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Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Epigenetic scores offer new insights into cardiometabolic disease prevention

A new study explores how epigenetic markers-chemical modifications that influence gene activity-can help predict the risk of developing cardiometabolic diseases and guide personalized prevention strategies.

25 Mar 2025

The best diet for aging well, backed by a 30-year study of 100,000 people

A 30-year study of over 100,000 U.S. adults found that consistent adherence to healthy dietary patterns, especially the AHEI, was strongly linked to successful aging. Diets rich in plant-based foods and healthy fats, with some low-fat animal products, improved physical, mental, and cognitive health.

25 Mar 2025

New open-source tool identifies aging cells to help fight chronic diseases

For human health, prematurely aging cells are a big problem. When a cell ages and stops growing, its function changes, which can cause or worsen cardiovascular disease, Alzheimer's disease and other chronic diseases.

25 Mar 2025

Blocking an inflammatory receptor in the retinas of aging mice improves retinal health

A new research paper was published in Aging (Aging-US) on January 31, 2025, in Volume 17, Issue 2, titled "Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice."

25 Mar 2025

New brain metabolism model reveals key targets for reversing aging

The most comprehensive model of the brain’s metabolism, incorporating more than 16,800 biochemical interactions, has identified key targets to reverse the age-related decline in brain function.

25 Mar 2025

Increased mobility linked to lower risk of hospitalization in heart failure patients

Compared with those who spent most of their time in a single room, people with heart failure with preserved ejection fraction (HFpEF) who were able to travel outside of their home without assistance were significantly less likely to be hospitalized or die within a year, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

25 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Ketogenic diet reverses obesity-linked biological aging by over 6 years

Obesity speeds up biological aging at the molecular level, but this study finds that a very-low-calorie ketogenic diet (VLCKD) can significantly reverse this effect.

24 Mar 2025

Red wine lowers bad cholesterol but doesn’t improve overall heart health

Moderate red wine consumption is linked to a small but significant reduction in LDL cholesterol, according to a systematic review and meta-analysis of 33 studies. However, the study found no consistent effects on HDL, triglycerides, total cholesterol, or fibrinogen.

24 Mar 2025

What do Blue Zone diets have in common? Polyphenols that may slow aging

Scientists reviewed how polyphenol-rich diets in Blue Zones may help people live longer, healthier lives by targeting biological hallmarks of aging. They call for more research to measure polyphenol intake and test its effects on human longevity.

24 Mar 2025

Skipping exercise? Just sitting less may still improve your metabolic health

Older adults who limit their sedentary time have lower metabolic syndrome risk, regardless of how active they are or how healthy they eat. Even light movement can support better metabolic health when replacing prolonged sitting.

24 Mar 2025

Sticking to Life’s Essential 8 slashes cancer risk, major study shows

Long-term adherence to the American Heart Association’s “Life’s Essential 8” lifestyle score significantly reduces the risk of overall and site-specific cancers. Stable high LE8 scores over four years were linked to notably lower risks of lung, breast, liver, and colorectal cancers in a large Chinese cohort study.

23 Mar 2025

Aquablation shows promise for treating enlarged prostate with fewer side effects

Using a high-pressure water jet to operate on an enlarged prostate can better preserve the ability to ejaculate, compared with standard laser surgery, finds research.

22 Mar 2025

Research reveals how dendrites connect memories in the brain

If you've ever noticed how memories from the same day seem connected while events from weeks apart feel separate, a new study reveals the reason: Our brains physically link memories that occur close in time not in the cell bodies of neurons, but rather in their spiny extensions called dendrites.

22 Mar 2025

Targeting brain’s waste removal system may help combat cognitive decline

As aging bodies decline, the brain loses the ability to cleanse itself of waste, a scenario that scientists think could be contributing to neurodegenerative conditions such as Alzheimer's disease and Parkinson's disease, among others.

21 Mar 2025

Study offers new insights into the harmful effects of sugar-sweetened beverages on human health

Researchers at the Advanced Research Unit on Metabolism, Development & Aging (ARUMDA), in the Tata Institute of Fundamental Research (TIFR, Mumbai and TIFR Hyderabad), have unveiled a comprehensive understanding of the harmful effects of sugar-sweetened beverages (SSBs) on human health, using a preclinical mouse model that closely mimics human consumption patterns.

21 Mar 2025