high on the agenda today, and mycoprotein (fungal protein) in particular has come into focus in recent years.

6 Feb 2026

Blocking p300 restores chemotherapy sensitivity in resistant tumors

Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers.

6 Feb 2026

Building flexible governance for biological data powering AI systems

In a Policy Forum, Doni Bloomfield and colleagues discuss the need for expanded – yet tailored and flexible – governance for the biological data used to develop powerful artificial intelligence (AI) models.

6 Feb 2026

Senescent neutrophils promote tumor survival across cancer types

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

New DNA-based vaccine scaffolds boost targeted immune responses to HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Investigational anti-clotting drug reduces risk of second ischemic stroke without bleeding concerns

An investigational anti-clotting medication, asundexian, demonstrated a reduction in the risk of a second ischemic (clot-caused) stroke without raising bleeding concerns, according to a preliminary late-breaking science presentation at the American Stroke Association's International Stroke Conference 2026.

6 Feb 2026

Triple negative breast cancer cells use new strategy to boost metastatic ability

Researchers at Baylor College of Medicine have uncovered a strategy that triple negative breast cancer (TNBC) cells use to boost their ability to metastasize, or spread to other organs.

6 Feb 2026

New workflow boosts nuclear delivery for safer gene therapy

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus.

5 Feb 2026

Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein

Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future therapies.

5 Feb 2026

Inhibiting PTP1B protein improves memory in Alzheimer’s disease models

Alzheimer's disease is often measured in statistics: millions affected worldwide, cases rising sharply, costs climbing into the trillions.

5 Feb 2026

Liver-derived protein supports bone health in males

New research suggests the liver plays a previously unrecognized role in bone health, but only in males.

5 Feb 2026

Five mutation patterns shape how cancers evade immunity

Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the immune system, while others help cancers hide.

4 Feb 2026

Pigs and grizzly bears may reveal secrets of youthful skin

The secret to youthful appearance and repairing scars may lie in a microscopic skin structure humans share with pigs and grizzly bears - but, surprisingly, not monkeys.

4 Feb 2026

Hormone therapy reduces abnormal nerve growth in chronic back pain

Low back pain (LBP) is one of the most common health problems worldwide, affecting people of all ages and placing a heavy burden on healthcare systems. Many patients experience persistent discomfort that interferes with work, sleep, and daily activities.

4 Feb 2026

Small molecule targets glioblastoma oncogene in preclinical studies

UVA Comprehensive Cancer Center scientists have identified a molecule that blocks the gene responsible for glioblastoma, raising hopes that the molecule could become a much-needed new treatment for the deadliest brain cancer.

4 Feb 2026