Physiology News and Research

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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.

Researchers identify genes that become active when carotid plaque rupture leads to a stroke

Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that become active in carotid arteries when plaque rupture causes a stroke.

11 Aug 2022

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Melanopsin (OPN4) is a light-sensing protein found in skin and retina cells. A new study conducted at the University of São Paulo (USP) in Brazil suggests that OPN4 can also participate in the development and progression of melanoma, the most aggressive type of skin cancer.

10 Aug 2022

Research paves the way for therapies to treat or delay preterm labor

Researchers have identified a cause of preterm labor, an enigma that has long challenged researchers. New research published in The Journal of Physiology suggests a protein, called Piezo1, is responsible for regulating the behavior of the uterus.

9 Aug 2022

Research projects the future mortality burden due to hot nights

Excessively hot nights caused by climate change are predicted to increase the mortality rate around the world by up to 60% by the end of the century, according to a new international study that features research from the UNC Gillings School of Global Public Health.

9 Aug 2022

Children are less fit and more obese than ever before, study says

Record levels of obesity and physical inactivity among children mean they are set to bear the brunt of poorer health effects from rising global temperatures – that's the stark warning in a new comprehensive review of current studies on the topic.

5 Aug 2022

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

5 Aug 2022

Study reveals details about the complicated visual network forms in mice

A new study in mice has revealed never-before-seen details about how the complicated visual network forms in them. This research could inform future research into the treatment of congenital blindness. But given the parallels between biological neural tissue and digital artificial intelligence, this research could also help software engineers develop better and more general-purpose artificial intelligences.

5 Aug 2022

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth.

4 Aug 2022

Exposure to air pollutants released during wildfires has ill effects among children

New research linking air pollution data from federal monitors in the Sacramento area of California, including during significant fires, is showing ill effects of pollution exposure among children, a new University of California, Davis, study suggests.

4 Aug 2022

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety of chronic human ailments, including obesity, type 2 diabetes, atherosclerosis, cancer, non-alcoholic fatty liver disease and inflammatory bowel disease.

4 Aug 2022

Designing an app to diagnose ALS

In this interview, we speak to Dr. Jordan Green about his latest research partnership with Modality.AI that investigated whether an app could be used to effectively diagnose speech decline due to ALS.

4 Aug 2022

Researchers unravel mechanism of action of bacterial Tc toxin in fatal attacks

A harmful and often deadly substance made by bacteria, a bacterial toxin manipulates host cell functions and disrupts vital cell processes in a living organism.

3 Aug 2022

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

In this interview, we speak to Tom Kostrzewski, VP of Science and Technology at CN Bio, about their organ-on-a-chip product and the future of drug discovery.

From CN Bio 3 Aug 2022

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Disease of the microscopic blood vessels that feed the white matter of our brain is associated with worse cognitive function and memory deficits in individuals with Alzheimer's, scientists report.

2 Aug 2022

Twin mothers are not actually more fertile than other women, study finds

Twin births aren't exactly common. In humans, they occur in one to three per cent of all births.

2 Aug 2022

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Using an innovative microscopy method, scientists at The Picower Institute for Learning and Memory at MIT observed how newborn neurons struggle to reach their proper places in advanced human brain tissue models of Rett syndrome, producing new insight into how developmental deficits observed in the brains of patients with the devastating disorder may emerge.

29 Jul 2022

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

While infants exposed to opioids during their mother's pregnancy have been linked to adverse health outcomes, a new study at the University of Missouri has found prenatal opioid exposure could trigger long-term neurological or behavioral effects later in a child's life.

29 Jul 2022

'Western style' diet high in fat and sugar can negatively affect breast milk and baby's health

A diet high in sugar and fat such as burgers, fries and fizzy drinks can negatively affect a new mother's breast milk and baby's health even before the child is conceived.

27 Jul 2022

Physiology News and Research

Researchers identify genes that become active when carotid plaque rupture leads to a stroke

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Study evaluates the tumor-modulatory effects of opsins on melanoma cancer

Research paves the way for therapies to treat or delay preterm labor

Research projects the future mortality burden due to hot nights

Children are less fit and more obese than ever before, study says

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

Study reveals details about the complicated visual network forms in mice

Researchers discover two signaling pathways that are downregulated in human hearts after birth

Exposure to air pollutants released during wildfires has ill effects among children

Using native microbes as chassis for transgene delivery in live bacterial therapeutics

Designing an app to diagnose ALS

Researchers unravel mechanism of action of bacterial Tc toxin in fatal attacks

Turning to Organ-on-a-Chip Studies for the Future of Drug Discovery

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Twin mothers are not actually more fertile than other women, study finds

Innovative microscopy method reveals how neurons struggle to reach their destination in Rett syndrome models

Prenatal opioid exposure may cause long-term neurological or behavioral effects later in a child's life

'Western style' diet high in fat and sugar can negatively affect breast milk and baby's health

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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