Gastrointestinal Cancer News and Research

RSS

Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract, including the esophagus, stomach, liver, biliary system, pancreas, bowels, and anus.

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or are not candidates for multiagent systemic therapy.

From Dana-Farber Cancer Institute, Inc. 29 Aug 2026

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

27 Aug 2026

Special journal issue highlights precision prevention in cancer epidemiology

Cancer epidemiology is not merely about counting cases; it is a dynamic field that informs screening policies, resource allocation, and clinical trial design.

19 Aug 2026

Dyadic coping mediates cancer recurrence fear and survivor depression

Advances in diagnosis and treatment have extended survival for many people with gastrointestinal cancer, increasing attention to their long-term psychological health.

13 Aug 2026

Expanded DepMap reveals new cancer vulnerabilities through 3D tumor models

For nearly a decade, the Cancer Dependency Map, or DepMap, at the Broad Institute has helped scientists uncover new cancer dependencies - the genetic changes some cancers need to thrive that can potentially be targeted by new cancer drugs.

5 Aug 2026

Daraxonrasib significantly extends survival in metastatic pancreatic cancer

At the ASCO annual meeting, Dana-Farber's Brian Wolpin, MD, MPH, will present positive results from the RASolute 302 trial showing a substantial prolongation of survival for patients with previously treated metastatic pancreatic cancer, regardless of RAS mutation status, taking daraxonrasib, an investigational oral RAS(ON) multi-selective inhibitor, compared with chemotherapy.

31 May 2026

Roswell Park scientists present five key cancer studies at clinical meeting

The research findings of experts from Roswell Park Comprehensive Cancer Center will be featured during the American Society of Clinical Oncology (ASCO) annual meeting May 29 to June 2 at McCormick Place in Chicago.

25 May 2026

Most Americans would consider swapping classic Super Bowl party fare for plant-based options, poll finds

It is estimated that Americans will consume 1.48 billion chicken wings during the Super Bowl, but a new Physicians Committee for Responsible Medicine/Morning Consult poll finds that most Americans, 56%, would consider trying a plant-based alternative such as Baked Buffalo Cauliflower Bites while watching the New England Patriots and Seattle Seahawks on Feb. 8.

31 Jan 2026

Researchers identify nervous system components driving gastrointestinal cancer growth

Australian researchers have identified two nervous system components that drive tumor growth in gastrointestinal cancers, creating promising new avenues for treatment with existing approved therapies.

24 Oct 2025

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

29 Aug 2025

Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients

For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease.

7 Aug 2025

Most Americans oppose fast food sales in hospitals

Fast food like cheeseburgers, fried chicken, and pizza shouldn't be sold in hospitals, say most Americans in a new Physicians Committee for Responsible Medicine/Morning Consult poll.

5 Aug 2025

New computer program mimics cell behavior for faster medical discoveries

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025

Early-onset gastrointestinal cancer rates rising across the globe

A new paper in BJS, published by Oxford University Press, indicates that early-onset gastrointestinal cancer rates are rising dramatically across the globe.

8 Jul 2025

Gut bacteria help ease chemotherapy side effects and aid recovery

Intestinal microbes that survive chemo can rid the gut of excess chemo drugs and produce a vitamin that helps to stem nausea.

21 May 2025

Gastrointestinal cancer patterns vary across diverse Asian and Pacific Islander populations

The incidence of gastrointestinal cancers varies across Asian American, Native Hawaiian and other Pacific Islander communities, according to a study published March 15 in the journal Gastro Hep Advances.

7 May 2025

New study questions poultry's health halo amid rising cancer risks

A new analysis from Italian cohort studies found that consuming over 300 g of poultry per week is linked to significantly increased risk of death from gastrointestinal cancers, especially in men. Moderate meat intake, particularly red meat in controlled quantities, was paradoxically associated with reduced all-cause mortality.

23 Apr 2025