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Trained immunity may exacerbate inflammatory bone loss disorders

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop therapies to treat or prevent diseases from influenza to autoimmune disease and cancer.

27 Feb 2025

Scientists pioneer fecal transplant capsules to enhance pancreatic cancer treatment

Scientists at Lawson Research Institute (Lawson) of St. Joseph's Health Care London and London Health Sciences Centre Research Institute (LHSCRI) are the first in the world to study fecal transplants using capsules containing microbes from the gut of healthy volunteers to improve the response of patients with advanced pancreatic cancer to chemotherapy.

26 Feb 2025

Venom is everywhere: Study examines hidden toxin delivery systems across life forms

Forget snakes and spiders—a new review details venomous plants, fungi, and even bacteria, proving that nature's deadliest secret weapon is more widespread than we ever imagined.

23 Feb 2025

Your home is full of mold, but daycares are teeming with yeast—here’s why

Researchers found that daycares have a higher abundance of yeasts, while private houses contain more spore-producing molds, with occupant density and ventilation playing key roles in fungal distribution.

23 Feb 2025

LUC7 proteins play crucial role in efficient RNA splicing

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

Fungal component may protect against flu-related lung damage

A component found in all fungi may provide a shield against flu-related lung damage, according to a new study.

18 Feb 2025

Study highlights the need for more diversity in vaginal microbiome research

This study emphasizes the need for global equity in vaginal microbiome research, addressing health disparities and improving female health strategies worldwide.

14 Feb 2025

Replacing meat with plant-based alternatives reduces cholesterol and weight

A study led by a researcher from the University of Granada and carried out in collaboration with the University of Castilla-La Mancha and the Francisco de Vitoria University has shown that replacing meat consumption with plant-based alternatives that simulate meat products would reduce total cholesterol (6%), LDL cholesterol (12%) and even body weight (1%) in the short term (1 to 8 weeks).

28 Jan 2025

Researchers reveal the role of texture and taste in shifting to a planet-friendly diet

Understanding the science behind meaty tastes and textures could be the key for more people switch to a planet-friendly plant diet, researchers suggest.

27 Jan 2025

Study reveals how gut bacteria influence immune cell training and inflammation

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes-modifications that alter gene activity without affecting DNA sequence-in the stem cells that give rise to immune cells.

22 Jan 2025

How gut microbiota impacts childhood obesity

Gut microbiota plays a critical role in childhood obesity by influencing energy metabolism, inflammation, and appetite regulation, with emerging therapeutic strategies like probiotics, dietary interventions, and fecal microbiota transplantation showing promise.

21 Jan 2025

Researchers utilize mosquito mating to spread malaria-fighting fungi

Researchers have developed genetically modified fungi that can kill malaria-transmitting mosquitoes through sexual transmission, offering a promising solution to target both indoor and outdoor populations.

19 Jan 2025

The diverse immunological functions of megakaryocytes

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

17 Jan 2025

New study links cervicovaginal microbiome to increased risk of Chlamydia infections

The cervicovaginal microbiome's role in Chlamydia infections underscores the need for molecular classification to enhance prevention and treatment strategies.

17 Jan 2025

Oil-based solution enables room temperature storage of protein therapeutics

A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold. The discovery, led by researchers at Penn State, could eliminate the need for refrigeration for hundreds of life-saving medicines like insulin, monoclonal antibodies and viral vaccines.

17 Jan 2025

Plant chemical discovered to prevent biofilm formation

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

10 Jan 2025

Carrots may offer natural support for people with type 2 diabetes

Could an ordinary carrot improve the treatment of type 2 diabetes? A new study from SDU suggests so.

8 Jan 2025

Psilocybin shows potential for treating mental health disorders in people with cancer and addiction

One or two doses of psilocybin, a compound found in psychedelic mushrooms, may improve the mental health of cancer patients when accompanied by psychotherapy, a new report suggests.

2 Jan 2025

Solving a decades-long puzzle in leishmaniasis drug development

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 people around the world every year.

20 Dec 2024

Nasal fungi differ in people with allergies and asthma

This study identifies key differences in nasal fungi composition in asthma and allergy patients, offering insights into their role in airway disease dynamics.

19 Dec 2024