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Tumor collagen structure may help explain racial disparities in cancer outcomes

In cancer care, accurate tools for predicting whether a tumor will spread (metastasize) can help patients receive the most appropriate treatments.

15 Jun 2025

Researchers identify cellular hotspots that trigger ferroptosis

Researchers at the VIB-KU Leuven Center for Cancer Biology have uncovered how a unique interaction between two cellular compartments, namely the endoplasmic reticulum (ER) and mitochondria, can act as a central ignition point for ferroptosis, a form of cell death driven by lipid oxidation and iron.

14 Jun 2025

Understanding the role of astrocytes in depression and neuroinflammation

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness.

13 Jun 2025

Advancing precision oncology in intrahepatic cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Boosting CAR T cell survival to improve solid tumor therapy

Chimeric Antigen Receptor (CAR)-T cells are a promising cancer therapy that are made from the patient's own T cells, which are reprogrammed to fight their cancer. One of the limitations of CAR-T cell therapy is the ability of these cells to survive long enough to target the entire tumor.

13 Jun 2025

Rare ovarian tumor found during postmenopausal surgery for pelvic organ prolapse

A new case report was published in Volume 12 of Oncoscience on May 22, 2025, titled "A rare case: Pure Sertoli cell tumor uncovered in atrophic ovary during postmenopausal vault prolapse evaluation."

13 Jun 2025

Mapping genetic activity offers new clues for personalized cancer treatment

City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, co-led the first study to demonstrate that characterizing genetic material near chromosomes forecasts how mutated, cancer-causing genes reengineer DNA and alter the tumor microenvironment.

13 Jun 2025

Short peptides show promise in blocking breast cancer metastasis

A surgeon can excise breast cancer from the body, but even the most skilled scalpel may not be able to remove every cell - especially when the cells have spread from the original disease site elsewhere in the body.

13 Jun 2025

Low-dose vitamin D supplements can increase effectiveness of chemotherapy in breast cancer patients

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer.

13 Jun 2025

AI and film animation tools lead to breakthrough in coronavirus drug discovery

About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases, to epidemic and even pandemic outbreaks, as we experienced with the COVID-19 pandemic.

13 Jun 2025

Updated EU CAR-T Handbook offers insights into latest developments in CAR-T cell therapies

The EBMT, the EHA, and the GoCART Coalition proudly announce the release of the second edition of the EU CAR-T Handbook, a comprehensive, open-access resource covering the latest developments in CAR-T cell therapies.

12 Jun 2025

Engineered lymph node model advances human immune system research

Scientists with the Fralin Biomedical Research Institute at VTC have created an engineered model of the supportive tissue found within a lymph node to study human health.

12 Jun 2025

TTUHSC researchers seek to understand TBX2's role in bone metastasis of prostate cancer

The American Cancer Society estimates that more than 313,780 cases of prostate cancer will be diagnosed in the United States in 2025, resulting in approximately 35,770 deaths.

12 Jun 2025

Cholesterol shields cancer cells from heat treatment in hyperthermia therapy

Hyperthermia, a cancer treatment using controlled heat to kill tumor cells, shows promise but faces limitations due to some tumor cells' unexpected heat resistance.

12 Jun 2025

Telehealth-based care program boosts function and mood in seniors with cancer

New research in the June 2025 issue of JNCCN-Journal of the National Comprehensive Cancer Network found that older people with cancer had better daily functioning, improved mood, stronger illness understanding, and a higher quality of life if they participated in a telehealth-based care program called Geriatric Assessment-Guided Intervention-Supportive Care (GAIN-S).

12 Jun 2025

Long term use of desogestrel linked to small increase in brain tumor risk

Taking the progestogen-only contraceptive pill desogestrel continuously for more than five years is associated with a small increased risk of developing a type of brain tumor called an intracranial meningioma, finds a study from France published by The BMJ today.

12 Jun 2025