Radiotherapy News and Research

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Radiation therapy (in North America), or radiotherapy (in the UK and Australia) also called radiation oncology, and sometimes abbreviated to XRT, is the medical use of ionizing radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis).

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

A new study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC) demonstrates that monitoring circulating tumor DNA (ctDNA) can refine and personalize the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

9 Sep 2025

HypoRT with concurrent chemotherapy reduces treatment time and toxicity for patients with LS-SCLC

A multi-center, randomized phase III trial has found that a three-week hypofractionated radiotherapy (HypoRT) schedule with concurrent chemotherapy provides similar survival outcomes and reduced toxicity compared to the standard six-week conventional fractionated radiotherapy (ConvRT) schedule for patients with limited-stage small cell lung cancer (LS-SCLC).

8 Sep 2025

Study urges significant investment in cancer research in poorer nations

Researchers at the University of Southampton, examining worldwide variations in funding for cancer research, say there's a pressing need to invest more in lower-income countries.

2 Sep 2025

Androgen deprivation therapy lowers satisfaction after penile prosthesis surgery

Prostate cancer is the most common malignancy among men, with over 160,000 new cases diagnosed annually in the United States.

1 Sep 2025

Study finds minimal risk of second cancer in breast cancer survivors

For women diagnosed with early breast cancer, the long-term risk of developing a second primary cancer is low (around 2-3% greater than women in the general population), finds a study published by The BMJ today.

28 Aug 2025

Insights into the clinical presentation and management of sellar chondrosarcomas

Chondrosarcomas are a malignant form of bone cancer that is composed of cartilage-forming tumor cells. Sellar chondrosarcomas, which occur in the sellar region at the base of the skull, are a very rare manifestation of chondrosarcoma, making up only around 0.2% of all tumors found in the skull.

22 Aug 2025

Blocking brain damage may slow aggressive glioblastoma growth

Blocking brain damage triggered by a glioblastoma, an aggressive brain cancer, may slow the growth of the cancer and allow the brain to keep working better for longer, according to a new study led by UCL (University College London) researchers.

20 Aug 2025

Advancing cancer treatment with targeted microrobotic swarms

Cancer remains one of the most challenging diseases to treat, as conventional therapies like chemotherapy and radiotherapy are often hindered by poor specificity, systemic toxicity, and damage to healthy tissues.

18 Aug 2025

PSMA PET/CT improves outcomes for men with recurrent prostate cancer

A new study from Denmark shows for the first time that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have improved survival rates compared to those who do not.

14 Aug 2025

Early-onset pancreatic cancer patients benefit more from neoadjuvant chemotherapy and surgery

The incidence of early-onset pancreatic cancer (EOPC) is rising, yet optimal treatment strategies remain unclear.

7 Aug 2025

Bacteria-based cancer therapy achieves tumor eradication without immune cells

A joint research team led by Professor Eijiro Miyako of the Japan Advanced Institute of Science and Technology (JAIST), in collaboration with Daiichi Sankyo Co., Ltd. and University of Tsukuba, has developed a groundbreaking immune-independent bacterial cancer therapy using a novel microbial consortium called AUN.

5 Aug 2025

ChatGPT helps speed up patient screening for clinical trials

A new study in the academic journal Machine Learning: Health discovers that ChatGPT can accelerate patient screening for clinical trials, showing promise in reducing delays and improving trial success rates.

1 Aug 2025

T cell senescence shapes cancer prognosis and immunotherapy response

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by tumor-associated antigens, metabolic pathway alterations, activation of chronic inflammatory responses, proliferation of immunosuppressive cells, and T cell damage caused by tumor radiotherapy and chemotherapy.

31 Jul 2025

Machine learning model predicts radiotherapy response in patients with nasopharyngeal carcinoma

Researchers in China have developed a powerful machine learning model that can help determine which patients with nasopharyngeal carcinoma (NPC) are likely to respond well to radiotherapy-a common treatment for this type of cancer.

30 Jul 2025

Synergistic effects of radiation and immunotherapy boost anti-tumor immunity

Head and neck squamous cell carcinomas (HNSCC) are a group of cancers that affect cells in and around our mouth and nose.

29 Jul 2025

Innovative immunotherapy trial opens for newly-diagnosed glioblastoma patients

A UCL-sponsored clinical trial for patients newly diagnosed with glioblastoma, an aggressive form of brain cancer, has opened at UCLH's National Hospital for Neurology and Neurosurgery and Clinical Research Facility, in memory of Baroness Margaret McDonagh.

24 Jul 2025

Radiation primes the immune system to attack lung tumors resistant to immunotherapy

By sparking the immune system into action, radiation therapy makes certain tumors that resist immunotherapy susceptible to the treatment, leading to positive outcomes for patients, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Netherlands Cancer Institute.

22 Jul 2025

Research unravels the immune secrets of a cured pediatric rhabdoid tumor

Although relatively rare, many childhood cancers remain life-threatening and lack effective personalized treatments. Rhabdoid tumors are among these fatal cancers and can develop in various tissues and organs.

16 Jul 2025

Pathogenic mechanisms of Fusobacterium nucleatum in colorectal cancer and emerging therapies

In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, Fusobacterium nucleatum (Fn) has been identified as a critical pathogenic factor in CRC.

12 Jul 2025

New model can accurately predict lung motion during breathing

A research team led by Prof. LI Hai from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has developed a new model that can accurately predict lung motion caused by breathing, offering safer and more precise options for lung biopsies and radiotherapy.

10 Jul 2025