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Nicotinamide riboside fails to slow progression of early Parkinson’s disease

A major clinical trial involving 410 people with early Parkinson's disease has found no clinical benefit from nicotinamide riboside (NR), a compound that increases cellular levels of nicotinamide adenine dinucleotide (NAD). The findings are published in JAMA.

8 Oct 2026

USC researchers receive $4 million to test psychedelic therapy and mindfulness for depression

A team of USC researchers has received an up to $4 million award from the Advanced Research Projects Agency for Health (ARPA-H) to conduct a clinical trial of psychedelic therapy and mindfulness training for depression.

6 Oct 2026

Experimental cancer drug works differently than researchers originally thought

A cancer drug currently being tested in patients may have entered clinical trials based on an incorrect understanding of how it works, according to a new study led by the University of Sydney in collaboration with Goethe University, Oxford University and the Institute of Cancer Research, London.

6 Oct 2026

Targeting the brain's Default Mode Network may help better manage chronic low back pain

Low back pain is the single leading cause of disability worldwide, according to the World Health Organization.

6 Oct 2026

Early nutrition should be central to measuring human development

Nutrition in the first 1,000 days of life should be a core measurement of development progress, argues former Ethiopian deputy prime minister Demeke Mekonnen following a week of debate on development issues at the United Nations General Assembly.

5 Oct 2026

Restoring cellular recycling helps the body clear harmful zombie cells

As we grow older, our bodies accumulate "zombie cells"-living cells that have stopped dividing or functioning normally-but linger in our tissues, contributing to chronic inflammation and age-related diseases.

5 Oct 2026

BioDuro appoints Greg Makara as Senior Vice President Lead Discovery Chemistry to strengthen early drug discovery capabilities

BioDuro, a global integrated contract research, development and manufacturing organization (CRDMO), today announced the appointment of Greg Makara, Ph.D., as Senior Vice President Lead Discovery Chemistry.

From BioDuro 5 Oct 2026

New strategy uncovers bioactive compounds from fragmented metagenomic data

Researchers have developed a practical strategy for recovering biosynthetic information from fragmented metagenomic data.

1 Oct 2026

NIH-funded trials will test pregnenolone for addiction and depression

Center for BrainHealth investigator Francesca Filbey, PhD, and UTSW investigator Sherwood Brown, MD, PhD, have secured two awards from the National Institutes of Health (NIH) to fund two major collaborative studies investigating whether the naturally occurring neurosteroid pregnenolone can help treat substance use disorders and co-occurring depression.

1 Oct 2026

Anti-fibrotic compound alters cell communication by redirecting cellular packages

An experimental anti-fibrotic compound can dramatically alter how cells release the microscopic packages they use to communicate, according to new research from the University of Surrey.

30 Sep 2026

MolBoolean™ measures free and bound proteins in the same experiment

Atlas Antibodies has launched MolBoolean™, a new in situ proximity assay. It detects free protein A, free protein B, and the A–B complex together in fixed cells and tissue.

From Atlas Antibodies AB 30 Sep 2026

Simulations reveal how changing enzyme shapes affect molecular recognition

Enzymes are often described as molecular machines that recognize and process specific molecules. However, they are not rigid structures. Their shapes can change, and these changes can affect how molecules enter, interact with, and remain within their active sites.

29 Sep 2026

New nanoparticles could protect soldiers from deadly nerve agents

Nanoparticles could someday provide a new way to help soldiers fight back against deadly nerve agents on the frontline.

29 Sep 2026

Review highlights emerging treatments for glioblastoma multiforme

A new research perspective was published in Volume 13 of Oncoscience on September 17, 2026, titled "Emerging pharmacological agents for glioblastoma multiforme: An update on active clinical trials (2025–2026)."

25 Sep 2026

Study identifies shared pathway driving cardiac fibrosis

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart.

24 Sep 2026

Smart contact lens measures stress levels by analyzing human tears

A research team led by Dr. Yangzhi Zhu, Principal Investigator and Assistant Professor at the Terasaki Institute for Biomedical Innovation (TIBI), has developed a soft, reusable smart contact lens as part of its broader Ocular Library for the Analysis of Tear Biomarkers (OCULAB), a tear bioelectronics platform for noninvasive, longitudinal biochemical monitoring through the ocular surface and tear film.

24 Sep 2026

C-Path awards $1.7 million to advance five drug development projects

Critical Path Institute (C-Path) today announced that its Translational Therapeutics Accelerator has awarded $1,699,500 through five Bridging Research and Innovation in Drug Development Grants (BRIDGe).

22 Sep 2026

Older adults with higher polyphenol intake were less likely to have mild cognitive impairment

In a cross-sectional study of 92 older Italian memory-clinic patients, higher habitual intake of total dietary (poly)phenols and several specific subclasses was associated with a lower likelihood of mild cognitive impairment (MCI). Total (poly)phenol intake was not associated with cognitive test performance or circulating inflammatory biomarkers, and the authors cautioned that the small observational study cannot establish causality.

20 Sep 2026

Shatavari may affect more than hormones, and the gut could help explain why

A review in Nutrients examined how bioactive compounds in Asparagus racemosus (Shatavari) may influence cognitive health through the microbiota-gut-brain axis, estrogen-related signaling, neuroinflammation, oxidative stress, and neurotransmitter regulation. Evidence from computational, cellular, animal, and limited human studies suggests several plausible biological pathways, but key questions remain about bioavailability, brain exposure, dosing, and clinical efficacy.

16 Sep 2026

Could a daily glass of orange juice support heart health? Study finds citrus compounds influence genes linked to blood vessel function

Naturally occurring compounds in orange juice regulated genes involved in the control of cardiovascular and blood vessel function, according to a new clinical trial.

16 Sep 2026