Hyperpigmentation News and Research

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Hyperpigmentation is one of the most common pigmentation problems in darker-skinned individuals is hyperpigmentation (or the darkening of the skin). Usually the result of some type of inflammation or injury to the skin, such as a cut, burn or scrape, hyperpigmentation produces darkened areas of the skin that can last months or years. Even healed acne lesions can leave permanent dark spots in darker-skinned people that, in some cases, can be more distressing than the original acne.

Cosmetic microneedles deliver actives where creams struggle

This review shows how microneedle-based cosmetic systems bypass the stratum corneum to deliver poorly penetrating actives, including peptides, retinoids, vitamins, niacinamide, hyaluronic acid, and hair-growth compounds, into viable skin layers.

8 Jul 2026

Scientists uncover immune mechanisms driving rare gastrointestinal disorder

A collaborative team led by Dr. Jingnan Li and Dr. Ji Li at Peking Union Medical College Hospital, together with Associate Professor Xiaohuan Guo at Tsinghua University and Academician Ye-Guang Chen at Tsinghua University School of Life Sciences, published a study in Volume 2, article number 28 of the journal Immunity & Inflammation on June 17, 2026.

26 Jun 2026

Unexplained skin darkening leads to life-saving Addison's disease diagnosis

A 24-year-old woman presented with two years of unexplained darkening of her hands, feet, gums, and tongue.

26 Jun 2026

Skin of color seminar improves medical students’ diagnosis skills

A seminar improved medical students' ability to identify skin conditions in darker skin tones, addressing diagnostic gaps in diverse patient populations.

23 Feb 2026

Fad diets and supplements fuel new wave of hidden skin problems, study finds

A new review explains how fad diets and unregulated supplements promoted online can cause serious skin, hair, and nail problems, often before other symptoms appear. Clinicians are urged to recognize these risks and address health misinformation in the digital age.

22 Jul 2025

$Hypofractionation proven safer and more convenient for breast cancer treatment$

Hypofractionation proven safer and more convenient for breast cancer treatment

Giving higher doses per fraction of radiation therapy over a shorter time after breast cancer surgery significantly reduces the risk of side effects and improves quality of life compared with a conventional schedule, finds a study published by The BMJ today.

13 Sep 2024

Fish gut bacteria may provide new ingredients for skincare

There are some pretty strange ingredients in cosmetics and skin care products. One example is snail mucin - also known as snail slime - which is used for its moisturizing and antioxidant properties.

5 Sep 2024

Natural compound from skin bacteria shows promise as tyrosinase inhibitor for skincare

Melanin protects the skin - the body's largest organ and a vital component of the immune system - from the damaging effects of ultraviolet (UV) radiation.

5 Aug 2024

Diet and nutrition's influence on acne vulgaris

Study highlights the significant role of certain dietary components, such as dairy, chocolate, and fats, in the development of acne vulgaris and underscores the need for further research to inform effective dietary recommendations.

19 May 2024

MONET: New AI tool enhances medical imaging with deep learning and text analysis

MONET aids in critical tasks in medical artificial intelligence (AI) development and implementation.

19 Apr 2024

Mediterranean diet supercharges skin treatment, clears up atopic dermatitis in teen

Study reports on a 14-year-old boy with atopic dermatitis who experienced complete symptom resolution after combining monoclonal antibody treatment with a Mediterranean diet. Highlighting the role of diet in managing inflammatory skin conditions, the case study suggests the therapeutic potential of integrating dietary changes with medical treatment for improved outcomes.

10 Sep 2023

Unique plant extract mixture has potent anti-acne effects

Researchers evaluate the efficacy of FRO, a formula composed of fermented Rhus verniciflua Stokes and Orostachys japonicus, against acne pathogenesis via antimicrobial assessment and an in vitro analysis. FRO was found to contain phenolics such as gallic acid, fisetin, quercetin, and kaempferol and was determined to alleviate acne by inhibiting the growth of Cutibacterium acnes, inflammation, and excess sebum.

9 Jul 2023

Researchers discover the Nrf3-mediated mechanism of melanogenesis

The skin is presumably the largest and one of the most versatile body organs. By providing a physical barrier, it protects our body from environmental assaults.

11 Jan 2023

FLASH radiotherapy may hold promise as a potential treatment for tough-to-kill tumors

FLASH radiation treatment – which delivers therapeutic doses of radiation in a fraction of a second – may hold promise as a potential treatment for tough-to-kill tumors, a first-in-human study in a small number of people with bone cancer suggests.

24 Oct 2022

Burt's Bees research shows the benefits of nature-based regimens to protect and restore skin health

Burt's Bees, the #1 dermatologist recommended natural skin care brand and a pioneer in this area, announced its latest research findings on the benefits of nature-based regimens to protect and restore skin health across various skin conditions, types, and tones.

30 Sep 2022

Lab-grown ‘pigmented’ skin-equivalent commercially available for the first time

Labskin and University of Bradford team up to bring new science in skin health to greater diversity for skin types.

27 Sep 2022

Monkeypox virus infection in an immunocompromised patient

Researchers assessed the manifestations of the monkeypox infection in an immunocompromised patient.

19 Sep 2022

A dermatological approach to diagnosing monkeypox

Scientists present their dermatological approach to a suspected monkeypox case.

16 Aug 2022

Kratom: A dangerous or beneficial plant?

A new study summarizes the traditional and modern uses of kratom, as well as its pharmacology, benefits, and adverse health impacts.

23 Jun 2022

New book explains the functional aspects of melanogenesis and related disorders

The Vertebrate Pigmentary System: From pigment cells to disorders provides readers with fundamental knowledge of the structural and functional aspects of vertebrate pigment cells - melanophores and melanocytes - from their origin to different stages of development to related diseases.

22 Mar 2021