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RION engages Lonza to scale manufacturing exosome based therapeutics

RION, a commercial and clinical-stage regenerative medicine company pioneering platelet-derived exosomes for both human and animal health applications, has announced a collaboration with Lonza, one of the world’s largest contract development and manufacturing organizations (CDMOs), to provide cGMP manufacturing and technical support for commercial scale production of its Purified Exosome Product™ (PEP™) drug substance for late phase clinical supply and beyond.

From Lonza 26 Sep 2025

Healthy habits linked to younger brain age

Your chronological age may say 65, but your brain could be acting a decade younger - or older - depending on your life experiences.

25 Sep 2025

Lifespan study reveals age-specific biological changes in Down Syndrome

In a groundbreaking new study published in Nature Communications, researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of Colorado Anschutz discovered important differences in the physiological changes observed in over 300 individuals with Down syndrome across the lifespan.

24 Sep 2025

Tai chi improves memory and sleep in older adults with type 2 diabetes

A 12-week randomized trial found that remotely delivered Tai Chi significantly enhanced cognitive performance and sleep quality in older adults with Type 2 Diabetes. These gains surpassed those from supervised fitness walking or usual care, without increasing adverse events.

17 Sep 2025

Artificial intelligence transforms lumbar spine modeling for faster patient care

Nearly 3 in 10 adults in the United States have experienced lower back pain in any three-month period, making it the most common musculoskeletal pain.

17 Sep 2025

Population aging identified as largest contributor to the increasing burden of musculoskeletal disorders

Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.

16 Sep 2025

GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide.

16 Sep 2025

Healthy diet found to reduce chronic pain beyond weight loss

We all know the benefits of a healthy diet. But new research from the University of South Australia shows that eating nutritious food is about far more than ticking off the five food groups – it can also significantly reduce chronic pain.

9 Sep 2025

Piezo1 identified as key trigger for tension driven skin expansion

Investigators at Johns Hopkins Medicine report new evidence that the protein Piezo1 controls skin growth by detecting when skin is stretched and then coordinating the metabolic and immune changes necessary for growth.

5 Sep 2025

Wireless ultrasound shows promise for faster injury assessment in athletes

Many student-athletes are preparing or returning to the field or court for their upcoming season. With the start of both collegiate and professional sports, injuries are inevitable - and when they do happen, getting fast, reliable results can make all the difference.

4 Sep 2025

Daily walking reduces risk of chronic lower back pain

A major study has investigated the relationship between walking and the risk of developing chronic lower back problems.

4 Sep 2025

Why repetitive wrist use in esports could lead to long-term injuries

The study highlights wrist extensor fatigue in esports, emphasizing the role of game genre and the need for preventive measures to combat musculoskeletal risks.

4 Sep 2025

People live longer worldwide but not necessarily healthier, study finds

Researchers mapped the global healthspan-lifespan gap across 183 countries, showing people live longer but not healthier, with Africa experiencing the fastest widening gap. Distinct disease-burden clusters explain regional differences and highlight the need for region-specific health strategies.

2 Sep 2025

PEPITEM shows promise in treating osteoporosis by enhancing bone health

Researchers from the University of Birmingham, U.K., have identified bioactive peptide sequences in PEPITEM molecule, and demonstrated the biological of activity of the full PEPITEM molecule in counteracting key changes caused by osteoporosis.

2 Sep 2025

New core dataset advances standardized care and research in systemic lupus erythematosus

The European Alliance of Associations for Rheumatology - has published new recommendations on core datasets to be used in systemic lupus erythematosus (SLE).

22 Aug 2025

Landmark robotic spine surgery advances pediatric orthopedic care at Ochsner Children’s

Ochsner Children's has achieved a major milestone by performing the first robotic-assisted pediatric spine deformity surgery in Louisiana and the Gulf South.

18 Aug 2025

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.

13 Aug 2025

Australian study finds lasting relief for back pain through cognitive functional therapy

Australian research has shown that a personalized program that helps people with chronic, disabling low back pain better understand their condition and take charge of its management produces large benefits that are sustained over three years.

5 Aug 2025

HIV trial points to semaglutide as a new anti-aging contender

Once-weekly semaglutide significantly slowed epigenetic aging in adults with HIV-associated lipohypertrophy, as measured by multiple DNA methylation clocks in a randomized controlled trial. These exploratory findings suggest GLP-1 receptor agonists could impact biological aging but require further validation in broader populations.

4 Aug 2025

Flooding linked to increased hospitalizations among older adults

New research examining 17 years of data from Medicare hospitalization claims and major flooding events finds increased rates of skin diseases, nervous system diseases, and injuries or poisonings among adults aged 65 and older following major floods.

31 Jul 2025