Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

UCLA study identifies lipid imbalance as pulmonary fibrosis trigger

A new UCLA Health study in mice has identified a new potential trigger for pulmonary fibrosis: lipid dysregulation (a fat imbalance) within alveolar macrophages.

9 Nov 2026

Could a daily supplement keep blood vessels healthier as we age?

The study highlights a multi-compound nutritional supplement's potential to improve blood vessel function and lower blood pressure, aiding vascular health.

9 Nov 2026

Cleaner bedroom air linked to improved blood sugar control

Using portable filters to reduce exposure to air pollution during sleep may stabilize the large spikes in blood sugar experienced by people with prediabetes, a condition in which sugar (glucose) levels are higher than normal, a new study shows.

8 Nov 2026

Early heart procedures do not improve long-term survival in stable heart disease

Patients with stable heart disease and abnormal stress tests who have invasive procedures early in their care do not live longer than those initially treated with drugs and lifestyle changes alone, an international study shows.

8 Nov 2026

ZEUS trial challenges assumptions about targeting inflammation in heart disease

Like cholesterol, inflammation causally contributes to the risk of cardiovascular disease, but findings from the clinical trial ZEUS indicate that the road to targeting inflammation may be less straightforward than once thought.

8 Nov 2026

Hidden genetic differences in gut bacteria may hold clues to aging

Researchers analyzed approximately 12.8 million gut microbial genetic variants in 10,781 individuals across six cohorts, identifying 940 independent associations with 69 human health characteristics and environmental exposures. Nearly two-thirds of these associations were not accompanied by significant differences in bacterial species abundance, suggesting that microbial genetics can reveal relationships overlooked by conventional microbiome analyses, although causality remains unproven.

5 Nov 2026

Inherited high cholesterol linked to slightly higher pre-eclampsia risk

Women with the inherited cholesterol condition familial hypercholesterolemia may be at a slightly higher risk of developing pre-eclampsia, a pregnancy condition that can cause serious complications, according to a new study in the European Journal of Preventive Cardiology.

4 Nov 2026

Faulty cellular recycling may link pulmonary arterial hypertension to brain damage

A commentary in The Journal of Clinical Investigation examines evidence linking pulmonary arterial hypertension (PAH) to cerebellar abnormalities, focusing on impaired lysosomal lipid metabolism, oxysterol accumulation, and microglial inflammation. Findings from human imaging, mouse models, and cultured cells suggest that NCOA7 may help protect against these changes, although the proposed mechanisms and therapeutic implications require further investigation.

4 Nov 2026

Multi-component nutritional supplement improves markers of vascular health

A multi-component nutritional supplement has been found to improve markers of vascular health, in a randomized controlled trial led by the University of Surrey.

4 Nov 2026

Eating peanuts every day may change your brains insulin response

The study finds that unsalted peanuts may enhance brain insulin responsiveness, providing new insights into dietary influences on cognitive health in aging.

4 Nov 2026

Key innate immune protein regulates cholesterol and influences cancer treatment resistance

Scientists at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered an unexpected role for a key innate immune protein, revealing how it helps regulate cholesterol levels inside cells and influences tumor growth and treatment response.

3 Nov 2026

Study identifies molecular links between menopause and brain aging

Researchers at UC Santa Barbara, UC San Francisco and international collaborators are uncovering the cascade of molecular events that happen when women undergo menopause, a time of life marked by endocrine changes and symptoms like hot flashes, brain fog and sleep disturbances.

2 Nov 2026

Long-term study supports cardiovascular safety of contemporary hormone replacement therapy

Contemporary hormone replacement therapy (HRT) was not associated with an increased risk for heart attack, stroke, blood clots or death among women ages 45 to 59, according to a large, long-term study of over 52,000 women in Israel.

2 Nov 2026

More screen time, less sleep: What researchers observed in children with obesity

A cross-sectional study of 70 children in Spain found that those with obesity reported more daily recreational screen time, shorter sleep duration, and more frequent chronic sleep disturbances than their normal-weight peers. Higher screen-time scores were significantly associated with greater odds of obesity, while the association with sleep disturbances did not reach statistical significance.

2 Nov 2026

Two healthy diets stood out in a study of more than 7,000 adults

In a cross-sectional analysis of 7,256 adults from the Maastricht Study, researchers found that greater adherence to the DASH and Dutch Healthy Diet patterns was associated with higher very-low-frequency (VLF) heart rate variability power, particularly among participants not taking beta-blockers. No significant associations were observed across time-domain HRV measures after full adjustment, and the findings do not establish that these diets improve cardiovascular function.

2 Nov 2026

Eating walnuts was linked to higher IgG levels, but what does that mean for health?

A two-year randomized trial involving 474 older adults found that daily consumption of 30–60 grams of walnuts was associated with 6% higher total serum IgG concentrations compared with a control diet, with an 11% difference observed among US participants. Walnut consumption did not significantly affect IgM, MDA-LDL or MDA-LDL-specific antibodies, and whether the modest IgG difference has meaningful cardiovascular benefits remains unknown.

1 Nov 2026

Study finds unexpected lower gut bacterial diversity in vegans

The gut is home to billions of microorganisms. It is a complex ecosystem that regulates many of the body's functions and helps keep us healthy – when it is in balance.

30 Oct 2026

Targeting ANO6 protein weakens pancreatic cancer and boosts immunity

Fox Chase Cancer Center researchers identified a potential therapeutic target for pancreatic cancer after showing that tumor growth can be slowed and immune suppression can be reduced in preclinical trials by blocking a particular protein, called anoctamin 6 (ANO6).

30 Oct 2026

New metabolic score may help predict healthy aging and disease risk

Studies conducted in various countries indicate that approximately 60% of people over the age of 65 currently live with two or more chronic conditions simultaneously.

29 Oct 2026

Worried nuts will cause weight gain? A large review puts that concern in perspective

A systematic review and meta-analysis of randomized trials found that eating nuts modestly reduced body fat and improved cholesterol levels without significantly changing body weight. The review did not establish that nuts rich in monounsaturated fats offered greater body-composition benefits than those rich in polyunsaturated fats.

29 Oct 2026

Cholesterol News and Research

Further Reading

UCLA study identifies lipid imbalance as pulmonary fibrosis trigger

Could a daily supplement keep blood vessels healthier as we age?

Cleaner bedroom air linked to improved blood sugar control

Early heart procedures do not improve long-term survival in stable heart disease

ZEUS trial challenges assumptions about targeting inflammation in heart disease

Hidden genetic differences in gut bacteria may hold clues to aging

Inherited high cholesterol linked to slightly higher pre-eclampsia risk

Faulty cellular recycling may link pulmonary arterial hypertension to brain damage

Multi-component nutritional supplement improves markers of vascular health

Eating peanuts every day may change your brains insulin response

Key innate immune protein regulates cholesterol and influences cancer treatment resistance

Study identifies molecular links between menopause and brain aging

Long-term study supports cardiovascular safety of contemporary hormone replacement therapy

More screen time, less sleep: What researchers observed in children with obesity

Two healthy diets stood out in a study of more than 7,000 adults

Eating walnuts was linked to higher IgG levels, but what does that mean for health?

Study finds unexpected lower gut bacterial diversity in vegans

Targeting ANO6 protein weakens pancreatic cancer and boosts immunity

New metabolic score may help predict healthy aging and disease risk

Worried nuts will cause weight gain? A large review puts that concern in perspective

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