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New antibiotic-resistant bacteria strain may be spreading across Asia

A virulent new strain of antibiotic-resistant bacteria that causes severe disease could be spreading widely across Asia - posing significant challenges to global public health, a new study reveals.

7 Nov 2024

Stanford researchers unveil the key role of extrachromosomal DNA in cancer

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles - until recently dismissed as inconsequential - are major drivers of many types of human cancers.

6 Nov 2024

Researchers uncover immune mechanism behind myocarditis from cancer immunotherapy

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

6 Nov 2024

New research uncovers 16 genes that aid breast cancer survival

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they've escaped the low-oxygen regions of a tumor.

5 Nov 2024

No evidence Trump’s drug program for terminal patients saved ‘thousands’ of lives

Former President Donald Trump has boasted in recent months about "Right To Try," a law he signed in 2018. It's aimed at boosting terminally ill patients' access to potentially lifesaving medications not yet approved by the Food and Drug Administration.

5 Nov 2024

Lupus Research Alliance announces 33 studies to be presented at ACR Convergence 2024

The Lupus Research Alliance (LRA), the largest private funder of lupus research worldwide, today announced that a total of 33 studies, funded by the organization or supported by its clinical research affiliate Lupus Therapeutics, will be presented at ACR Convergence 2024.

5 Nov 2024

Johns Hopkins study offers new hope for wet AMD patients

A new study from researchers at Wilmer Eye Institute, Johns Hopkins Medicine explains not only why some patients with wet age-related macular degeneration (or "wet" AMD) fail to have vision improvement with treatment, but also how an experimental drug could be used with existing wet AMD treatments to save vision.

4 Nov 2024

$1 million grant supports research on groundbreaking therapies for MS

Multiple sclerosis (MS) is a debilitating disease of the brain and spinal cord that impacts millions worldwide.

4 Nov 2024

Researchers develop the first polymer-based therapeutic for Huntington’s disease

Breakthrough polymer-based therapy shows promise in reversing Huntington's disease symptoms by preventing toxic protein clumps and enhancing neuronal survival.

4 Nov 2024

SpaceX CRS-31 supports heart health, neurodegeneration, and student science

More than 25 payloads sponsored by the International Space Station (ISSInternational Space Station) National Laboratory, including technology demonstrations, in-space manufacturing, student experiments, and multiple projects funded by the U.S. National Science Foundation (NSF), are bound for the orbiting outpost.

4 Nov 2024

Huntington’s disease symptoms reduced by new peptide-polymer therapy

Scientists at Northwestern and Case Western Reserve universities have developed the first polymer-based therapeutic for Huntington's disease, an incurable, debilitating illness that causes nerve cells to break down in the brain.

3 Nov 2024

Researchers achieve accurate EV analysis to detect brain disease

Brain disorders like Parkinson's (PD) or Alzheimer's Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages.

3 Nov 2024

Study links brain proteins to individual differences in functional connectivity

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale.

1 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

VALANX Biotech and Fina Biosolutions Introduce ClickCRM for Rapid Conjugate Vaccine Development

VALANX Biotech (VALANX), a biotech company developing novel technology for site-specific protein conjugation in drug and diagnostics discovery, and Fina Biosolutions LLC (FinaBio), experts in conjugate vaccine development and conjugate chemistry, today announced the signing of a joint IP and licensing agreement.

From VALANX Biotech 31 Oct 2024

Study challenges early intervention for asymptomatic aortic stenosis

The EVOLVED trial found that early aortic valve intervention in patients with asymptomatic severe aortic stenosis (AS) and mid-wall myocardial fibrosis on magnetic resonance imaging did not reduce the incidence of the composite primary endpoint of all-cause death or unplanned aortic stenosis hospitalization compared with guideline-directed conservative management.

30 Oct 2024

Machine learning reveals secrets of aging in flies and humans

Discoveries that impact lifespan and healthspan in fruit flies are usually tested in mice before being considered potentially relevant in humans, a process that is expensive and time intensive. A pioneering approach taken at the Buck Institute leapfrogs over that standard methodology.

30 Oct 2024

Cardiac damage framework may identify patients who could benefit from earlier TAVR

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

29 Oct 2024

Discovery of multidomain enzyme enhances drug development potential

Pharmaceutical scientists from the National University of Singapore (NUS) have identified and characterized a unique multidomain enzyme capable of catalyzing two distinct types of reactions, both vital for making drug molecules.

29 Oct 2024

Researchers develop new approach to predict immunotherapy response in breast cancer patients

Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy.

29 Oct 2024