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AI redesign helps enzymes evolve beyond natural limits

Researchers showed that AI-redesigned botulinum neurotoxin proteases provided more stable starting points for directed evolution, allowing enzymes to access beneficial mutations that were poorly tolerated in wild-type backgrounds. In BoNT/E models, the approach improved activity, evolvability, and specificity, including an ataxin-2-targeting variant with markedly reduced cleavage of the native SNAP25 substrate.

24 Jul 2026

Researchers discover how cell membrane composition drives cancer proliferation

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment.

17 Apr 2026

Republicans fret over RFK Jr.’s anti-vaccine policies while MAHA moms stew

Health and Human Services Secretary Robert F. Kennedy Jr. is fielding pressure from the White House to relax his controversial approach to vaccine policies as the midterms near, but his most steadfast supporters are pressing for more aggressive action — like restricting covid-19 vaccines and pesticide use — to carry out the Make America Healthy Again agenda.

12 Mar 2026

Study reveals hidden internal structure within biomolecular condensates

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

25 Feb 2026

Sino Biological's launch of SwiftFluo® TR-FRET Kits pioneers a new era in high- throughput kinase inhibitor screening

Sino Biological, Inc. is proud to announce the launch of its innovative SwiftFluo TR-FRET Kinase Assay Kits, a ready-to-use, high-performance solution designed to accelerate kinase activity detection and high-throughput kinase inhibitor screening.

From Sino Biological Inc. 21 Jan 2026

Scientists uncover how cellular switches guide memory formation

When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new study from MPFI and Weill Cornell Medicine has revealed how two cellular switches, Rab4 and Rab10, direct supplies to where they are needed.

14 Oct 2025

Picoquant invests in Fluobrick Solutions to simplify access to single molecule research

PicoQuant GmbH announces its investment in FluoBrick Solutions GmbH, a newly founded Berlin-based start-up focused on giving life science researchers in academia and pharma diagnostics access to the power of single molecule techniques.

25 Sep 2025

Blood test detects Parkinson’s years before symptoms appear using RNA markers

A new study identifies a blood-based biomarker that detects pre-symptomatic Parkinson’s disease by measuring the ratio of specific nuclear and mitochondrial transfer RNA fragments. The test outperforms standard clinical tools and may also reflect disease mechanisms related to impaired protein synthesis.

14 Apr 2025

Breakthrough discovery opens doors for targeting adhesion GPCRs with drugs

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with each other.

18 Dec 2024

Voters fret high medical bills are being ignored by presidential rivals

Tom Zawierucha, 58, a building services worker in New Jersey, wishes candidates would talk more about protecting older Americans from big medical bills.

24 Oct 2024

How Minnesota figures into the presidential politics of insulin prices

In June 2019, Lija Greenseid handed Minnesota Gov. Tim Walz an empty vial of insulin that her 13-year-old daughter had painted gold.

1 Oct 2024

Revolutionizing hepatocyte count for researchers

In this interview, NewsMedical speaks to DeNovix's Dan Schieffer about the new app developed for CellDrop, and how it aims to revolutionize hepatocyte count for the drug discovery industry, and more.

From DeNovix Inc. 29 Jul 2024

Finland is offering farmworkers bird flu shots. Some experts say the US should, too.

As bird flu spreads among dairy cattle in the U.S., veterinarians and researchers have taken note of Finland's move to vaccinate farmworkers at risk of infection. They wonder why their government doesn't do the same.

11 Jul 2024

Sphere Fluidics launches Cyto-CellectPLUS to accelerate cell line development workflows

Next-generation assay provides a rapid and cost-effective solution to quantify IgG production in single cells.

From Fluidic Sciences and Sphere Bio 4 Jun 2024

Decoding the function of SRSF1 protein in RNA splicing and translation regulation

RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence.

30 May 2024

Innovative Subak tool offers affordable solution for detecting nuclease digestion

A new tool could reduce costs for diagnosing infectious diseases.

27 Feb 2024

A record number of Californians are visiting emergency rooms for dog bites

Those pandemic puppies are growing up to be a public health concern.

26 Jan 2024

New discovery sheds light on how BRCA1 mutations cause cancer in women

Three decades after discoveries linking mutations in the BRCA1 gene to breast and ovarian cancer susceptibility, research led by Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has pinpointed the molecular mechanism by which a large portion of these mutations cause cancers in women.

9 Oct 2023

As more patients email doctors, health systems start charging fees

Meg Bakewell, who has cancer and cancer-related heart disease, sometimes emails her primary care physician, oncologist, and cardiologist asking them for medical advice when she experiences urgent symptoms such as pain or shortness of breath.

14 Sep 2023

Low-molecular weight human interleukin-1β antagonist discovered

Researchers described the detection of a human interleukin-1β antagonist with low molecular weight that disrupts interactions with the interleukin-1 receptor type I receptor.

11 Sep 2023